Constance Bailey

@JohnGoldman What if you are a single parent, or someone whose spouse travels for work or has shifts. Who is watching the kids while you run at 5:00 am?

Training for a marathon the right way does take a lot of time. And i am married with three kids and run a business. It’s not easy. There’s sacrifice. Lots of dark mornings alone. Running 13 miles before breakfast on Mother’s Day. I bet you could make time. I do. You just don’t.

@Peter96355998 @clairlemon Maybe we need adult XC teams

@clairlemon Too individualistic for it to be a sign of progress. If you can't be bothered going to Parkrun this Saturday no one is going to hold you accountable. Teams sports are not like that. Bowling alone.

Running culture is an underrated sign of progress, imo. More people have tracking devices & are discovery the benefits of regular training on things like sleep, mental health, & general wellbeing x.com/TimAdams76/sta…

@mid_hank @Brady_H TBH perhaps that's why 70-80 mile weeks and occasional 30 minute doubles seemed manageable to me with a demanding job in my 30s...there's sort of a limit to how much you can train running due to the impact.

@mid_hank @Brady_H I used to do 20 hours of training a week swimming when I was in high school. I don't think it was great for a lot of us. I personally had a lot of burnout with it, and I didn't get my period until I was nearly 16.

Having your 11-year-old child run a hard half marathon (and train for one) is ludicrous. IMHO.

@mid_hank @Brady_H 1. Swimming lacks impact 2. So many menstrual issues were swept under the rug and the consequences are not as obvious without the risk of stress fx that running has. But RED-S has consequences even if you aren't breaking bones.

@mid_hank @Brady_H I've thought about this a lot as someone who was a swimmer growing up who started distance running as an adult

@stuartlandsberg @janecoaston Zone 4 is supposed to be ~ one hour race pace? Maybe he was in zone 4 towards the end, but doubtful he could be for a 2 hour race.

@janecoaston Not necessarily. A lot of elites push into zone 4 for a marathon. They just have an incredible ability to maintain a stupidly high level of effort.

what gets me is that this means he can stay in zone 3 while running at that pace. like, he can keep a heart rate of 155-160 while running 4:30 repeats for two hours.

@stevemagness Korir runs at 7,000 feet altitude on hilly dirt roads with variable footing and puts in 130 miles per week often running twice a day. I doubt he runs all his easy runs at 9:00 pace, but that context is important.

On running slow: You run slow enough to recover from the rest of the training and to accumulate volume. The more miles you run and heavier training load there is...the more you have to compensate somewhere. It acts as a kind of safety mechanism. When you're running 100+ miles per week, your body makes it where you can't go out the door at 6 minute miles after a long run or hard workout. So you listen to your body and ease into it. If you're running way fewer miles, you can handle running a bit faster and still bouncing back and recovering. The danger though for lower mileage runners, especially amateurs is...just because you can get away with it, doesn't mean you can do it. If you run 25-30mpw and because of the low mileage can hammer all day, it's sometimes what prevents you from being able to increase the load. Sure, you can handle going fastish on every 4 mile run, but when you try to bump up the mileage, you often fail because it's hard to extend that 4 miles fastish to 5, 6, 7, etc. It's why even off quite moderate mileage, amateur runners need to run much slower. They have a lower capacity to handle the load AND no built-in governor or ability to listen to their body to naturally slow down like the elites have. So sure when we see John Korir run 9min pace, we need the context that he's running 130 miles per week. And that doesn't mean every amateur runnign 30mpw should run comparatively slow. But at the same time, we still have a lot of amateurs who end up running way too fast at 30mpw, which prevents them from handling the one thing that would help them breakthrough, gently bumping up the volume for a sustained period of time.

@stevemagness @Alan_Couzens Maybe if I had been sharper, I could have run ~19:00 at the time, but putting in a lot of miles always made me much faster. And even if my goal race didn't pan out, my workouts got faster as I got stronger.

@stevemagness @Alan_Couzens When I ran that, I did zero 5K specific training, I was just doing base miles (~50ish mpw) plus a few fartleks and tempos coming back from my marathon break getting ready to start a new block.

I dunno, man... If you're say a 20 minute 5K runner doing 30mi/wk w/ 2 specific interval workouts/wk. You drop the interval workouts for a year and commit to building to consistent 60mi/wk of *only* easy miles plus strides. Then run a 5K. I know where I'm putting my money.

@nanransohoff Curious why biopsy/sequencing the polar body from meiosis 1 for aneuploidy couldn't be a thing.

I’m a big advocate of egg freezing (and have done several rounds myself). If/as this becomes more common, I think there would be huge value (and likely a huge business) in being able to determine if an egg is ‘good’ or not. We know at least some things embryo quality because we can grab a few cells from a 5-day blastocyst, usually without damaging it. But we seem to know basically ~nothing about the quality of a mature egg. As a result, it’s very hard for a young woman to know if she’s actually frozen enough. So, today, the main thing she can do is stockpile more – which is both expensive and unpleasant. Obviously we cannot use the same sampling technique as with an embryo because an egg is a single cell. But it seems like there could be other ways of knowing more (possibly through imaging, through sampling and sequencing spent media, etc.). I know lots of women who would pay $$ for this as an add-on to an egg retrieval. Is anyone seriously working on this? cc @seemaychou and @RuxandraTeslo who are also interested in this topic

Establishing Conserved Biosynthetic Gene Clusters of the Phylum Myxococcota biorxiv.org/content/10.110…

@CartoonsHateHer @smokedgouda5 Why do we feel the knee jerk impulse to clarify "unrelated to age" as if using IVF for age (which it's not even that effective for compared to other reasons) is shameful?

@smokedgouda5 When we met we both wanted 2. Briefly we flirted with 1, when it was time to do IVF (unrelated to age) we were split between 2-3. Now he wants 2 and I want 4 lmao

For better or worse, birth rate discussions are framed as women choosing to have fewer children. But for most married couples, it’s a joint discussion. Why are we assuming men don’t have opinions on this? Link in replies.

My dept in London at Imperial (Bioengineering) is recruiting a group leader at Professor level 🧑‍🎓 Please RT. It's a great department with world-class expertise in all sorts of biomedical & biological engineering topics, including synthetic biology. 🇬🇧imperial.ac.uk/jobs/search-jo…

@igordownunder Track record matters (publishing frequently and/or in top journals and having highly cited papers) and first/last authored papers, just not so much the actual numbers.

@igordownunder Hmm not my experience applying for grants in NIH, NSF, DOE, and various DOD agencies along with some fancy philanthropic awards. Some institutions and universities care for promotion and internal stuff.

Citation metrics: In the US I found they were not at all emphasized when applying for grants. I would look up my H-index/total cites once a year when filling out some annual paperwork for the university. In Australia I find them extremely emphasized in grant applications.

It just wasn't as focused on metrics

To be clear, there were often sections when I would make an argument about my track record/contributions to science/relevant pubs, highlight 1st or last authored papers esp. w/ PhD students and postdocs, demonstrate I had published high impact papers or highly cited papers, etc.