Alberto Macho

Slowly migrating to Bluesky @albertopmacho.bsky.social

Together with our previous report earlier this year (Yu et al, PLoS Pathogens, 2025), this work suggests that hijacking plant kinases is an important strategy for bacterial effectors to promote their own phosphorylation and stability in plant cells doi.org/10.1371/journa…

These phosphorylation sites seem to be important for RipBM contribution to virulence in tomato, reflecting an effector strategy to promote its own stability and contribute to bacterial virulence

Our latest paper is now online at New Phytologist!   Phosphorylation-dependent association of a bacterial effector with plant 14-3-3 proteins enhances effector stability and bacterial virulence   doi.org/10.1111/nph.70… @NewPhytol

Our new paper is out in New Phytologist! We describe how the Ralstonia solanacearum effector RipAV suppresses plant immunity by directly interfering with key defense regulators. 🧵👇 nph.onlinelibrary.wiley.com/doi/10.1111/np…

🎉 Thrilled to announce that CoBEPP — Using conserved bacterial effectors to probe plant-pathogen interactions — has been funded by @AgEInves & @cienciaGob! Grateful for the support to launch my first project at @IHSM_CSIC_UMA, exploring how pathogens affect plant biology! 🌱🔬

Hopefully, the information that heterologous PRR expression can confer novel PAMP recognition could provide new information for the design of synthetic immune receptors with expanded recognition of polymorphic pathogen elicitors

Long story short, it seems that AtFLS2, when expressed in N. benthamiana, associates with NbSERKs and mediate a “partial” complex activation that leads to some downstream responses (MAPK, gene expression), but not others (ROS). Eventually, this enhances disease resistance

Our latest article is now online! @PlantBiotechJ Expression of Arabidopsis FLS2 in N. benthamiana confers responsiveness to Ralstonia flg22 and activation of anti-bacterial immunity doi.org/10.1111/pbi.70… By Meng Li, Yujiao Chen, and Yali Wei (@albertopmacho.bsky.social)

📜 El #CSIC firma dos memorándums de entendimiento con la @CAS__Science  🏛️ Ambas instituciones promoverán la cooperación científica centrada en proyectos sobre agricultura sostenible, alimentación y cambio climático 👉 tiny.cc/s5km001

🇨🇳🇪🇸La ciencia es un lenguaje universal Hoy el @CSIC ha firmado un acuerdo de colaboración con el principal organismo científico chino, CAS, y la activación inmediata de un programa de intercambio de investigador@s entre las 2 instituciones Gracias al Presidente Hou Jianguo!

📋 New paper from our researchers Carmen Beuzón, Javier Ruiz-Albert, Nieves López-Pagán and José Rufián! Published at @NatureMicrobiol More information here! ⬇️ nature.com/articles/s4156… @InfoUMA @CSIC

Proud to share our must-read preprint, where we unveil a novel MAMP-immune receptor pair and pioneer the design of synthetic receptors to expand plant immune surveillance. Huge congratulations to @BrunoNgou, I couldn’t be prouder of this breakthrough. biorxiv.org/content/10.110…

We are glad to write a spotlight on this interesting work "science.org/doi/10.1126/sc…. Non-adapted bacterial infection suppresses plant reproduction". Bacterial T6Es can do more than we thought.

Control biológico | Los grandes aliados de la #agricultura 🐞🪲

Humans have been modifying crops for thousands of years. We shouldn’t fear genetic engineering. It is simply an extension of what humans have been doing for thousands of years, just with greater precision and accuracy.