David Bartlett, PhD

All systems go. Ready to begin a full-on CLL scientific day in central London. #CLL

Researchers explored whether a quick, 30-second handgrip task could capture subjective fatigue, the kind you notice during training, work, or daily life. 👉 Swipe to test your intuition. Would you expect a simple strength task to tell the full story? #AEHS #Exercise #Fatigue

Thank you to everyone who joined us at the Purple Ball! It was a wonderful evening with many new faces, and together we raised £11,000 for Topic of Cancer. We’re so grateful for your support and generosity. 💜 #PurpleBall #TopicOfCancer

Nature research paper: Tumour-reactive heterotypic CD8 T cell clusters from clinical samples go.nature.com/4oTSupN

Online Now: A longitudinal single-cell atlas to predict outcome and toxicity after BCMA-directed CAR T cell therapy in multiple myeloma dlvr.it/TPRhN2

We’re so grateful to everyone who gets involved and supports Topic of Cancer - from runners and volunteers to donors and event guests. Together, we’re funding research that gives hope. Read more about Topic of Cancer on our website here: topicofcancer.org.uk

Our free ToCFit exercise sessions help cancer patients and survivors build strength and confidence in a relaxed, friendly environment. No pressure, just support. For more details, email chair@topicofcancer.org.uk

Every donation helps us fund innovative immunotherapy research and support people living with cancer. It’s your generosity that drives change. topicofcancer.org.uk/donate/ #TopicOfCancer #ImmunotherapyResearch #CancerTreatmentResearch #GuildfordCharity

Brilliant to see our work @UniSurreyBioSci and @DukeCancer in the #CLL UK guidelines for the first time advising physical activity and exercise for patients with chronic lymphocytic leukaemia 😀. #exerciseoncology @BrJHaem onlinelibrary.wiley.com/doi/10.1111/bj…

We’re so proud of Therese, who has completed her 10K run to raise funds for Topic of Cancer! As an oesophageal cancer patient, Therese has personally benefitted from the research carried out by the Oncology Research Team, including the exercise-based studies supported ... 1/2

@nanoha1995 I hope it will be part of the cancer treatment plans, but in the UK, it will come down to available money 😞.

@Bartlett_Lab Incredible progress! Do you think exercise will soon be integrated as a standard part of colon cancer treatment plans, or will it remain more of a supportive lifestyle recommendation?

bbc.co.uk/news/articles/… Great to finally see this out, but @CR_UK nailed it for the UK-get it sorted @wesstreeting "This trial has the potential to transform clinical practice, but only if health services have the necessary funding and staff to make it a reality for patients"

@yujin_evelyn @EllieeMiles @e_JHaem It's most likely people will have a better quality of life improvement if they can do physical activity they really like doing.

@Bartlett_Lab @EllieeMiles @e_JHaem This is really encouraging data! Do you think different types of physical activity have varying impacts on improving quality of life and reducing symptoms for people living with CLL.

Great work from my PhD student @EllieeMiles on her 1st of many papers on #CLL in @e_JHaem. She shows that being physically active with CLL is associated with better QoL & reduced symptoms of CLL, including fatigue, pain, and physical limitations. onlinelibrary.wiley.com/doi/10.1002/jh…

Cool presentation that shows that in 75% of pts with IgM and CLL, the CLL is producing the IgM (I.e. the MGUS is not a separate process) #iwCLL2025

Effects of lactate concentration on T‐cell phenotype and mitochondrial respiration - Cho - 2025 - Physiological Reports - Wiley Online Library physoc.onlinelibrary.wiley.com/doi/10.14814/p…

🫁 New research: Just 10 weeks of training can boost lung function in kids with cystic fibrosis. ✅ Endurance ✅ Resistance ✅ Best of all? Concurrent training 💪 Improved pulmonary function & quality of life. Exercise is medicine. #CysticFibrosis #PedsCare #ClinicalTrials

'Exercise during chemotherapy may help immune cells fight cancer' Learn more about this research, which Topic of Cancer has proudly supported, a first-of-its-kind pilot study from @UniOfSurrey and @RoyalSurrey medicalxpress.com/news/2025-06-c…

Honoured to present our from the i3 collaborative w/ @UTSEngage work using #DigitalTech to support independence & wellbeing in #AdvancedCancer Great questions & discussions, so grateful to share & learn w/ the #MASCC community! #DigitalHealth #CancerCare #SupportiveOncology

Presented at #EHA2025: Among patients with chronic lymphocytic leukemia, undetectable MRD and progression-free survival were more common with ibrutinib–venetoclax than with ibrutinib alone or chemoimmunotherapy, with benefits sustained at 5 years. Full FLAIR phase 3 trial results: nej.md/3SMNdC4  @eha_hematology

CLL13 longer follow up - huge study and great presentation. Though GIV is superior, I would not use as SOC since the duration of therapy is longer (range 12-36 months) than ven/obi which is still quite excellent (and always 1 yr). And yes MRD still matters! #EHA25 #EHA2025