BasedBidoof

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BasedBidoof

BasedBidoof

@BasedBidoof

🇺🇸 RightToRepair | Fixer, Maker, Shitposter | Can't stop the signal | I don't get paid from twitter (might be cringe)

Tampa, FL Katılım Ekim 2016
5.4K Takip Edilen927 Takipçiler
BasedBidoof
BasedBidoof@BasedBidoof·
@bryan_johnson Make sure you pray to god while on dmt, it was a revelation, an epiphany
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Bryan Johnson
Bryan Johnson@bryan_johnson·
Livestreaming 5-MeO-DMT this weekend… what should I expect?
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uwo's lab | the funny science man
IN 90 MINUTES (6PM EST) we're gonna be testing a theoretical speaker build from the gigabrains on the DIYaudio subreddit, the Shitwoofer
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BasedBidoof retweetledi
ACTIONMAN
ACTIONMAN@Ac7ionMann·
When I leave hotels I never “checkout”. I just walk right out every time. If they need to find the keys they can find them. And I also feel bad looking them in the eyes knowing I made a huge mess and trashed the room. Out I go.
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Bryan Johnson
Bryan Johnson@bryan_johnson·
Two doses of magic mushrooms degraded my sperm count from the 99.6th percentile to the 77.7th. This may be a first-in-human observation. Context: we ran the most quantified magic mushroom (psilocybin) experiment ever conducted. We were asking if psilocybin is a longevity therapy. After seeing the data, we think it is (see reply post for the experiment summary). Also, like most things biology: the results are complicated. My data suggests that the magic mushrooms (psilocybin) negatively impacted my fertility markers. Before the first psilocybin dose my motile sperm count was at 99.6th percentile for men under 25 years of age, it dropped to 77.7% and partially recovered to 89.3% following the first dose, and second doses, compared to the same age cohort (numbers compare similarly to my age cohort as well). 3 days following my second dose (first dose 25 mg, second dose 28 mg) . Motility: dropped 51% . Total count: almost unchanged, dropped by 2% . Total motile count: dropped 52% . Normal morphology: dropped by 50% 20 days post 2nd dose, the pattern continued, with typical latent effects on total sperm counts Motility: recovered back to -2% of pre-psilocybin baseline: . Total count: dropped by 38%, latent effect. . Total motile count: remained inhibited at -39% of pre-psilocybin baseline, (despite motility normalizing, due to the total count drop) . Morphology normalized to -10% of baseline levels. Reduction in free testosterone might have contributed to the effect. While total serum testosterone increased by 30% 3 days following the 2nd dose (neither FSH or LH were meaningfully affected either), and continued to be at 11% above baseline, SHBG increased by 37%, SHBG binds testosterone and reduces its bioavailability and activity. My free testosterone (direct) showed 24% and 23% drops at 3 and 20 days post 2nd dose. In light of the neuroplastic, well-being, brain reset, and systemic metabolic and anti-inflammatory benefits, the trade-off is probably worth it. Especially considering that the magnitude of inhibition has no meaningful effect on actual fertility (total motile counts above 50 million are still on the safe side). This is a first-in-human observation, to our knowledge there is no published human clinical study demonstrating that psilocybin diminishes male fertility markers. General mechanistic evidence exists for recreational and psychoactive drugs possibly inhibiting fertility markers due to their effects on the hypothalamus-pituitary-adrenal axis and general hormonal reset.  Yet no direct evidence for psilocybin or other similar psychedelics inhibiting fertility markers exist. A potential mechanism for the immediate inhibition of motility could involve direct serotonergic signaling in sperm. Human sperm express multiple serotonin receptors, including 5-HT2A, and one recent study found that a 5-HT2A antagonist reduced sperm motility, suggesting that 5-HT2A may regulate motility. Psilocybin is known to bind 5-HT2A with high affinity.
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BasedBidoof
BasedBidoof@BasedBidoof·
@zachbussey Sadge no more spamming horse during the middle of an important event
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Zach Bussey 🇨🇦
Zach Bussey 🇨🇦@zachbussey·
Twitch is deprecating Combos at the end of March 2026.
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Noah Ryan
Noah Ryan@NoahRyanCo·
Move into new rental. Nose gets stuffed. Then vision gets blurry. Then words start slipping my tongue. Peek in the mirror and I look hungover. Feels like I got a concussion. Look in the cabinets, mold everywhere. Florida.
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Remedial Rifleman
Remedial Rifleman@Dead_z3ntropy·
Well, only for those not hung up on being pedantic... monochrome printers use mark intensity modulation aka "inking" Lazer or otherwise. It's essentially a noise pattern that has the time and date of print and serial number of the printer embedded as coded patterns. As for required laws, it's buried layers deep in regulations for devices to be sold Kinda like "you'll fail some other bullshit contrived test if your [thing] doesn't do [stuff], and will continue to fail no matter what."
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BasedBidoof
BasedBidoof@BasedBidoof·
@brian_eno_69 Ineffective the demons can still get you from the underside. Better to be suspended by a chain and over a fire so you're completely engulfed, purging them from your aura
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alexandra
alexandra@brian_eno_69·
i need to go to kazakhstan so that this woman can set me on fire in her apartment and cleanse me
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Elon Musk
Elon Musk@elonmusk·
@Dan16676935420 To prevent spam bot attacks, the dislike button will be for subscribers/verified accounts only
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dan
dan@Dan16676935420·
Very excited for the dislike button. Especially since X is such a positive, uplifting platform full of sane people and little to no bots. I literally can’t imagine it going wrong.
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BasedBidoof
BasedBidoof@BasedBidoof·
@georgia_bm_ How else would the criminals meet up the gangsters and politicians? I just know they’re going to use this as america bad propaganda in the future, look aus got rid of it and nothing happened!!! (censored free speech)
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Georgia Bennett-Murphy
Georgia Bennett-Murphy@georgia_bm_·
BREAKING: Australia’s High Court has struck down the use of ankle bracelets and curfews to monitor asylum seekers released from immigration detention, even where there’s a risk a serious offence would be committed. This includes murder, child sexual assault, human trafficking and family violence.
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BasedBidoof
BasedBidoof@BasedBidoof·
@Rank1Apples Same-well not fondue group. I tried give them so much evidence, trying to make them understand the flaws in their arguments. In the end there’s no helping someone understand something they don’t want to understand. Horse drinking water meme
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fascist.eth
fascist.eth@0xfascistx0·
Oh I also quit all my medications Antidepressants Everything I'm completely sober except sometimes I take half a deep web Adderall XD
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fascist.eth
fascist.eth@0xfascistx0·
So far this year I've quit - smoking cigs - smoking vape - smoking weed - eating fast food -drinking coffee Never thought I'd do any of this lol.
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Tropah
Tropah@TropahPalm·
🚨 Ac7ionMan started nodding off while having dinner at a fancy restaurant and had to immediately be taken home... His friends and viewers don't know what to do anymore as this is starting to happen more frequently... ☹️
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EducatëdHillbilly™
EducatëdHillbilly™@RobProvince·
Putting the trim back on and I’m just now realizing the drivers door trim ain’t right. 😑
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BasedBidoof
BasedBidoof@BasedBidoof·
@HankVenture5 if that guy didn’t let it in, would it just sit at the green light waiting?
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