Cameron A. Schmidt, PhD

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Cameron A. Schmidt, PhD

Cameron A. Schmidt, PhD

@CAS_ReproLab

Complex Adaptive Systems Lab @ECU_Biology | We Study the Multiscale Biology of Searching and Finding | https://t.co/xrmzvYlgQc

In the Lab; Greenville, NC Katılım May 2012
2.2K Takip Edilen1.4K Takipçiler

2026 Yıllık Özeti

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Cameron A. Schmidt, PhD
Cameron A. Schmidt, PhD@CAS_ReproLab·
Some recent collab work exploring how phase transitions in movement persistence can lead to a statistical gain in sperm search efficiency🔥 #ReproRocks #ComplexSystems #ActiveMatter mdpi.com/1099-4300/27/5…
Cameron A. Schmidt, PhD@CAS_ReproLab

Now out in @PLOSCompBiol 🎉 We used multiagent models to explore how search for an egg emerges as a statistical property of sperm variation and used Bayes theorem to quantify selection. A single sperm wanders.. Many sperm compute🔥 #ReproRocks #Complexity youtube.com/shorts/H7RXWfA…

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Hattie Chung
Hattie Chung@hattaca·
How does aging reshape a tissue that must continually rebuild itself hundreds of times? Using spatial transcriptomics, we find that ovarian aging disrupts the coordination of cells across space and time before reproductive cycles stop. #OvarianAging
Nature Aging@NatureAging

🗞️Our June issue is live!✨Read about the healthspan and lifespan effects of time-restricted feeding in mice, insights from mathematical models of aging, how R-loops drive the SASP, & much more nature.com/nataging/volum…

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SSR
SSR@SSRepro·
"I ended up with the project that nobody wanted to do." 🧪 Dr. David Pepin discusses how a "failed" postdoc led him to MGH and a technical challenge that paved the way for his Roger V. Short Medal-winning research. A must-watch for trainees!
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Cameron A. Schmidt, PhD
Cameron A. Schmidt, PhD@CAS_ReproLab·
My computer is writing and testing fully functional, modular, and intuitive software while I make breakfast for my kid.
GIF
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SSR
SSR@SSRepro·
🚀 Early-Career Researchers! The SSR Emerging Investigator Grant is open! Get seed funding for preliminary data in reproduction & fertility. 🧬 🌍 Global applicants welcome 📅 Deadline: May 29, 2026 🔗 Apply: ssr.org/funding-and-gr… Follow all guidelines to qualify!
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Complexity Cat 🐱
Complexity Cat 🐱@amahury0·
If people want the deeper background behind my critique of pancomputationalism, here are 10 books that shaped my thinking. None is "the answer" by itself, but each helped me break the spell of the machine metaphor in biology. Many of them are available online, DM if not!/1 😉
Robert Ziman@robziman

@amahury0 CCat: what are the best books and resources, in your opinion, for getting started with the technical details on this and all the related subjects you write about?

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PRX Life
PRX Life@PRX_Life·
Employing a minimal but biochemically relevant model of trigger waves, researchers obtained an analytic expression for wave ignition thresholds in #CellSignaling in 1D and numerical solutions in 2D and 3D. Check out the study: go.aps.org/4bULRj1
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Cameron A. Schmidt, PhD
Cameron A. Schmidt, PhD@CAS_ReproLab·
@amahury0 We're pretty steeped in digital computing. Is the emphasis on symbolic representation influenced by that? Do other representations fit in? Analog for instance? Is the goal to answer: What is the 'right' set of characteristics imputed from technology to describe biology?
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Complexity Cat 🐱
Complexity Cat 🐱@amahury0·
So, for the umpteenth time, pancomputationalism is not a suitable way to describe life. I'll soon be writing a full essay in which I explain each of the points discussed in this thread in detail, but for now I've provided enough references for skeptics to consult. Stay tuned!/12
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Complexity Cat 🐱
Complexity Cat 🐱@amahury0·
No, the computational theory of finite-state automata isn't all it takes to do everything that any living system is capable of doing. Geez! Here's a list of solid reasons and hard facts that the mainstream proponents of pancomputationalism don't want you to know.../1 🤫
wildiris@wildiris19

No, I meant Turing complete. I’m completely frustrated with constant references to “Turing completeness.” You are correct, no finite system can be Turing complete. Which means it’s a completely useless metric when approaching any finite computational system; whether biological or digital. I only wish people would just stop using the word and move on. Every computational system that can be physically built will be nothing more than finite state machines, random-access memory elements, and sufficient combinational logic to glue it all together. The computational theory of finite state automata is all you need to do everything that any living system can do. Sigh!

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Kelsey Fisher-Wellman, PhD
Kelsey Fisher-Wellman, PhD@KFW_Lab·
New publication from our group. We examine the primary functional consequences of mtDNA mutations across major organ systems. Spoiler: the cumulative mutational burden broadly phenocopies a complex I deficiency. cell.com/iscience/fullt…
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Tsuyoshi Hirashima
Tsuyoshi Hirashima@hirashima0203·
Using intravital imaging in mice + drug-inducible contraction, we found the vas deferens operates as a flow-regulated valve system. Luminal sperm flow is not just an output, but it feeds back to open the lumen (valve), remodel tissue geometry, and stabilize the sperm transport.
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Tsuyoshi Hirashima
Tsuyoshi Hirashima@hirashima0203·
Let me announce the other preprint uploaded last week: “Flow-driven lumen remodeling and valve opening in the vas deferens” biorxiv.org/content/10.648… This work tackles a fundamental question: how does a reproductive duct dynamically control its lumen shape during sperm transport?
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SSR
SSR@SSRepro·
How do vaginal bacteria impact sperm function? 🔬🧫 Don't miss Session #4 of the Trainee Journal Club! Speaker Sarah Dohadwala (@BU_Tweets) breaks down the remodeling of the sperm glycocalyx. Moderated by Leah Simon, PhD (@CUAnschutz). Register today: f.mtr.cool/ifzpeebyyd
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