Anne Calvez

Special issue on "The cancer-immunity cycle," a concept first introduced by Mellman & Chen in 2013 that provided a framework to understand anti-cancer immunity | Seven articles discussing progress & advances in the field & highlighting key challenges #cancerimmunitycycle cell.com/immunity/issue…

Tertiary lymphoid structures and B cells: An intratumoral immunity cycle: Fridman and colleagues review the role of tertiary lymphoid structures in the generation of T and B cell immunities in the context of cancer. Integrating insights from basic research and the clinic, the authors propose a role for antibodies in a loop that amplifies anti-tumor immunity within the tumor. authors.elsevier.com/a/1hkjD3qNrUu3…

Happy to share our review in @ImmunityCP describing how TLS participate in the establishment of an intratumoral immunity cycle, increasing sensitivity of tumors to immunotherapy ⬇️ @sautesfridm @fridmanwh @IsaienceHdz @MaximeMeylan and Guilhem Pupier @CRCordeliers

Fascinating @Nature paper that suggests the presence of tertiary lymphoid structures in advanced #softtissuesarcomas is a potential predictive #biomarker to improve patients’ selection for pembrolizumab treatment. go.nature.com/3akn3TY #spatialbiology #weekendreading

[Colloque « Cancer et immunité » au Collège de France @cdf1530] Le colloque #Cancer et #immunité réunira pendant deux jours les meilleurs spécialistes mondiaux du domaine.