Aude Dorison

Thrilled to announce the publication of this research paper on NPHS2 variants and their impact on Podocin trafficking unraveling new insights on steroid-resistant nephrotic syndrome pathophysiology using iPSC-derived kidney organoids. @MCRI_for_kids #kidney #organoid #stemcells

Pleased to be sharing this chapter written with Nils @LindstromLab for Current Topics in Developmental Biology! Here we dive into how #nephrons establish proximal-distal patterning during #KidneyDevelopment & what this means for #StemCell-derived nephrons: authors.elsevier.com/a/1kWLp_1cBJyr…

We are hiring! Postdoctoral position available in the Little Group, Copenhagen University. We study kidney organoids using microscopy, transcriptomics, bioinformatics, bioengineering... all the fun stuff!!! employment.ku.dk/all-vacancies/…

@holly_voges @heartfoundation Congratulations Holly!!! 🎉👏

Thank you @heartfoundation !

First ASN since 2015! Different year, same place #SanDiego Very excited to be here and looking forward to enjoying fantastic science! #KidneyWk #kidneyweek2024 #KidneyWk2024

@KidneyCathy @RCPI_news Congratulations Cathy 🎉🎉

Absolutely thrilled to receive a Fellowship of the @RCPI_news 🎉 Such a beautiful ceremony in an incredible building. So proud to be part of this amazing Irish medical community! 🇮🇪 #RCPI #IrishMedicine 🌟

Very excited to be a finalist in the #reNEW ARTxSCIENCE 2024 image competition. Many thanks to everyone who voted for my submission. Congratulations to the other finalists who submitted fantastic images. I am glad #kidney share the spotlight with you today! 🔬✨

Congrats to #MCRI's Dr Kiymet Bozaoglu who has received a New Investigator Award to examine the impacts of #NF1 on brain function. NF1 causes various benign tumours and is linked to #ADHD & #autism. | @Kiymet_b @DeptofDefense ➡️ direc.to/mgXz

#ARTxSCIENCE 2024: Discover the power of science combined with artistic expression and learn about the potential of stem cell research to transform the lives of people. Help up find a winner of the best fusion of #ARTxSCIENCE on lnkd.in/gAv_Yzyf #Kidney Glomeruli on Fire’ #Kidneydisease is often viewed as a disease of adults, but 1 in 15,000 children present with kidney disease as a result of inherited #gene variants. The research of Al Dr Aude Dorison and her team aims at increasing knowledge of genetic kidney disease in children and identify novel and effective therapeutic strategies. Children with changes in specific genes can present with #kidneyfailure in the first few years of life and no other treatment than dialysis or transplantation currently exists. By generating #minikidney from patient-derived #stemcells, we are able to improve our understanding of the cellular and molecular mechanisms driving the disease. This provides us with an opportunity to design therapies specifically correcting the defects identified. The team has found the underlying cause of one of the most common forms of genetic nephrotic syndrome. They have also developed a miniature stem cell-based model of the disease with which we will screen thousands of compounds looking for those able to correct the molecular problem. Here we see a glomerulus in a stem cell-derived mini-kidney. The cells lighting up in the centre are podocytes, a key cell type for the filtration of the blood into the urine. @MCRI @LUMC @UCPH Submission by Al Dr Aude Dorison, PhD, (Senior Research Officer), Ms Rachel Lam and Ms Irene Ghobrial, Prof Melissa Little Lab, #reNEWMelbourne, Australia

Great to see this paper out now in JVI @JVirology: using stem cell-derived enhanced kidney organoids to gain further understanding of SARS-CoV-2 entry mechanisms in human kidney cells @MCRI_for_Kids @TheDohertyInst (journals.asm.org/doi/10.1128/jv…)

@JamesMc2327 @heartfoundation @PorrelloER @DaveElliott_1 Congratulations James! This is absolutely fantastic 🎉

Over the moon that I've been awarded a Heart Foundation Future Leader Fellowship! A massive thank you to @heartfoundation and their donors for all that they do for cardiovascular health in Australia! Also to my great mentors @PorrelloER @DaveElliott_1! heartfoundation.org.au/media-releases…

.@JMVanslambrouck & team from #reNEW Melbourne @MCRI_for_kids have published an advanced way to create #stemcell derived kidneys with improved proximal tubules in @NatureProtocols, to accelerate progress towards treatment for #CDK in adults and children. renew.science/stories/advanc…

Our #reNEW #Melbourne team is looking for a Research Assistant / Research Officer in the Bioinformatics Facility, based in the @MCRI_for_kids Transcriptomics and Bioinformatics group 👇 renew.science/jobs/research-…

Want to hear about what MCRI researchers have in store for our upcoming Meet the scientists event? Head to @MCRI_for_kids Instagram page to find out! @kidney_tom @kynanlawlor #kidney #kidneydisease #kidneyorganoids #stemcells #childhealth instagram.com/reel/Ct_Frc1rV…

🫘👩‍🔬Join Prof Melissa Little & a panel of MCRI researchers to explore the latest advancements in #kidney stem cell research. Engage with scientists & share your experiences as a patient. #MeetTheScientists #KidneyResearch #StemCells Register for FREE➡️eventbrite.com.au/e/meet-the-sci…

@inesmpsan @reNEW_Global It was great to have you joining the team for a month Ines. All the best back to Copenhagen and looking forward to continuing our collaboration 😃

Saying goodbye to Melbourne, ready to head back to my base ground in Copenhagen and continue sciencing - now with a broader skillset and some stories to tell. It was a huge opportunity to come and train here. A huge acknowledgment to both the Little Labs and to @reNEW_Global.

@LiddelowSA Western blot zoom meeting? 🤔😆

does it need saying? ... don't do this:

Excited for this opportunity to present our latest research and engage with patients. Looking forward to this event! #kidney #stemcellresearch #patientengagement

@holly_voges @CellReports @MCRI_for_kids @reNEW_Global Congrats Holly and team! Well done! 👏🎉

It’s finally out! Thanks to the team that pulled this all together. cell.com/cell-reports/f… @CellReports @MCRI_for_kids @reNEW_Global

When your bestie is just incredibly talented! Congratulations @JMoreau83 !!! 🎉

MCRI is grateful to have received #MRFF funding & we’re highlighting some of these funded #research projects & clinical trials in a series of #MRFFinaMinute 📹 on #MRFFMondays. This week we feature Prof Melissa Little’s research. 🔗mcri.edu.au/news-stories/m… youtu.be/Dj0eNJG23ys