
Chang Jiang 姜畅
305 posts

Chang Jiang 姜畅
@ChangJiangLab
Assistant member @MoffittNews studying redox biology, cancer metabolism and mitochondria.










(1/n) Excited to share our new preprint! We uncover that RNA actively promotes nucleation and function of pathogenic condensates, amplifying locus-specific oncogenic transcription and promoting tumorigenesis. #epigenetics #condensates #cancer #RNA biorxiv.org/content/10.110…






New! Online now: Iron-addicted colorectal cancers exploit heme-complex II axis to resist oxidative cell death dlvr.it/TSlWK5





Our new work by @shanshanliu1218 and @gadmark addresses a fundamental question: how does ER maintain its unique oxidizing environment, while rest of the cell is reducing? Here, we identify SLC33A1 as the major ER GSSG exporter in mammalian cells. nature.com/articles/s4155…


Thrilled to share our new paper: SLC33A1 is the long-sought ER GSSG exporter, maintaining redox homeostasis in the ER. Huge congratulations to my co-first author @shanshanliu1218 and my PIs @KivancBirsoy and @HiteLabMSKCC for leading this work. nature.com/articles/s4155… 🧵 1/9
