Allen Jiang

Today in @CellCellPress we report the use of prime editing to correct several mutations that cause alternating hemiplegia of childhood (AHC), a rare and devastating neurodevelopmental disorder, in patient-derived cells and in two mouse models. drive.google.com/file/d/1ibC50t… 1/10

Breaking News: A baby with a rare disorder made medical history by receiving the first custom gene-editing treatment. The technique used has the potential to help people with thousands of other uncommon genetic diseases. nyti.ms/4j3xGs8

My future lab will apply drug delivery, genome editing, and chemical engineering principles towards developing non-viral, nucleic acid delivery systems that enable safe and effective genome editing therapies

I'm grateful to the many amazing mentors, colleagues, and collaborators that have supported me on this journey, including my PhD advisors Bob Langer and Dan Anderson and my postdoc advisor @davidrliu

I'm excited to share that I will be joining @UclaCBE as an Assistant Professor starting July 2027!

Happy to share our latest manuscript published in Nature Protocols @NatureProtocols @NaturePortfolio named: “mRNA lipid nanoparticle formulation, characterization and evaluation”! @ma_yutian @rachel_vkm @UNC @UNCPharmacy @DPMP_UNC Manuscript link here: rdcu.be/ec3lX

@SwingleKelsey @Nature @pennbioeng @MJMitchell_Lab Congrats Kelsey!!

Thrilled to share our recent work out today in @Nature on an mRNA therapeutic to treat pre-eclampsia! This work has been a true passion project from my time @pennbioeng in @MJMitchell_Lab, and I’m excited to continue important research in women’s health! nature.com/articles/s4158…

@Lulu_Xuee @J_A_C_S Thank you Lulu!

@AllenYJiang @J_A_C_S Congrats Allen!

Excited to share the last piece of my PhD thesis published today in @J_A_C_S where we engineer zwitterionic polymer modified LNPs to replace PEG and stabilize LNPs during nebulization, enabling efficient inhaled mRNA delivery: pubs.acs.org/doi/10.1021/ja…

@TheFentonLab @J_A_C_S Thanks Owen!

@AllenYJiang @J_A_C_S Congrats!!

Huge thanks to co-author @Dr_S_Lathwal, former undergrad Sabrina Meng, and all the other folks in the Langer and Anderson labs for this awesome collaboration! @MITChemE @kochinstitute

@js_zeng Huge congrats, Joy!

Thrilled to announce that I will start as an Assistant Professor of Engineering (Chemical and Environmental) at Brown in July 2025! My lab will develop new electrocatalysts to address grand challenges in energy storage, chemical synthesis, and waste remediation.

Scientists have developed a prime editing approach that efficiently corrects the most common cystic fibrosis mutation in human lung cells, which could pave the way to a one-time treatment as effective as existing daily therapies. broad.io/CF-PrimeEditin…

Excited to share our latest research published in @NatureMaterials nature.com/articles/s4156… It showcases an innovative approach combining machine learning with advanced combinatorial chemistry to enhance the discovery of ionizable lipids that are crucial for mRNA delivery.

Honored to have received the Controlled Release Society's PhD thesis award! This award wouldn't have been possible without the support of my PhD advisors Bob Langer and Dan Anderson @MITChemE @kochinstitute controlledreleasesociety.org/2024-award-rec…

2024 SUGAR BOWL CHAMPIONS 🏆 SEE YOU IN HOUSTON ☔️ #USvsUS #PurpleReign

2023 PAC-12 CHAMPIONS 🏆☔️ #USvsUS

Huge thanks to all the collaborators in the lab who helped make this work possible! @sayoeweje @corina_macisaac @YizongHu @MananRajith and talented undergrads Sabrina and Favour

Thrilled to also share a major piece of my PhD thesis from the Langer and Anderson lab out today in @NatureNano. Working with @JacobWitten1 and @w_idris, we developed nebulizer stabilized, inhalable LNPs for pulmonary mRNA delivery! nature.com/articles/s4156…

After 5.5 incredible years @MITChemE and @kochinstitute, I'm excited to announce that I recently defended my #PhD! A huge thank you to my advisors, Profs. Bob Langer and Dan Anderson, and for all those in and out of the lab who supported me throughout this journey!