Andres Floto

Massive thanks to everyone involved including Artur Rossi @theosanderson @TheMatuM Maria Ntemourtsidou, Vitor Mendes, Pedro Torres, @JulianParkhill @PeacockFlu @AndresFloto @flotocambridge

Our new preprint is now out We show that mutational signatures in influenza virus can identify transmission routes, host species and adaptive mutations for sustained respiratory transmission biorxiv.org/content/10.110…

Check out @doctorscm's Herculean effort to untangle periplasmic ion concentrations, metabolic activity and membrane permeability! #MembranePotential

We're seeking 2️⃣ research associates to join Professor @AndresFloto's lab @HLRI_Cambridge. You'll be part of a multidisciplinary team exploring antibiotic uptake, efflux & metabolism across multiple bacterial pathogens. Apply before 27 October: buff.ly/SqfTX3A

Thrilled to share our latest paper now out in @ScienceMagazine 🎉🤩 We investigated a century of plasmid evolution 🧬 and uncovered how they have adapted to the antibiotic era 💊 science.org/doi/10.1126/sc…

We're delighted that Felicity Crawshay-Williams (a final-year @MedCambridge PhD student) was presented with a PhD Student Award by the Cambridge Society for the Application of Research for her work tackling #AntimicrobialResistance. Read more: caths.cam.ac.uk/CSAR-2025

Pinte, @VallierLab et al. explore the role of EHF in lung homeostasis & disease by differentiating hiPSCs into lung airway epithelial cells & seeding them in an air–liquid interface culture system that mimics aspects of the respiratory tract environment. doi.org/10.1242/dmm.05…

Check out Maciek's tweetorial for our new bacterial protein language model Bacformer, creating a unified representation of bacterial genomes with links to pre-print, code, tutorials and blog post: x.com/wiatrak_maciej…

💥 Excited to introduce Bacformer 🦠 - the first foundation model for bacterial genomics. Bacformer represents genomes as sequences of ordered proteins, learning the “grammar” of how genes are arranged, interact and evolve. Preprint 📝: biorxiv.org/content/10.110… 🧵 1/n

Most importantly, huge shoutout to everyone who made this possible @aaron_weimann, @mariabrbic, @AndresFloto, @abelson_david and others! Thanks to them, the project was first and foremost immense fun! 🧵 15/n

So happy to share my work @jrpenades lab 🤩 We investigated the efficiency of HGT mechanisms in S. aureus🧬, finding that LT is the most efficient one, and that strains defective in immune systems🛡️act as gateways for inter-clonal complex HGT🔀 biorxiv.org/content/10.110…

Meet @Chaitanya_VS Growing up on a leprosy ward in India, he witnessed the impact of the disease. So he decided to do something about it! His latest research into leprosy has a secured £1.3m boost. Watch his story or bit.ly/4no3bQO read about the funding. @MedCambridge

One week left to join @AndresFloto's team as a Postdoctoral Research Associate to develop new antibiotics against mycobacteria using permeability-enabled fragment-based #DrugDiscovery. This 2-year position is based in @CambridgeBRC. 🧬Apply now: buff.ly/Bjy2gja

Hear more from our Professor Eoin McKinney, @AndresFloto & @MihaelaVDS on how we're unleashing the full potential of AI in health and medicine, and how @CC4AIM puts us in the perfect position to be leaders in the field⬇️ cam.ac.uk/opinion-ai-and… #ShapingAIForEveryone

Exciting PhD studentship opportunity on understanding chemical permeability to advance antibiotic drug discovery @flotocambridge jobs.cam.ac.uk/job/50800/. Combines experimental approaches with in silico screening and generative AI.

Let the best teachers guide your next steps on your AI Journey! Our #SummerSchool for AI in Medicine brings you top experts to share insights on AI-driven medicine, LLMs, decision support, & real-world impact! 📅 12-14 Sept 2025 Secure your spot today: vanderschaar-lab.com/cambridge-ai-i…

Thanks to the amazing @cazares_adr, @aaron_weimann, @AndresFloto, @BacPathLiv, Eleri and Martin 🙌

My first paper as corresponding author is out @PLOSBiology! 🤯 Super proud of my amazing collaborators @cazares_adr (co-corresponding), @cazares_dan, @NobregaFL and everyone else! (not in twitter) And so grateful to the fantastic editors and reviewers! journals.plos.org/plosbiology/ar…

We are very excited to announce our latest work on how MRSA conquers antibiotics. We show that high-level resistance to methicillin requires S. aureus to utilise an alternative mode of cell division to ensure its survival! @Sheffield_AFM @Olulana4 doi.org/10.1126/scienc…

Very excited to announce the first conference on Advancements of Microbiology, next April in Warsaw We have an exciting line up for the Pathogen Genomics forum including @AndresFloto @Lucy_Weinert @Chris3Ruis Registration and abstract submission advmicro2025.pl