CSHLPress

Can we map miRNAs and their targets in brain tissue? Current spatial transcriptomics methods can't simultaneously measure miRNAs and their target 3′UTRs. This #RNASpecialIssue review explores the challenge and emerging solutions: bit.ly/4sv5Dq1 #RNABiology #MicroRNA

RNA function is defined by its interactions. This review from the #RNASpecialIssue highlights new CLIP-based methods to map protein–RNA and RNA–RNA contacts, advancing reconstruction of RNA interaction networks at transcriptome scale. bit.ly/41KDfWl

How well can machine learning predict RNA secondary structure? This review in the #RNASpecialIssue examines current approaches—from deep learning to hybrid models—while exploring the field’s “generalization crisis” and the rise of RNA foundation models. bit.ly/4spSj6s

How well do deep learning models generalize in RNA secondary structure prediction? This Perspective from the #RNASpecialIssue explores the “generalization gap” limiting current methods and how AI is reshaping RNA structure prediction. bit.ly/4dx1lec #Bioinformatics

Nanopore direct RNA sequencing is reshaping epitranscriptomics — enabling direct detection of RNA modifications and RNA damage across entire transcriptomes with long-read sequencing. New review from the #RNASpecialIssue: bit.ly/3POaGo9 #RNA #Epitranscriptomics #Nanopore

Renowned Scientist Nancy S. Wexler Shares Extraordinary Personal and Scientific Journey in New Memoir, My Life, My Science: Pursuing a Cure for Huntington’s Disease globenewswire.com/news-release/2… @hdfcures @CSHL #HuntingtonsDisease

🚨 NEW ISSUE ALERT!!! 🚨 New Research articles online now at Genes & Development! Also in this issue, an Outlook on target-directed miRNA degradation, and a Review discussing the recent advances in optogenetics! Click here to learn more: ➡️ genesdev.cshlp.org/content/40/9-1…

What’s next for RNA biology at system scale? In this #RNASpecialIssue editorial, the editors frame a shift toward quantitative, integrative approaches, highlighting advances in measuring, modeling, and ultimately manipulating RNA across biological systems. bit.ly/41hv9UJ

We're pleased to feature a recent Special Issue of RNA showcasing advances in system-level RNA biology—from epitranscriptomics and RNA damage to deep learning–driven structure prediction and beyond. A strong snapshot of where the field is heading. bit.ly/RNAspecialissu…

The new issue of @genomeresearch is now live. Follow the link to new research on somatic mutant alleles in bulk tumor samples, honey bee gut microbiota, and more! tinyurl.com/Genome-Res-36-4

The new issue of @genomeresearch is now live. Follow the link to new research on chromosome engineering in 8p syndrome, convergent evolution in arid rodents, and more! tinyurl.com/Genome-Res-36-3

Genetically vulnerable to Huntington’s Disease, Nancy Wexler devoted her life to ground-breaking work that revealed the HD mutation and produced a test for susceptibility. Now living with HD, Nancy Wexler has a powerful autobiography published by CSHL Press: "My Life, My Science: Pursuing a Cure for Huntington’s Disease". Pre-order from Amazon at amz.cx/3c1w

The new issue of @genomeresearch is now live. Follow the link to new research on transposable elements in pancreatic cancer, genomic evolution in living fossils, and more! tinyurl.com/Genome-Res-36-2

The new issue of @genomeresearch is now live. Follow the link to new research the 3D genome organization in breast cancer, assisted reproductive technology mutation rate, and more! tinyurl.com/Genome-Res-36-1

The new issue of @genomeresearch is now live. Follow the link to new research on wheat centromere adaptation, Quadrupia - a G-quadruplex database, and more! tinyurl.com/Genome-Res-35-…

Now Available! “Epigenetics: History, Molecules, and Diseases” cuts through hype to trace the field from its origins to today’s genomic landscape. A clear, authoritative guide to what epigenetics is—and is not. Now in print + eBook formats: bit.ly/epigeneticsbook

Coming Soon: 'Epigenetics: History, Molecules, and Diseases' by John Greally. A clear-eyed, provocative journey through one of biology’s most captivating and misunderstood ideas. Available in print, eBook, and Kindle formats Tuesday, October 21.

The new issue of @genomeresearch is now live. Follow the link to new research on microglia in neurodegenerative diseases, intron retention in nuclear RNA complexes, and more! tinyurl.com/Genome-Res-35-…

🚨 NEW ISSUE ALERT!!! 🚨 New Outlook, Review and Research Papers online now at Genes & Development. Click on the link to learn more: ➡️ genesdev.cshlp.org/content/39/19-…

The new issue of @genomeresearch is now live. Follow the link to new research on HER2 isoform diversity and drug resistance in breast cancer, off-target site detection in prime editing, and more! tinyurl.com/Genome-Res-35-9