BasedBidoof

@bryan_johnson Make sure you pray to god while on dmt, it was a revelation, an epiphany

Livestreaming 5-MeO-DMT this weekend… what should I expect?

@uwutoowo1 I wonder what frequency helps ease constipation

IN 90 MINUTES (6PM EST) we're gonna be testing a theoretical speaker build from the gigabrains on the DIYaudio subreddit, the Shitwoofer

Anybody that thinks this footage was faked in the early 70s is not credible

@Ac7ionMann I bet you don't return shopping carts either

When I leave hotels I never “checkout”. I just walk right out every time. If they need to find the keys they can find them. And I also feel bad looking them in the eyes knowing I made a huge mess and trashed the room. Out I go.

@bryan_johnson @FrenlyOfficer Nice data! So just get sober 6 months before procreation

Two doses of magic mushrooms degraded my sperm count from the 99.6th percentile to the 77.7th. This may be a first-in-human observation. Context: we ran the most quantified magic mushroom (psilocybin) experiment ever conducted. We were asking if psilocybin is a longevity therapy. After seeing the data, we think it is (see reply post for the experiment summary). Also, like most things biology: the results are complicated. My data suggests that the magic mushrooms (psilocybin) negatively impacted my fertility markers. Before the first psilocybin dose my motile sperm count was at 99.6th percentile for men under 25 years of age, it dropped to 77.7% and partially recovered to 89.3% following the first dose, and second doses, compared to the same age cohort (numbers compare similarly to my age cohort as well). 3 days following my second dose (first dose 25 mg, second dose 28 mg) . Motility: dropped 51% . Total count: almost unchanged, dropped by 2% . Total motile count: dropped 52% . Normal morphology: dropped by 50% 20 days post 2nd dose, the pattern continued, with typical latent effects on total sperm counts Motility: recovered back to -2% of pre-psilocybin baseline: . Total count: dropped by 38%, latent effect. . Total motile count: remained inhibited at -39% of pre-psilocybin baseline, (despite motility normalizing, due to the total count drop) . Morphology normalized to -10% of baseline levels. Reduction in free testosterone might have contributed to the effect. While total serum testosterone increased by 30% 3 days following the 2nd dose (neither FSH or LH were meaningfully affected either), and continued to be at 11% above baseline, SHBG increased by 37%, SHBG binds testosterone and reduces its bioavailability and activity. My free testosterone (direct) showed 24% and 23% drops at 3 and 20 days post 2nd dose. In light of the neuroplastic, well-being, brain reset, and systemic metabolic and anti-inflammatory benefits, the trade-off is probably worth it. Especially considering that the magnitude of inhibition has no meaningful effect on actual fertility (total motile counts above 50 million are still on the safe side). This is a first-in-human observation, to our knowledge there is no published human clinical study demonstrating that psilocybin diminishes male fertility markers. General mechanistic evidence exists for recreational and psychoactive drugs possibly inhibiting fertility markers due to their effects on the hypothalamus-pituitary-adrenal axis and general hormonal reset.  Yet no direct evidence for psilocybin or other similar psychedelics inhibiting fertility markers exist. A potential mechanism for the immediate inhibition of motility could involve direct serotonergic signaling in sperm. Human sperm express multiple serotonin receptors, including 5-HT2A, and one recent study found that a 5-HT2A antagonist reduced sperm motility, suggesting that 5-HT2A may regulate motility. Psilocybin is known to bind 5-HT2A with high affinity.

@fleshsimulator >plagiarized >obviously transformative

@zachbussey Sadge no more spamming horse during the middle of an important event

Twitch is deprecating Combos at the end of March 2026.

@elonmusk WEEBSDETECTED

Try Grok Imagine Chibi template. Super cute!

@NoahRyanCo Check your ac unit too cuh that shit is molded

Move into new rental. Nose gets stuffed. Then vision gets blurry. Then words start slipping my tongue. Peek in the mirror and I look hungover. Feels like I got a concussion. Look in the cabinets, mold everywhere. Florida.

@Dead_z3ntropy @Tubbymcwub @Punk8958 @uncledoomer Cool

Well, only for those not hung up on being pedantic... monochrome printers use mark intensity modulation aka "inking" Lazer or otherwise. It's essentially a noise pattern that has the time and date of print and serial number of the printer embedded as coded patterns. As for required laws, it's buried layers deep in regulations for devices to be sold Kinda like "you'll fail some other bullshit contrived test if your [thing] doesn't do [stuff], and will continue to fail no matter what."

there really is a "fix everything right now" button for buying a printer and its been the same for 20 years

@sug4rf4iryy Stockholm syndrome

@brian_eno_69 Ineffective the demons can still get you from the underside. Better to be suspended by a chain and over a fire so you're completely engulfed, purging them from your aura

i need to go to kazakhstan so that this woman can set me on fire in her apartment and cleanse me

@walterwhitepill Minecraft skyblock

Optimal arena to drop homeless people with melee weapons for a Pay-Per-View event

@elonmusk @LattinaBrown @Dan16676935420 reddit alert

@Dan16676935420 To prevent spam bot attacks, the dislike button will be for subscribers/verified accounts only

Very excited for the dislike button. Especially since X is such a positive, uplifting platform full of sane people and little to no bots. I literally can’t imagine it going wrong.

@georgia_bm_ How else would the criminals meet up the gangsters and politicians? I just know they’re going to use this as america bad propaganda in the future, look aus got rid of it and nothing happened!!! (censored free speech)

BREAKING: Australia’s High Court has struck down the use of ankle bracelets and curfews to monitor asylum seekers released from immigration detention, even where there’s a risk a serious offence would be committed. This includes murder, child sexual assault, human trafficking and family violence.

@Rank1Apples Same-well not fondue group. I tried give them so much evidence, trying to make them understand the flaws in their arguments. In the end there’s no helping someone understand something they don’t want to understand. Horse drinking water meme

I've lost friends over flat earth. Like I got disinvited from our friend group fondue over it.

@0xfascistx0 W recovery arc

Oh I also quit all my medications Antidepressants Everything I'm completely sober except sometimes I take half a deep web Adderall XD

So far this year I've quit - smoking cigs - smoking vape - smoking weed - eating fast food -drinking coffee Never thought I'd do any of this lol.

@thepowerofmyth1 @_broken_clock @Ac7ionMann @TropahPalm obviously not but try praying on dmt and experience the revelation

@BasedBidoof @_broken_clock @Ac7ionMann @TropahPalm 😆 this ain't 2019 lil bro. Nobody thinks Dmt elves are God anymore

🚨 Ac7ionMan started nodding off while having dinner at a fancy restaurant and had to immediately be taken home... His friends and viewers don't know what to do anymore as this is starting to happen more frequently... ☹️

@RobProvince wrong side?

Putting the trim back on and I’m just now realizing the drivers door trim ain’t right. 😑

@HankVenture5 if that guy didn’t let it in, would it just sit at the green light waiting?