R. Bryan Rumble

@Matt_Pinner Well hello there High Protein Peanut Butter Chocolate Flavour Bar.

You have to name him the last thing you ate

@elbouzzz @Faheem_uh Right? But how do they know they're reviewer 2?

@Faheem_uh It’s always reviewer 2

When you submit your paper to a journal This is how reviewer 1 and reviewer 2 treat it

@SuperSisi Snatcher

What's the first game you're playing?

@exQUIZitely I can beat this game without sliding. No I can't.

What was your first impression when you played Descent by Parallax Software? Descent (1995) was an incredible game for its time, introducing a world-first feature: six degrees of freedom. No other game before allowed such complete movement control, though it came at a cost - at least for me - inducing vertigo if you were prone to it. I'm only half-joking but playing Descent those first couple of times was both amazing and genuinely nauseating. Flying through mineshafts, turning left/right, up/down, and doing full 360-degree rolls was all part of the charm, but the side effects were very real. People often talk about Duke Nukem 3D, Doom, Quake, Half-Life, and Unreal when discussing 90s shooters, yet one game that introduced a truly novel concept is often overlooked among the classics. Remember, this was 1995 - nothing like it had been done before - and it came from an unknown developer (Parallax Software's first game), which makes it even more impressive.

@YoDanno B|X for me

For some, this was their introduction to the world of fantasy. what was yours? 🖼️Jeff Easley - cover art for the 1983 revised edition of the Advanced Dungeons & Dragons Player's Handbook. I

@ASCO has released the first-ever Living Guideline for Systemic Therapy in Metastatic Castration-Resistant Prostate Cancer (#mCRPC). Version 2026.1 is now live, providing real-time updates to the May 2025 full update. Stay current: ascopubs.org/doi/pdf/10.120…

@FATAL1TY Killzone, Watch Dogs

Unreal Tournament for starters.

@Matt_Pinner Devs

Name one

@simonmaechling Hola

I’m not a bot. I’m a chemist. I’m a human with a PhD trying to talk about science. My goal is simple, make people smarter, not angrier. Science, explained clearly. If you’re human too, drop a “Hi” so I know I’m not shouting into the botnet.

@stfuesh Stoned ostrich

@Matt_Pinner Devs

What is the best?

@lxcsxsn @OxfordFrom Lots of people do research without a PhD. I'm well published with an MSc. Many physicians doing research are doing so with an undergrad MD.

@OxfordFrom And how can you do research without a PhD???

PSA: if you contact me about doing research under my guidance, do some research without my guidance first. For example, on the topic of what kind of research I could possibly provide guidance for.

@YoDanno Happy birthday!

I get by with a little help from my friends… Thank you all for the most wonderful birthday wishes. This little corner of X is a nice place to hang out thanks to you. Larry Elmore - The Companions of Dragonlance

@ASCO Guideline Clinical Insights: Systemic therapy in mCRPC, released Sept 4, 2025. Thanks to @rohangarjeMD, Dr. Rahul Parikh, @IrbazRiaz, and Dr. Arsalan Naqvi for their leadership on this article.

The Updated ASCO Guidelines on Metastatic Castration-Resistant Prostate Cancer - @RohanGarjeMD @BryanRumble @ASCO oncodaily.com/url/289209 #Cancer #OncoDaily #Oncology #GlobalAwareness #FightAgainstCancer #CancerWorld #ASCO #mCRPC

@memeslich PF and OSE (so, B|X)

What edition of Dungeons & Dragons is your group playing?

@OriginalGrogna1 @GigaBasedDad Pretty much true

@GigaBasedDad lol! Looking at you @BryanRumble !

@therealcliffyb Gears of War. Fan of them all, but GoW was one serious flex.

What's your favorite game of mine that I've worked on?!

@Matt_Pinner These were peak boomer tech. Before computers and consoles, this was how boomer dads flexed.

You may be old but, are you this old??

@The_DrunkDragon Gen I, cause I'm an older Gen X