Jon Fay

Excited to share our latest work! My lab in collaboration with Dr. Jacobson's lab has decoded how the P2Y14 receptor binds uracil and glucose. This purinergic GPCR continues to reveal its secrets. ❄️🔬nature.com/articles/s4200…

In collaboration with Dr. Farrens and Yao. Ever wonder how you see green, even when the sun be blastin? We’ve been digging deep into the greenest receptor around. 👀 Excited to share our latest publication: pnas.org/doi/10.1073/pn…

I am excited to share our latest work in @Neuron exploring the pharmacology of psychedelics. I am deeply grateful to my PI, Prof. Bryan Roth, @zenbrainest, for his exceptional guidance, and to all my co-authors for their valuable collaborations.

It's finally out! Our "somewhat" thorough study on psychedelic polypharmacology. Congrats to @jainmk6 @zenbrainest and everyone else involved! sciencedirect.com/science/articl… #psychedelics

Happy to share that this work on the structural biology of #psychedelics is finally out! Big shout out to all involved, especially @zenbrainest for all of the support! The structural diversity of psychedelic drug actions revealed | Nature Communications nature.com/articles/s4146…

Glad to share a great teamwork with @sushmajumdarlab @sevakat1, Jay McLaughlin lab, and @AmynahPradhan @Cannabatopia. This bitopic approach pioneered by Drs. Majumdar and Katritch works pretty well in GPCRs. Thanks to the support from @NIDAnews and WashU nature.com/articles/s4146…

Yuuge paper on #psychedelics The structural diversity of psychedelic drug actions revealed nature.com/articles/s4146…

Happy to share a pre-print of some recent work. This is our first time using bioRxiv. I suspect we will be using it more moving forward.

@vikasnavaratna Very beautiful mugs

As a thanks for all the snacks that I bring, a grad student from our neighboring lab handcrafted a pair of clay coffee mugs for me.

Lessons from a Toad Psychedelic about the Role of different Serotonin Receptors in Psychedelic Physiology: nature.com/articles/s4158… Congrats to Audrey and @LankriDavidIL in this collab with @SamesLab and @ScottRusso published in @Nature

Why do phosphate-containing medications cause itch? MRGPRX4! Latest @RothLabUNC @Cannabatopia and Dong Lab (HHMI/Hopkins) collaboration: doi.org/10.1126/scitra…

@IevaDrulyte @thermofisher Nice to meet non virtually.

Are you attending the 4th Alpine Winter Conference on Medicinal and Synthetic Chemistry next week? If so, visit @thermofisher booth #11 to learn about the latest advancements in #cryoEM technology and how it can accelerate drug discovery! bit.ly/3vJe0Xw

Excited to have published our collaborative research on the secretory trafficking of the SARS-CoV-2 spike! #SARSCoV2 #spike #NMR @NIGMS @NatureComms @UMmedschool @UMBaltimore @UMD_IBBR @UMDCBMG @ChemBiochemUMD @LoyolaMiim @debajtdey @pierce_lab nature.com/articles/s4146…

@F4ustus Same map different number

#CryoEM #Memes

@allostericstate There is literally a button for this now and has been commands for this for years. Map quality be the almost the same tho... at ~10% duplicates - so can fix fairly easily by editing the entry.

@breakliquid I like to crank the lid down to cause tube deformations

New PCR machine, how to prevent this?

@JoshuaStrauss5 The post it wall is behind Jason

It's that time of year again for my favorite holiday. “CryoWEEN 3.14” Jason is working on a grant no one is safe.

@vikasnavaratna Cross cross apple sauce

How it started... how it's going.

exciting!

This was a sad day in the lab, however these columns can be fixed! Cytiva will tell you otherwise but here is how you do it.