AdlungLab Systems Immunology

🦋 Hi friends, you'll find me elsewhere, where the sky is bluer: bsky.app/profile/adlung…

One thing we know, another thing we can't avoid: Infection and aging partially converge in spatial transcriptomics data of mice. Great work by our good friend and esteemed colleauge @fabiankern13 👏 biorxiv.org/content/10.110…

Great piece by @_bunnech et al. on optimal transport for single cell and spatial omics. Really curious about practical implications in the future: nature.com/articles/s4358…

We are looking for exceptional MSc and PhD students! 👩‍🔬🧪🔬🧑‍🔬🧫💩 If you're interested in exploring the interface between gastrointestinal tract immunity and the microbiota in various diseases and combining basic science with NGS in the best environment possible - send me a DM

I'm honoured to be awarded the Dr. Liselotte-Brauns Research Prize for Internal Medicine this year. Great feedback for my project ideas, can't wait to put them to the test 🤓 stiftung-drbrauns.de stiftung-drbrauns.de/die-preistraeg…

I like this concept of intestinal tuft cells: weep, sweep … secrete - @NatRevImmunol nature.com/articles/s4157…

Game changer alert!!! 🧫 🦠 Discovery of antimicrobial peptides in the global microbiome with machine learning: Cell cell.com/cell/fulltext/…

Great work in @NatureCancer on how to utilise single-cell data to predict cancer patients' response to different drugs. I see wide applicability even beyond tumours! nature.com/articles/s4301…

@ost_mario Correct! How come I mixed that up?! Sorry... 🥴

You knock out enteroendocrine cells from the small intestine and your metabolism goes berserk! nature.com/articles/s4225…

Hamburg news: The ⁦@krebs_lab⁩ and collaborators used iCROP-seq to identify TH17 cell plasticity as a potential new therapeutic target in autoimmunity. ⁦@HCKH_Hamburg⁩ ⁦@UKEHamburg⁩ ⁦@unihh⁩ science.org/doi/10.1126/sc…

Wonderful conceptual work. Must-read if you seek inspiration on modelling!

Slowly, I gain a better and better understanding why bile acids should be closer to my heart (in a metaphorical way only!) @natmetabolism nature.com/articles/s4225…

Beautiful paper from the @AdlungLab :) the first one out of many! Congrats!!!!

If you want to learn more about ODE-based modeling of longitudinal single-cell data to gain a better understanding of immune dynamics check out @AdlungLab s most recent paper doi.org/10.1038/s41540…

🏁 Read the full paper here: rdcu.be/dLMdS #oa #openaccess And all the framework: github.com/AdlungLab/scIB… 9/9

🙏🏻 Work by (who's here): @KilianChristoph & Hanna Ulrich, @ZouboulisV, ..., @marenbuettner, @bitonm, @ejvillablanca. Thanks, @BaiomeH for support! Thanks, @dfg_public, @ktstiftung and @hh_bwfgb for funding. And thanks to @mkjolly15 for excellent editorial handling! 8/

What do we need to understand inflammatory bowel disease (🔥) besides single-cell data and machine learning? ... ⏰ 🥁 Here comes the first paper from the group, out now @Nature_NPJ: nature.com/articles/s4154… 🧵