
S-CUL3KO model demonstrated impaired renal baroreceptor mechanism leading to hypertension.
Thanks to our collaborators and colleagues!
More on the mechanism of HTN in S-CUL3KO ➡️ insight.jci.org/articles/view/…

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DG
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No pressure—but if the renal baroreceptor machinery piques your curiosity... @curtsigmund & team @MedicalCollege reveal mice lacking CUL3 in vascular smooth muscle cells exhibit robust hypertension with paradoxically unaltered renin expression and decreased integrin β1 expression. See the full report: insight.jci.org/articles/view/…











We congratulate Daria Golosova, MD, PhD, on winning the 2024 Edward J. Lennon, MD, Outstanding Woman Postdoctoral Researcher Award and wish her continued success. Daria received the award from the esteemed Jan Lennon, the sponsor of this honor. @DGphysiology










