Sabitlenmiş Tweet
… aaand the Andréasson lab is finally online!
Make sure to visit our new homepage, where we post about #proteostasis, current projects and #jobopportunities!
andreassonlab.com
English
AndréassonLab
374 posts
AndréassonLab
@AndreassonLab
We use yeast to understand the molecular mechanisms of cellular protein homeostasis. Account is run by members of the lab.
Stockholm, Sweden Katılım Ocak 2021
932 Takip Edilen1.1K Takipçiler
AndréassonLab retweetledi
From MBoC
Genetic inactivation of essential HSF1 reveals an isolated transcriptional stress response selectively induced by protein misfolding
Cells counteract stress by inducing adaptive transcriptional programs. Hsf1 in yeast is solely responsible
doi.org/10.1091/mbc.E2…
English
@_VerenaKohler Thanks! Took some time to get this out, Bpa crosslinking in human cells is not trival...
English
AndréassonLab retweetledi
Latest paper from my former lab- congrats, guys @AndreassonLab
Protein misfolding releases human Heat Shock Factor 1 (HSF1) from HSP70 latency control sciencedirect.com/science/articl…
English
Our new paper: Misfolded proteins activate HSF1 by releasing it from Hsp70. This has been clear in yeast for some time and we find that the mechanism is similar in human cells. sciencedirect.com/science/articl…
English
Very happy to share our latest findings: A novel chaperone – Chp1 – functions at the ribosomal tunnel to safeguard the biosynthesis of abundantly expressed eEF1A. Great collaboration with @BukauLab
@hauryliuk and many others! rdcu.be/dyFTI
English
AndréassonLab retweetledi
I'm so happy that the first paper from my PhD is finally published🙊. We define the tethers in the yeast vacuole-lipid droplets #membranecontactsite and their role in microlipophagy. Major thanks to all the people that contributed to make this story happen 😁
BüttnerLab@ButtnerLab
We are so proud to share the final version of our latest #MembraneContactSites story🎉, now in @Dev_Cell. We identify the LDO proteins and Vac8 as a tethering pair between the vacuole and lipid droplets (vCLIP) that mediates microlipophagy in starvation cell.com/developmental-…
English
Very happy to share our latest findings: A novel chaperone – Chp1 – functions at the ribosomal tunnel to safeguard the biosynthesis of abundantly expressed eEF1A. Great collaboration with @BukauLab @hauryliuk and many others!
rdcu.be/dyFTI
English
AndréassonLab retweetledi
We are so proud to share the final version of our latest #MembraneContactSites story🎉, now in @Dev_Cell. We identify the LDO proteins and Vac8 as a tethering pair between the vacuole and lipid droplets (vCLIP) that mediates microlipophagy in starvation
cell.com/developmental-…
English
AndréassonLab retweetledi
We are very proud to share our latest work describing the role of nuclear Hsp104 in protecting the translation machinery during quiescence
nature.com/articles/s4146…
English
AndréassonLab retweetledi
🎉We are thrilled to share our exciting new collaboration with @inada_lab and @jingdongcheng on how Otu2 recognizes and deubiquitinates 40S ribosomes after translation. Here is a thread with the most interesting findings:👇 #ribosome #ubiquitin #cryoEM
English
AndréassonLab retweetledi
We're happy to share a new paper (the 1st one!) from our SUMO project. A short summary follows. jbc.org/article/S0021-…
English
AndréassonLab retweetledi
Publication alert 🚨In our manuscript, we provide robust methods to biochemically and structurally analyze #mitoribosomes: Yeast Mitoribosome Purification and Analyses by Sucrose Density Centrifugation and Immunoprecipitation pubmed.ncbi.nlm.nih.gov/37166635/ @Ott_MitoLab #Mitochondria
English
AndréassonLab retweetledi
The TIM23 translocase of the inner membrane of mitochondria stabilizes PINK1 and thereby directly influences the distribution of Parkin. Beautiful mechanistic @CellReports study by Toshihiko Oka and Toshiya Endo relevant for mitophagy and parkinson. cell.com/cell-reports/f…
English
Genetic inactivation of essential HSF1 reveals an isolated transcriptional stress response selectively induced by protein misfolding | bioRxiv biorxiv.org/content/10.110…
English
AndréassonLab retweetledi
Check out this week's selection of publications on #MembraneContactSites!
biomed.news/bims-mecosi/20…
My favourite:
doi.org/10.1038/s41556…
Thanks to @Bims_BiomedNews for the pre-selection!
#ParkinsonsDisease #Neurodegeneration #MCS #Mitochondria #QualityControl #ESCRT
English
AndréassonLab retweetledi
IT'S FINALLY HERE! A story years in the making about how cells handle misfolded proteins in the nucleus and cytoplasm 1/12
#proteostasis #proteinfolding nature.com/articles/s4155…
English
Chaperone-directed ribosome repair after oxidative damage: Molecular Cell cell.com/molecular-cell…
English
AndréassonLab retweetledi
Back-to-back JBC papers! Happy to share another JBC paper @jbiolchem on the phase separation of bacterial nucleoid-associated proteins. A great collaboration with my departmental colleague, P. Guptasarma @guptasarma_p & his lab @pglab_iiserm @DBS_IISERM
doi.org/10.1016/j.jbc.…
Samrat Mukhopadhyay@SamratLabMohali
Happy to share our 4th paper in the Journal of Biological Chemistry (JBC) @jbiolchem (new role of ATP in yeast prion conversion). Congrats @SayantaIISERM (co-corresponding) @AnushaSarbahi (co-first) @_NehaPunia @AshishJ87810510 @AnamikaAvni @anuja_walimbe doi.org/10.1016/j.jbc.…
English
AndréassonLab retweetledi
The proteomic landscape of genome-wide genetic perturbations cell.com/cell/fulltext/…
English
AndréassonLab retweetledi
The phosphorylation status of Hsp82 regulates mitochondrial homeostasis during glucose sensing in Saccharomyces cerevisiae
#Proteostasis sciencedirect.com/science/articl…
English