Denise Young

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Denise Young

Denise Young

@DDYoung01

Pediatric GI @UHRainbowBabies with a focus on IBD and quality improvement. Tweets are my own.

Cleveland, OH Katılım Ekim 2018
234 Takip Edilen131 Takipçiler
Denise Young retweetledi
The Lancet
The Lancet@TheLancet·
The American College of Obstetricians and Gynecologists has made the decision to forego federal funding in order to maintain the integrity of their evidence-based work on maternal health, preventive care, and more. Find out more in a new letter: hubs.li/Q03-bHZh0
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Tauseef Ali MD, FACG AGAF FACP
The FDA has approved TREMFYA® (guselkumab) for fully subcutaneous induction in adults with ulcerative colitis — making it the first and only IL-23 inhibitor with a complete SC regimen. 💉✅ 🔹 Why this matters: 🌸 Convenience: No IV required — patients can start therapy at home. 🌸 Flexibility: Choice of SC or IV induction supports shared decision-making. 🌸 Access & Capacity: Less strain on infusion centers, more independence for patients. 🌸 Consistency: Strong clinical outcomes with early symptom improvement as soon as week 2 and sustained through week 24. This milestone expands treatment options and represents another step forward in patient-centered IBD care. jnj.com/media-center/p…
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Yuri Gorelik
Yuri Gorelik@GorelikYuri·
Many surprises in this @AGA_CGH meta analysis JAKi no better than placebo for ileal disease Stronger effect of Vedo for ileal than for colonic disease A progress towards positioning in #IBD Will patients with refractory ileocolonic disease benefit from a JAKi+Vedo combo?
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Tauseef Ali MD, FACG AGAF FACP
🔬 JAKing up the options for perianal fistulas in Crohn’s disease! New post hoc analysis from 3 phase 3 trials (U-EXCEL, U-EXCEED, U-ENDURE) shows promising results for upadacitinib in patients with perianal fistulizing CD: ✅ 44.7% of patients on upadacitinib 45mg QD had resolution of drainage at 12 weeks vs 5.6% placebo (p=0.003) ✅ 22.1% had closure of external openings vs 4.8% placebo (p=0.013) ✅ Sustained benefit into 52-week maintenance with both 15mg and 30mg doses ✅ No new safety signals identified 🧠 These findings offer new hope for a tough-to-treat phenotype, especially in biologic-experienced patients. Paper published in @AGA_CGH by @JeanFredericCo1 @RPanaccione @IBD_FloMD and others 📌 Further studies needed to confirm long-term healing with imaging. cghjournal.org/article/S1542-…
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Beatriz Gros
Beatriz Gros@Bealoquebea·
Acute Severe Ulcerative Colitis overview presented by the fantastic Prof Laharie IBD 5 Nations @PGetaid @geteccu @GEDII_IBD
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Denise Young
Denise Young@DDYoung01·
Thought I was doing a peer to peer with a true peer…but the pediatric gastroenterologist on the line did not even know what induction dosing of infliximab was😡 #insurance #medicalmutual #pedsgi #IBD
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PREDICT IBD
PREDICT IBD@PREDICTIBD·
NEW STUDY: HOW DOES MILD IBD PROGRESS OVER TIME? Read our new study in Clinical Gastroenterology and Hepatology, focusing on the often-overlooked subgroup of patients with mild IBD ➡️ cghjournal.org/article/S1542-…
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Beatriz Gros
Beatriz Gros@Bealoquebea·
FC levels show varying correlations with inflammation depending on the specific bowel segment that is affected Patients with #CD assessed by VCE Very useful to have these cutoffs ✅ proximal SB FC>=77 ✅distal SB FC >= 123 ✅ colonic FC>=291 Congratulations, this is a very nice study!
Shomron Ben-Horin@ShomronH

FCP is better for colonic > small bowel (SB) inflammatiin, but how accurate is it in proximal vs. distal SB? Using VCE as gold standard, our @sheba_medical brilliant fellow @OffirU reports in @JCC_IBD a dilutional gradient of calpro along the SB ! pubmed.ncbi.nlm.nih.gov/39120437/

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