ARRIGE

Our new President Hervé Chneiweiss has prepared this welcome message for ARRIGE members and associated colleagues. It includes his vision for the future of our association. arrige.org/vision-for-the…

We have released the 2025 ARRIGE annual meeting summary and statement. You can download it and read it from @ArrigeOrg web site: @LluisMontoliu @MartinaCrispo arrige.org/documents/

If you want to know the meaning and fears behind the saying: “opening the Pandora box” just read this article in @Nature about a company called Manhattan Genomics run by someone called Biotech Barbie. She is planning to edit human embryos, and is not alone nature.com/articles/d4158…

@UrnovFyodor @kiranmusunuru Today, 29 Oct, we will continue our annual meeting with yet another interesting session on “Ethical and Policy Challenges: Access, Incentives, IP, Responsibilities” with Julian März, Pawel Lukow, Paul Aliu and Daima Bukini. We’ll finish with a roundtable. arrige.org/portfolio/2025…

Oir first panel is on “Technicalities” with @UrnovFyodor @kiranmusunuru and Marina Cavazzana

We are starting our 2025 ARRIGE annual meeting focused on “access and affordability of gene therapies: challenges for genome editin” both online and in person in Strasbourg. Keynote speaker is Alta Charo arrige.org/portfolio/2025…

Register for the 2025 @ArrigeOrg annual meeting devoted to discuss accessibility and affordability of the novel #CRISPR based gene therapies. In Strasbourg (France) hybrid format, both in-person and online: 28-29 Oct. Free for ARRIGE members. Register at⬇️ arrige.org/portfolio/2025…

Today we will celebrate the 4th @ArrigeOrg Albrecht Müller webinar online, this time devoted to #RNAediting in collaboration with @MSCActions #ROPES Starting at 14:00 Paris/CET arrige.org/portfolio/4th-…

The Montoliu’s lab and @CNB_CSIC @CSIC Mouse Embryo Cryopreservation facility attending the 19th @ISTT_TG #TT2025 meeting at @ETH_en in Zürich (Switzerland). Catching up with many old friends and colleagues in the transgenic animal technologies field. tt2025.org

Interested in RNA editing? Then you should attend the 4th Albrecht Müller ARRIGE webinar, on 7 May, at 14:00-17:00 Paris/CET on “Editing RNA or DNA: the great challenge” organized along with @MSCActions #ROPES Participation is free, registration required arrige.org/portfolio/4th-…

Following the publication of this article by the team of @juliansavulescu in @Nature we have just released a statement on heritable polygenic editing prepared by the ARRIGE Board: ⬇️ arrige.org/documents/

@Nature We, from @ArrigeOrg, the association for responsible research and innovation in genome editing, promoting the responsible use of genome editing tools, have also released a statement where we discuss and reject the proposal of heritable polygenic editing. arrige.org/wp-content/upl…

Furthermore, potential health benefits and disease resistance traits associated with genetic variants do not strictly correlate with the expected behaviors, rather with certain probabilities. A critical commentary has also been published in @Nature nature.com/articles/d4158…

What was wrong in 2018 continues being wrong in 2025. Hence, pretending to edit the human genome at multiple genes only multiplies the risk of unwanted editions at selected locations and elsewhere. It is simply unsafe and reckless to suggest multiple gene editing on human embryos

In 2018 the irresponsible experiments done by He Jiankui showed the world why it was a bad idea editing one gene on human embryos. Now, a team of Australian scientists led by P. Visscher and J. Savulescu speculates in @Nature on heritable polygenic editing nature.com/articles/s4158…

Strong statement on polygenic editing Nature paper from ARRIGE.

This follows a previous similar study, where we had the opportunity to participate, describing several resurrected #CRISPR Cas9 nucleases ranging from ~37 through 2.600 My ago. This collaborative study about Cas9 ancestors was published in @NatureMicrobiol nature.com/articles/s4156…

The Raúl Pérez Jiménez lab at @CICbioGUNE did it again, after resurrecting Cas9 ancestors in 2023, @YleniaJabalera et al they just report a new resurrected Cas12a CRISPR nuclease ancestor that could have existed ~3.000 My ago. Published in @NatureBiotech nature.com/articles/s4158…

Thrilled to see the special issue on "CRISPR Trials" at @CRISPRjournal! In addition to many papers of great topicality, you can find our open-access Perspective with @LluisMontoliu and @idemiguelb on the affordability problem of CRISPR therapies. Link👇 liebertpub.com/doi/10.1089/cr…