Javed Butler

Now in @JACCJournals a new analysis from the VICTOR trial examines the effect of vericiguat on recurrent heart failure hospitalizations and death in ambulatory HFrEF, highlighting the value of recurrent-event analyses for capturing overall disease burden. jacc.org/doi/10.1016/j.…

In the PolyHF trial, published in @NatureMedicine, we show that a once-daily polypill (metop + spiro + empag) outperformed enhanced usual care in HFrEF: ⬆️ LVEF (+3.3%) ⬇️ HF hospitalizations by 60% ⬆️ Adherence 🔗 nature.com/articles/s4159…

Great debate: medical treatment of #HFrEF will rely on four foundational drugs Pro—Con’ is timely and important to all cardiologists involved in the medical treatment of #HFrEF @SJGreene_md @JavedButler1 @ESC_Journals

Frustrated by the decline of thoughtful medical discussion online?! I've enjoyed the cardiology conversations @roondoctors Roon was built by doctors, for doctors and it shows Join the growing cardiology community on Roon: roon.com/doctors?utm_so…

🔥Hot of the press in EHJ🔥 Our Great debate: medical treatment of heart failure with reduced ejection fraction will rely on four foundational drugs academic.oup.com/eurheartj/arti… @ehj_ed @ESC_Journals @EJHFEiC @AmrAbdin10 @JavedButler1 @ShelleyZieroth @rudolf_deboer @DavidDuncker

📢 Simultaneous or rapid sequence #GDMTworks wins again in #HF This time w/ a polypill 🏆As routine approach, the #HF community must be willing to initiate & titrate more than one med at same time Slow 🐌#GDMT cannot keep up w pace of☠️ & 🏥 nature.com/articles/s4159…

Our new study in Eur Heart J: In pts with HFpEF and obesity, GLP-1 RA–induced weight loss was associated with improved invasive exercise hemodynamics @ambarish4786 @JavedButler1 @utswheart @UTSWCardfellow @UTSWMedCenter @ESC_Journals @ESC_Journals academic.oup.com/eurheartj/arti…

@robmentz @dranulala @DrMarthaGulati @HFSA @JCardFail @AndrewJSauer @ShashankSinhaMD @noshreza @mvaduganathan @JavedButler1 @lamcardio Nice article. The more we focus on underlying cause of pathology/ symptoms, the better. Same about symptoms related to CAD, a.fib, COPD, etc. Even adiposity-HFpEF perhaps is not a primarily a "failing heart" issue, and therefore evolving from the "HF" label may be best.

The language of "HFpEF mimickers" is often used - What does this actually mean?! Provocative piece helps to reframe this concept: "What Are HFpEF Mimics and What Are They Mimicking? Insights Into Our Conceptualization of HFpEF as a Disease" onlinejcf.com/article/S1071-…

Optimizing Care in Cardiovascular-Kidney-Metabolic Syndrome: Registry Data From the Cardiometabolic Center Alliance @DrBenzigerHeart @AndrewJSauer @JavedButler1 @Dr.dapo ahajrnls.org/4oWuGm0

A Contemporary Perspective on Acute Decompensated Heart Failure Classification: A State-of-the-art Review from an International Expert Group. doi.org/10.15420/cfr.2… Contributions from Baim faculty, @JavedButler1 and Dr. Mandeep Mehra. #BaimInstitute #Cardiology #HeartFailure

What Are HFpEF Mimics and What Are They Mimicking? Insights Into Our Conceptualization of Heart Failure With Preserved Ejection Fraction as a Disease. doi.org/10.1016/j.card… Contributions from Baim faculty, @lamcardio and @JavedButler1. #BaimInstitute #HeartFailure

Mens Health Month healthinsight.ca/mens-healthcar… @DLBHATTMD @JavedButler1 @DrMarthaGulati @UofT @cscs_sccc @UofTSurgery @shubhkpatel @NitishKDhingra

Today: EASi-KIDNEY=6609 participants=EMPA-KIDNEY! Brilliant patients, clinics and hospitals from 500+ sites are growing larger renal trials & wider collaborations. 🙏 🙏 🙏 🤩 Just a few more thousand volunteers patients needed…..

💊 SGLT inhibitors for HF 🚀 Ultra-rapid clinical benefits ❤️‍🩹 Benefits >>potential risks across the EF spectrum ⬇️ CV☠️/HF🏨 ⬆️ HRQoL 🪎 Amazing value $60 a year in med costs ▶️ $2500 a year in ⬇️🏨s savings ✅ Start now doi.org/10.1016/j.jchf…

Albuminuria and heart failure. doi.org/10.1093/eurhea… Contributions from Baim faculty, @JavedButler1. #BaimInstitute #ClinicalResearch #Cardiology #HeartFailure

Want to reverse the “reversal” in HF related mortality temporal trends? ARNI+BB+MRA+SGLT2i expeditiously in all eligible patients with HFrEF ➡️ Rapid ⬇️ HF related ☠️s Rapid ⬇️ in HF 🏨s and re-🏨s Rapid ⬇️ in net healthcare expenditures for HF

The strongest determinant of long-term GDMT adherence is in-🏨 initiation The 🔑 to optimized outcomes in HF Independent of age, sex, race-ethnicity, comorbidities, insurance doi.org/10.1161/jaha.1…

🫀 Is left ventricular non-compaction (LVNC) a distinct cardiomyopathy or the extreme end of a trabeculation spectrum? The first article in our special issue, The Many Faces of Cardiomyopathies, reviews the evolving evidence on LVHT/LVNC and proposes a pragmatic approach integrating imaging, genetics, and clinical context. Key takeaway: prognosis is driven less by trabeculation itself and more by ventricular function, myocardial substrate, and arrhythmic burden. link.springer.com/article/10.100… #HREV @GianluSava @PolovinaMarija @GMCRosano @JavedButler1 @NicolasGirerd

✅Albuminuria and Heart Failure- published in @ESC_Journals 📌UACR screening is important for early detection, risk stratification and intervention to improve outcomes @JavedButler1 academic.oup.com/eurheartj/adva…