DMM Journal

Join researchers working on #PediatricCancer at our Meeting this October at Nationwide Children’s Hospital, USA. Organisers: James Amatruda, Pratiti (Mimi) Bandopadhayay, Ana Banito & Elaine Mardis Register at bit.ly/3OCi1q9 Early-bird deadline: 19 June 2026

Head to @prelights website and read a preprint about changes in gut microbiome over the course of multiple sclerosis, chosen by Carole Djagang, Nour HAROUN, Phalica Georges and uMontreal Neuro preLighters. Prelight: bit.ly/4tFP63g Preprint: doi.org/10.64898/2026.…

Ana Banito is speaking on 'Somatic gene delivery for flexible in vivo modeling of pediatric sarcoma' at our Journal Meeting this October #DMM2026cancer Register to attend: biologists.com/meetings/dmm20… Early-bird deadline: 19 June 2026

DMM congratulates Francesca Giulia Urso (centre), from @reNEW_Global, winner of the DMM-sponsored poster prize at the latest advances in Latest Advances in Stem Cell-Based Disease Modelling and Drug Screening symposium.

The program for our @cclguk symposium, co-sponsored by @DMM_Journal, @NeuroblastomaUK and @ParseBio , on the developmental origins of paediatric cancer is now finalised (8th June, @TheCrick): cclg.org.uk/information-pr…

Bone‑marrow biopsies from severe aplastic anaemia patients showed increased nestin⁺ niches, supporting immune injury and maladaptive stromal remodelling as disease drivers and the importance of the marrow microenvironment. Beerlage, Drexler, Tzankov & co doi.org/10.1242/dmm.05…

A study in mice suggests that the Chiari II brain malformation, common in children with open spina bifida, develops as a secondary consequence of this neural tube defect. Maryam Clark, Andrew Copp & co Article doi.org/10.1242/dmm.05…

Head to our community website thenode.biologists.com for a weekend read: Some cancer drugs disrupt taste by changing the cells inside taste buds bit.ly/4t4tfSN @the_Node

Do you have a vision for a Workshop but don’t have the time to arrange the logistics or raise the funding? We'll provide all necessary support. Submit your idea to us in our annual call for topics. Deadline to submit your idea is 29 May. biologists.com/workshops/prop…

A CRISPR‑engineered #MouseStrain with a disrupted Il1a nuclear localisation sequence helps to investigate how nuclear trafficking shapes #inflammatory and #antiviral responses. @choyle22, David Brough, Gloria Lopez-Castejon & co @BIG_research Full paper doi.org/10.1242/dmm.05…

Seven patient‑derived #xenograft models of invasive lobular #cancer were developed and validated, featuring common alterations in PIK3CA (57%), CDH1 (57%), and TP53 (57%). Jagmohan Hooda, Jennifer Atkinson, Adrian Lee & co Full paper doi.org/10.1242/dmm.05…

A #zebrafish study shows that ctsz mutations disrupt #macrophage polarisation and #regeneration, suggesting that Ctsz modulates the inflammatory response to #injury and shapes regenerative outcomes. Bastos, Loynes, Speirs, Elks, Braga & co Full article doi.org/10.1242/dmm.05…

And check out the interview with the first author, Ana Filipa Castro To be honest, it wasn't a single person or specific moment that inspired me to become a scientist. My interest developed gradually [...]. Full interview doi.org/10.1242/dmm.05…

A #zebrafish model of spinocerebellar #ataxia shows that embryonic expression of the AUUUC repeat RNA disrupts axonal and synaptic development, impairing neuronal circuits and leading to adult motor dysfunction. Ana Castro, José Bessa Isabel Silveira & co doi.org/10.1242/dmm.05…

Check April preprint highlight by preLighter Hannah Pletcher: a study identifying 4,5‑DHHA as a potential biomarker for monitoring mitochondrial diseases affecting the respiratory chain. bit.ly/4tJjKJY doi.org/10.64898/2026.… @preLights

We are delighted to support @CRUK_SI Beatson International Cancer Conference 2026 ‘From Tumour Genesis to Metastasis: an immune perspective’. Don't miss the 1 May registration deadline.

To celebrate #WorldMalariaDay this Saturday, join us in revisiting our 2025 Special Issue on infectious diseases journals.biologists.com/dmm/issue/18/9. DMM is committed to supporting research that drives progress against infectious diseases.

Join researchers working on pediatric cancer at @DMM_Journal's Meeting this October at Nationwide Children’s Hospital, USA. Organisers: James Amatruda, Pratiti (Mimi) Bandopadhayay, Ana Banito & Elaine Mardis Register at bit.ly/3OCi1q9 Early-bird deadline: 19 June 2026

Check out a preprint chosen by preLighters C. Alves Conceição, M. Oliveira showing that bacterial amyloid‑like peptides can modulate Aβ aggregation linked to Alzheimer’s disease. PreLights: bit.ly/4cR8FjO Preprint: biorxiv.org/content/10.110… @preLights

This #EarthDay, let’s talk about how the environment influences our health. Read our mini‑focus issue on the effects of “forever chemicals” and the researchers tackling this challenge. journals.biologists.com/dmm/issue/18/11 Img from J. DeWitt Perspective on the concerns over ‘forever chemicals’