Cardoso Lab

🚨 New paper from our lab @CardosoLab We review how voltage-gated ion channels drive neuronal dysfunction in motor neuron disease—and why targeting channel gating may unlock new therapeutic strategies. A must-read for neurodegeneration & ion channel biology 👇 pubmed.ncbi.nlm.nih.gov/41765206/ #ALS #MND #IonChannels #Neuroscience #DrugDiscovery

🕷️The @CardosoLab recently published two intersting studies on spider-venom peptides targeting Nav channels, Open Access @Toxins_MDPI and Biochemical Pharmacology. Our findings support the hypothesis that Nav-targeting pharmacophores represent an evolutionarily ancient molecular feature of spider venoms @IMBatUQ @UQ_News PMID: 41295876 PMID: 41319925

RT @DrFeCardoso: Our team's latest research featured @TrendsinPharma discusses cutting-edge advancements driving venom peptide-based drug d…

High throughput cellular assays of voltage-gated calcium and sodium channel youtu.be/0zOuAojXiik?si… via @YouTube

Calling all Venom Research Fellows! Don’t miss this exciting meeting in Brasília, December 11–14, 2024. It’s a fantastic opportunity to connect and share insights on venom-derived drugs. I hope to see you there! 👩🏻‍🔬🐍🕷️🦂🐝🔬💊

I am pleased to share this fantastic collaborative effort by @CardosoLab @CNZdenek @insect_venomics investigating venom evolution in Reduvvidae smarting out neofunctionalization of toxins from cytolytic and pain-inducing to pain-free anticoagulant activity. @IMBatUQ @CellPressNews Venom exaptation and adaptation during the trophic switch to blood-feeding by kissing bugs: iScience cell.com/iscience/fullt…

Our lab's latest research is out in ToxiconX. We've pioneered a cutting-edge High-content fluorescence bioassay that accurately discerns between pore formation, ion channel modulation, and cell membrane lysis induced by venom components. 👉bit.ly/4agoUmF 🐍🕷️ @CardosoLab @IMBatUQ

🕷️🐍 Had a fantastic time catching up with fellow toxinologists at the IST World Congress in Singapore! 👏 Congrats to @CardosoLab postdoc Jessica for winning the award for best ECR talk! @IMBatUQ @ToxinTalks @PeigneurSteve @LuddeckeTim @MatyasBittenb @anaturalist @anemonegoddess @SpecSpiderVenom @evolriffs

Could venoms one day be used to treat neurodegeneration? In a recent interview, we asked @DrFeCardoso about @CardosoLab's latest research, their involvement in #MotorNeuronDiseases, and the future of this work. Read the interview here: lnkd.in/dquPgwe3

I'm thrilled that @NanionTech has spotlighted my research on venom-based drug discovery in this podcast. This fuels my passion for innovation and the groundbreaking potential of venom in modern medicine @CardosoLab @IMBatUQ 🕷️🐍🧠 podcasts.apple.com/au/podcast/spo…

🎉Our lab is immensely proud of postdoc Jessica for winning the award for best ECR talk at the IST World Congress in Singapore! Special thanks to @sophionbio for providing travel support 👏🕷️🔬🧠💊 @DrFeCardoso @IMBatUQ

To mark #InternationalWomensDay , the #NatureReviews Collection on women's health has been updated. Click here to read articles on various aspects of women's health, including a hot-off-the-press Review on heart failure therapies from @NatRevCardiol: go.nature.com/30kDWG3

You can read our latest issue here: cell.com/molecular-cell…

By wirelessly recording signals from deep-brain stimulators in patients with Parkinson's disease in an outpatient setting, Soh et al. show that the STN – known for its role in motor control – also exerts control over non-motoric, attentional processes. tinyurl.com/mvuwy785

AlphaFold2 and RoseTTAFold are limited to predicting the 3D structure of proteins. A new all-atom method models complete biomolecular assemblies, including proteins, nucleic acids, small molecules, metals, and covalent modifications. #NBThighlight science.org/doi/10.1126/sc…

Will we witness an AlphaFold moment for functional protein engineering and design? Will we solve the protein design problem — that is, the ability to create tailor-made functional proteins on demand — once and for all? go.nature.com/4bLthb0 rdcu.be/dy2d5

New online! Schizophrenia: from neurochemistry to circuits, symptoms and treatments go.nature.com/3tr6DDl