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Eva Alderman
1.1K posts
Eva Alderman
@AldermanEva
sparklepony @superbioai
United States Katılım Ekim 2016
821 Takip Edilen144 Takipçiler
Eva Alderman retweetledi
At last I understand why it costs 100x more to discover a drug today than in 1950. Our computers have slowed down.
Dr Singularity@Dr_Singularity
We will now be able to discover new drugs 1000s of times faster. Thanks to AI, all diseases will be curable during the 2030s. MADD - Multi Agent Drug Discovery Orchestra, a multi agent AI system designed to massively accelerate the early stages of drug discovery, especially hit identification. It uses four cooperating agents to break down a user’s query, generate molecules, evaluate them, and return the best drug candidates. Across benchmarks and real case studies (e.g., Alzheimer’s, thromboxane inhibitors), MADD outperforms existing AI systems in accuracy, molecule quality, and the number of viable hits. It shows that agentic LLMs can run identification pipelines automatically, dramatically accelerating drug discovery.
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@owl_posting Anecdotally all the bodybuilders I know have been on tirzepatide (or reta!) for at least 6 months
Honestly give it <12 months until everyone is using GLPs to lose weight
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tirzepatide has economically outclassed one of the most profitable drugs of all time by 25%
bonkers
but an interesting datapoint is that keytruda, when it was approved in 2014, didnt actually seem to move mercks stock price much, probably because it was initially just approved for melanoma, and people didn't realize it was eventually going to be approved for basically every type of cancer
today, tirz is approved for the following indications: T2 diabetes, obesity, and overweight + one major health complication
and tirz is currently in clinical trials (or strong evidence to imply there eventually will be one) to expand into the following indications: osteoarthritis, chronic kidney disease, idiopathic intracranial hypertension, PCOS, type 1 diabetes, alcohol use disorder, MASLD/MASH, major adverse cardiovascular events, and pediatric obesity
i love big pharma so so so so much
Adam Feuerstein ✡️@adamfeuerstein
$LLY Q3 tirzepatide (Mounjaro/Zepbound) sales: $10.1 billion. $MRK Q3 Keytruda sales $8.1 billion. The passing of the torch...
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Grateful to the @arcinstitute for the Ignite Award, especially in these challenging times. Congrats to all the other awardees including the two new core members & the 7 innovation awardees.
Look forward to continue collaborating with several teams at Arc.
Arc Institute@arcinstitute
Arc's community continues to grow this fall with our 9th Core Investigator @jvpluv and 3rd Science Fellow @maya_m_arce joining us in Palo Alto, along with 7 Innovation Investigators and 15 Ignite Awardees at our partner universities. Learn more: arcinstitute.org/news/faculty-a…
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Life update: I’ve decided to take some time off from Stanford.
I've seen a lot of these "dropping out of college" posts, but I never thought I’d write one myself. To be completely honest, I never seriously considered taking a leave or dropping out. Interning at @modal this past summer changed my plans.
People often talk about @modal's talent density, but working within it gave me a whole new perspective on what “exceptional” looks like in engineering, product, design, GTM, and most importantly, in company culture. I wanted to keep learning in this environment, especially now. Over just a few months interning at @modal this summer, I saw Lovable create 1M+ sandboxes on @modal, the launch of Modal SDK 1.0, GPU Performance Glossary, GPU Memory Snapshots, multi-node training clusters, @modal Notebooks, and so much more.
I felt this was the moment to join and build the infrastructure for the entire AI/ML lifecycle, the way it should be. So I'm excited to share that I'm starting full-time at @modal today, alongside the announcement of @modal's Series B!
It was a tough choice to step away from Stanford, even for a little while, but I’m excited to continue learning and growing with this team. If you're a student who want to work with incredible engineers, be part of a truly welcoming culture, and join in on karaoke or goat-petting events, or if you’re unsure about taking time off, I’d be happy to share my experience!
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@dr_alphalyrae So true, although I've seen it go the other way as well - just ask a new SWE at a biotech to get caught up on on immunology in 6 months
Some will do great, some won't. The bio learning curve is messy...
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Going from biotech to tech was an unexpectedly humbling experience, almost an egodeath. In biotech, doing bioinformatics during a PhD or postdoc is considered highly technical, you’re the “computer person” in a world of wet-lab scientists. But in tech, that experience doesn’t carry the same weight. If you haven’t trained a billion-parameter model or built a platform from scratch, you’re not seen as “technical” enough. The shift kinda forces you to rethink what being “technical” really means. Or perhaps we're in this bay area bubble of accusing each other of not being 'technical enough' till death takes us.
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Oh boy. Very exciting. I wonder what interventions are almost certainly causing autism? What could it be? What could it be? I wonder. I wonder.
The Real Truther@thereal_truther
Trump: “The autism is such a tremendous horror show…how are you doing on that?” RFK Jr: "We're finding certain interventions now that are almost certainly causing autism. We’re going to be able to address those in September."
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Eva Alderman retweetledi
Looking for an energy expert to interview on my podcast. I want to get in the weeds on what will happen the wild AI worlds.
As AI actually becomes capable of substituting for human labor, your country's GDP will be denominated by your AI population size, which is downstream of energy.
What does this mean for different countries? Given how fast the US falling behind China in electricity generation, what would it take for us to make up the ground?
What are the most plausible sources (natural gas, nuclear, solar), what are their supply curves, the main physical or regulatory bottlenecks that would slow down a ramp up, etc.
Who's the right guest to chat this through?
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Eva Alderman retweetledi
yeahhh .. “let’s make it harder for immigrants to study and work in the states”
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Eva Alderman retweetledi
Harvard researcher Dr Sarah Fortune was only two years away from creating a vaccine that could have saved the 1.25 million people killed each year by tuberculosis. But last month, she received a letter telling her that the $60 million grant funding her research was being halted by President Trump.
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In America, we have the Cult, and we have everyone else.
This week has been very instructive about which public figures are in the Cult and which are not.
Noah Smith 🐇🇺🇸🇺🇦🇹🇼@Noahpinion
Trump's approval rating continues to inch downward. It takes a while for Americans to collectively realize they made a huge mistake, but they will realize.
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Eva Alderman retweetledi
UC Berkeley open-sourced a 14B model that rivals OpenAI o3-mini and o1 on coding!
They applied RL to Deepseek-R1-Distilled-Qwen-14B on 24K coding problems.
It only costs 32 H100 for 2.5 weeks (~$26,880)!
It's truly open-source. They released everything: the model, training code, dataset, and a detailed blog (links in the thread).
Finally, a powerful coding model we can run locally. I hope Sam can open-source something better than this.
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Eva Alderman retweetledi
Eva Alderman retweetledi
When we did steel tariffs, it added 1,000 steel producer jobs and subtracted 75,000 steel user jobs
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Eva Alderman retweetledi
well, assuming zero negative impact on the global economy, zero retaliation, and 100% capitulation so other countries pay the full incidence of tariffs, ~25% of U.S. imports, annual revenue would be about one-tenth the amount the U.S. stock market has lost in the past 8 weeks
Rick Arnonal@RickArnonal
@EpsilonTheory @SlaterHeil Anyone estimating how much money will be collected from tariffs over next month/three months/year? Surprised no one I'm aware of is even making a guess.
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Eva Alderman retweetledi
Searching for uncorrelated stores of value... anyone heard of this S&P500 proxy, Bitcoin?
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