BiotechObserver

A $SRPT timeline for the aspiring biojournalist

@tyleraloevera How does being a recipient, or the largest recipient, of aid contradict being an ally? You don't do logic very well, huh? Honestly man shove the american dollars up your ass and stop restraining our military. Then see what happens to your precious arab and Fakestinian friends.

How exactly is Israel our greatest ally? Specifically, what have they done to earn that title? Israel has not deployed troops alongside US forces in any conflict since its founding in 1948. Israel is by far the single largest recipient of American foreign aid in our history. Adjusting for inflation, US aid to Israel from 1951 to 2022 totaled $317.9 billion, making it the largest recipient of American foreign aid since World War II. Why don't we worry about fixing problems for everyday Americans instead of paving their streets with American tax dollars?

@AppleHelix @Biohazard3737 Again we're going back to the global warming nonsense? Haven't we moved on from that at this point?

@Biohazard3737 1000x more energy usage means how much global warming?

This guy has been quoting cases like this all day, and it is truly staggering how many there are. The US justice system went completely off the rails, and violent criminals face no consequences anymore

@David5913834377 @RedPillSayian Wow another Chapter in the book of "Everything I personally enjoy &spend money on is actually bad &the Jews' fault!" (So if it's bad, why are u spending your money on hip hop turning it into a multi-billion dollar industry, & why do u like it so much?) You should thank these Jews

@RedPillSayian What if black “culture”, as in rap culture, is merely pushed on the masses to degrade and bring down society, in an effort to enslave the masses in poverty, disinterest in education, single parenthood, and other detractors that benefit those truly in power? Who produces it all?

Myron and Sneako talks about Chud the Builder and the problems in the black community 🫣 “It’s j*ws thats really been pimping your dumbasses out”

@bren45000 How does the law work?

Chud the builder is looking at 20+ years in prison. All of you angry white “patriots” who defended this guy and got SO MAD at me for stating that Chud’s self-defense claim was not ironclad … I told you so 🤷‍♂️. Some of my fellow white boys have this distorted idea of the law where you think you can just accost and antagonize black people with the N-word, and if they swing on you, then you’re justified to shoot them 🙄. That’s not how the law works.

@talmud1c @IanCarrollShow Was just thinking this recently, Nick is a worthwhile adversary. Most of these other spambots and conspiratards are simply a joke.

@IanCarrollShow As a Jew, I can say honestly: Nick is a way better adversary than you. He's at least smart and funny. You're just a low IQ slop merchant and you're not funny.

This is how a snake tells you to stop talking about Epstein and all the other important anti Israel topics we mustn’t stop talking about. He just dresses it up in word salad to make it sound clever. It’s not.

@RNAiAnalyst LOL Is he just not gonna address at all what happened while he was at FDA?

Glad #Prasad is back to the podcast circuit. Starts off with claiming that everything that is to come is well researched and based on facts... ...but ends talking about his gut feelings + how they are superior to what actual experts in the field have found through research. youtube.com/watch?v=cvGaSg…

@michaelzlin Uh, no. Where is your basis for suggesting that it has anything to do with the country of origin? There is no longer a covid pandemic. That's the reason it is not approved sooner.

Ensitrelvir succeeded where Paxlovid had failed to show efficacy, in post exposure prophylaxis. It’s also been known for years that it prevents severe late disease in those already symptomatic as well as Paxlovid. Ensitrelvir should have been approved long ago. If it were from an American rather than Japanese pharma, it would have been.

Suddenly it starts to make sense

@LevineJonathan @IraStoll @NickKristof jfc

Also from @IraStoll @NickKristof father also wrote a letter to the editor of the Times in 1989 defending Paul Touvier, the intelligence chief of a pro-Nazi militia in Vichy France who was convicted of killing seven Jewish hostages. You can read that here: nytimes.com/1989/07/19/opi…

NEW from @IraStoll @NickKristof father fought for the Nazis during WWII — something he admitted in his 2024 memoir, Chasing Hope "When I was growing up and other kids talked about their dads heroically battling the Nazis, I kept quiet. I didn't want to admit that my father had actually fought for a year on the same side of the Nazis." freebeacon.com/media/times-co…

@exALEXANDRIA "Yeah man, so many facts we got from Nick Fuentes, like the Jews are so bad and do so many financial crimes, and that's why we're supporting James Fishback and Dan Bilzerian!" Literally financial scammers.

James Fishback is everything that is wrong with the GOP He just sucks

🚨 SURMOUNT-MAINTAIN published in Lancet today 💉 Individuals after 60 weeks of high dose tirzepatide randomized to maintaining high dose vs. reduce dose to 5mg vs. placebo and followed for a 52 week maintenance period. 📊 After the 52 week maintenance period: ⬇️ High dose tirzepatide: 21.9% weight loss ⬇️ 5mg tirzepatide: 16.6% weight loss ⬇️ Placebo: 9.9% weight loss 🔑 Long-term treatment is necessary to maintain bodyweight reduction and its associated cardiometabolic benefits. Lowering the dose leads to variable degrees of weight regain. Discontinuation more definitely leads to weight regain. thelancet.com/journals/lance…

@EYakoby Let these people go to their Allah. Why is it so troubling for hasbarists and liberals to help these gazans achieve their ultimate goal?

Palestinian in Gaza: “We are the ones who launched this war, and we will be the ones to end it. Until the last drop of our blood, we keep offering, and sacrificing until all of us die, for the sake of Allah." They never learn.

Bibi said Israel will sue the New York Times for its blatantly libelous and disgusting article about Israeli dogs raping Arab children. I hope he goes through with this. These bastards need to start paying for making up monstrous lies that get innocent people murdered.

@RudyResearch What is an "emerging obesity asset" exactly?

$Abbv asking for emerging obesity assets guys not your $vktx shitco

'On Jewish soldiers, he's a bully. Toward Palestinians - a diplomatic softie. A contemptible man who is not part of the people of Israel. How can you win with a Chief of Staff like that? It's simply impossible.' We warned about Zamir And here we are youtu.be/Y4EY1nYGY_M?si…

@RexStructorum @johnnymaga When you hire a guy who "doesn't do email" things like this will happen

@johnnymaga If that’s how they resign, why shouldn’t he? She could have written a formal resignation letter instead of a text.

I love how Trump will just post screenshots like this — a high level administration official’s resignation. We’ve never seen this before in the history of the presidency.

@jeffcafe_ @Biomaven @VerbinnenAndrew Edema is generally not good.

@Biomaven @BiotechObserver @VerbinnenAndrew Fair enough. Just mostly pushing back on the safety side, there been a lot of fearmongering by dumb YouTubers over the years.

We disrupted a $4 billion company with an AI chatbot and a thousand dollars. Here's how we did it. Veradermics ($MANE) raised $256M and trades at a ~$3.8B market cap on the premise of extended-release oral minoxidil. The idea makes sense. Oral minoxidil works, but standard oral minoxidil releases fast. You take the pill, the drug spikes quickly, and that spike is where a lot of the side effect concern comes from (heart rate, blood pressure, fluid retention, etc.). So the question is whether you can give patients more minoxidil but release it more slowly, getting stronger hair growth without the same side effect burden. That is what Veradermics is trying to prove with VDPHL01. The data so far is genuinely impressive. In Study 302, Veradermics tested 8.5mg once daily and 8.5mg twice daily in men with pattern hair loss. After 6 months: placebo gained +7.3 non-vellus hairs/cm², 8.5mg once daily gained +30.3, and 8.5mg twice daily gained +33.0. They also reported no treatment-related serious adverse events, no cardiac adverse events of special interest, and overall side effect rates similar to placebo. For context, finasteride 1mg has been reported around +12 to +16 hairs/cm² versus placebo. So yes, VDPHL01 looks very real. But here's what struck us. Minoxidil itself is not a new molecule. It is a well-understood drug, used for decades. Low-dose oral minoxidil is already commonly prescribed off-label for hair loss today. Veradermics is taking the traditional biotech route: large trials, FDA approval, patents, years of development, and eventually what will likely be premium drug pricing. That model can make sense, but we started asking a different question: if the active ingredient is already familiar, could we build a practical extended-release oral minoxidil option for patients sooner? Not Veradermics' drug. Not their gel matrix. Not their clinical dataset. But the same basic concept. So we started digging. We used ChatGPT over a couple of days to review the existing formulation literature and patent landscape, and landed on a different approach: a lipid matrix. Lipid matrices are commonly used in drug formulation to slow the release of active ingredients, but to our knowledge nobody had applied this approach to oral minoxidil for hair loss. We put together the formulation instructions and sent them to our compounding pharmacy. Our pharmacist made the tablets and shipped them back. Then we ran dissolution testing to see how they released compared to standard immediate-release oral minoxidil. The product we tested was MINX: a 5mg once-daily oral minoxidil tablet designed to release more gradually than a standard immediate-release tablet. The data surprised us. Standard oral minoxidil released almost the full dose in under 10 minutes. MINX released gradually over approximately 12 to 14 hours. We tested it in two environments. pH 1.2, which mimics the stomach, and pH 6.8, which mimics the small intestine. We got the same gradual release curve in both. Same drug, totally different release profile. To be very clear: this is dissolution data in beakers. It is not human clinical data. It does not prove better hair growth. It does not prove fewer side effects. And MINX has not gone through anything resembling Veradermics' clinical program. That is exactly why we are starting at 5mg, not 8.5mg twice daily. If the tablet ever released faster than intended, 5mg is still within the range already commonly used off-label for hair loss. The goal is not to overstate what we have. It's to build useful, patient-centered products faster. MINX exists because we think the drug development landscape is changing. A small team with scientific curiosity, AI tools, compounding and telehealth infrastructure, and fast lab validation can now move in weeks on ideas that used to take years just to begin testing. Veradermics deserves credit for pushing extended-release oral minoxidil into the mainstream. But patients should not have to wait years and pay premium pricing to access every practical improvement around a drug that clinicians already understand. MINX launches May 11th on Anagen. If you made it this far, drop a comment and I'll DM you the waitlist link.

@hartmann27468 @asukagrypr Both views are retarded. At least Dan's is honest and not trying to fool people by hiding and sugarcoating the Jew hatred so people unwittingly accept the JQ agenda. That is far more evil.

@asukagrypr > Dan Bilzerian is a low IQ antisemite and hurting the JQ movement with his blatant jew hatred. > Dan Khazarian is as least 12,5% jewish, therefore he qualifies as a jew who is not to be trusted and cannot possibly speak for non-jews. Which one is the low IQ (antisemitism) take?

Bro that is for 87.5% German 12.5% j-wish not Armenian and j-wish 🤣🤣