5. Many thanks to @STOPlabPI , @DPulimamidi, @real_lab_duck, Maxime Lalonde, @kopczynska_m , Shazia Irshad, Hiroshi Kimura, @michal_gdula , and Stephan Hamperl for a great collaboration on this project. 6/6
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Agata Stepien
65 posts
Agata Stepien
@AgataKStepien
Transcription and RNA processing; postdoc in @STOPlabPI group @UAM_IBMiB
Katılım Mart 2020
205 Takip Edilen158 Takipçiler
4. Shortening of the distance between pre-mRNA cleavage and RNAPII terminal pausing is associated with higher gene expression❗️
Shortened spacing = higher expression BUT also higher addiction to PCF11 and CPSF73. 5/6
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Did you know that changes in pre-mRNA 3' cleavage and RNAPII termination can go in different directions? Even more, the spacing between these two events is linked to the gene expression level❗️Check out our latest pre-print to learn more tiny.cc/330w001 1/6
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Agata Stepien retweetledi
HIRING! STOP lab is looking for a Research Assistant (Technician) with experience in protein expression and purification @czt_uam @UAM_IBMiB @UAM_Poznan. Job & project description and how to apply here: euraxess.ec.europa.eu/jobs/367610
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Agata Stepien retweetledi
🚀 We’re hiring a #Postdoc!
Join our group in Poznan, Poland to study meiotic crossover recombination in plants🌱 Highly motivated & enthusiastic candidates are welcome!
📅 Deadline: Nov 1, 2025
🔗 ibmib.web.amu.edu.pl/wp-content/upl…
#PlantScience #Meiosis #PostdocJobs
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A beautiful story about the role of SETD2 in RNAPII transcription 💗
Kinga Kamieniarz-Gdula #StayWithUkraine #NCNtoTlen@STOPlabPI
🚨New preprint from our labs (STOP lab & Nojima lab @pol2rna)! @kopczynska_m and Chihiro Nakayama have been digging into how chromatin remodeller SETD2 controls the start and end of transcription 👇 (1/5) biorxiv.org/cgi/content/sh…
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Agata Stepien retweetledi
1/6 Buckle up folks: our new paper in @ScentificReports is out! Interested in insect cells culturing? Together with Ewa Stein @ESte_late, Martyna Plens-Gałąska @real_lab_duck & Kinga Kamieniarz-Gdula @STOPlabPI @UAM_IBMiB & @czt_uam we provide a story about #Sf cells-BEVS system.
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Agata Stepien retweetledi
Happy to share with you our new @Nature story about the crucial role of TENT5A-mediated re-adenylation of mRNA COVID-19 vaccines in boosting their efficacy. We also show how important macrophages are in producing the antigen following vaccination. nature.com/articles/s4158… @
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Agata Stepien retweetledi
Great news & strategic decision @donaldtusk @Domanski_Andrz: 500 mln top-up for🇵🇱research @NCN_PL in 2025!!!
Strengthening high Q basic research is the best way to drive true INNOVATION and INVEST in the FUTURE of 🇵🇱&🇪🇺
A frontline country can do it - what's your gov's excuse?
Andrzej Domański@Domanski_Andrz
Każda złotówka zainwestowana w badania i innowacje generuje od 4 do 7 zł zwrotu w gospodarce. Dziś Premier @donaldtusk przekazał kolejne 0,5 mld zł na Narodowe Centrum Nauki @NCN_PL, które wspiera działalność naukową w zakresie kluczowych badań podstawowych. Potrzebujemy innowacyjnej gospodarki i budowania nowych silników wzrostu gospodarczego 🇵🇱
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Agata Stepien retweetledi
Co wyniknie z dzisiejszego spotkania Komisji Finansów Publicznych? #TakDlaNauki i #TakDlaRozwoju czy trzymanie naszego kraju na poziomie taniej montowni? @CichonJanusz @kr_szumilas @Domanski_Andrz @wieczorekdarek @dorota_olko @ZandbergRAZEM @donaldtusk @ForumAkad @naukawpolsce
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Agata Stepien retweetledi
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Agata Stepien retweetledi
Dorota Raczyńska team @UamPlab from @UAM_IBMiB discovered that U7 #snRNA supresses HERV1/LTR12s repeats & lincRNAs in human cells congratulations to the team! Check it out @NAR_Open! #479538076" target="_blank" rel="nofollow noopener">academic.oup.com/nar/advance-ar…
UAM PLAB - Laboratory of RNA Processing@UamPlab
Delighted to announce that our paper, "Novel function of U7 snRNA in the repression of HERV1/LTR12s and lincRNAs in human cells", has been published in Nucleic Acids Research! 🎉🎉🎉 @NAR_Open @UAM_IBMiB Check it out 👍academic.oup.com/nar/advance-ar…
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A beautiful story about U7 snRNA and LTR12s😍 I'm very happy that I could be a part of this work!
UAM PLAB - Laboratory of RNA Processing@UamPlab
Delighted to announce that our paper, "Novel function of U7 snRNA in the repression of HERV1/LTR12s and lincRNAs in human cells", has been published in Nucleic Acids Research! 🎉🎉🎉 @NAR_Open @UAM_IBMiB Check it out 👍academic.oup.com/nar/advance-ar…
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I am extremely happy to share that I was awarded the Sonatina grant to explore the meiotic recombination in pericentromeres 🥳 🥳 The project is soooo exciting that it deserved to be the FIRST on the ranking list!
Narodowe Centrum Nauki@NCN_PL
35 młodych naukowczyń i naukowców już niedługo rozpocznie realizację projektów badawczych dzięki finansowaniu z #NCN. Granty przeznaczą na badania, zatrudnienie w polskich jednostkach i staże zagraniczne. ncn.gov.pl/aktualnosci/20… #SONATINA #konkursyNCN
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Agata Stepien retweetledi
Looking for an exciting #PhD project in #molecularBiology? How about this question: what determines a gene's end? Most human genes have alternative ends, the choice of which is important for health and disease. Yet we still don't understand how this choice is made!
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Agata Stepien retweetledi
Excited to share Vclust! It's a fast and accurate tool for calculating intergenomic similarities (like ANI) and clustering virus/#phage genomes/contigs according to ICTV and MIUViG standards.
💻 Tool: github.com/refresh-bio/vc…
📄 Preprint: biorxiv.org/content/10.110…
Thread! 1/6 ↓
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Agata Stepien retweetledi
Check our latest paper to find out more about RAM role in cap formation and T-cell growth and activation!
Discovery Immunology Journal@discovimmunol
Investigating the role of RAM in #Tcell activation🅰 Katarzyna Knop et al. @CRUK_SI carried out gene deletion experiments highlighting RAM's pivotal role in RNA cap formation, gene expression & #CD4 T cell growth & proliferation 👉bit.ly/48EREEu
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