Daniel Siegwart

Congrats to Kohki and the rest for our latest publication in Molecular Therapy Nucleic Acids! 🎉🥳Our team discovered that co-transcriptional 2′-OH modifications on synthetic mRNA boost both ribonuclease resistance and LNP thermostability. Read more: sciencedirect.com/science/articl…

Where do cancers start? In the liver, not all cells are the same. The liver is divided into 3 “zones,” and each specializes in different metabolic tasks. We show in @Science that where a mutation occurs in a liver lobule can determine a cell’s fate. science.org/doi/10.1126/sc… (1/9)

The 2025 BME Symposium at UTSW brought together top minds in biomedical engineering! Highlights included Dr. Robert Langer’s Kam Lecture, cutting-edge research on nanotech & cancer therapy, and a powerhouse panel on biotech innovation. #BME2025 #KamFamilyLecture #UTSW #STEM

What a reunion at today’s BME seminar and Kam Family Lecture, featuring Dr. Robert Langer! Dr. Langer is pictured here with four of his lab alum who are all UT Southwestern faculty now. More photos and a recap coming soon!

This #throwbackthursday, we are throwing it back to last Friday to celebrate Graduate Student Researcher Joshua Robinson in the @GDE_UTSW Lab, who successfully defended his dissertation. Congratulations, Dr. Robinson!

Great visit last week to @DJSiegwart, Ph.D., research lab at @utswbme! His groundbreaking work on lipid nanoparticles for alpha-1 antitrypsin deficiency offers hope to thousands affected by this rare genetic condition. Learn more: bit.ly/3G4oWEy

@JudgeClayJ @utswbme Thank you Judge Jenkins @JudgeClayJ ! It was an honor and pleasure to host you and your colleagues at @UTSWMedCenter @GDE_UTSW @utswbme . I look forward to working with you and our community to advance healthcare research that impacts our region and beyond.

Congrats to our team on publishing in ACS Nano! We engineered LNPs to target kidney tumors via vitronectin binding, boosting mRNA delivery 952x in vitro and 42x in vivo. #CancerResearch #LNP #mRNA Read more: pubs.acs.org/doi/full/10.10…

Congrats to Yehui for winning the 2025 Ida M. Green Award at UT Southwestern! Her work offers new hope for cystic fibrosis patients. A true leader in science and the student community! #WomenInSTEM #GeneTherapy #LNP #UTSouthwestern Read more: utsouthwestern.edu/ctplus/stories…

Yehui Sun, PhD candidate in @GDE_UTSW Lab, was presented with the Ida M. Green Award on Friday, July 11 during a small reception. Congratulations to Yehui for her commitment to research excellence, the well-being of fellow students and community service!

The Dallas Morning News recently featured @GDE_UTSW in Rescued by fat bubbles: UTSW scientists treat rare genetic disease with designer molecule. Read the article at the link below.

Rescued by fat bubbles: UTSW scientists treat rare genetic disease with designer molecule dallasnews.com/news/2025/07/1…

Last evening, we were proud to induct the newest class of NAI Fellows into the Academy. The highest professional distinction awarded solely to inventors, this distinction recognizes a lifetime of innovation, impact, and leadership in invention. These scholars have not only advanced knowledge, but improved lives. We were privileged to have Will Covey, Acting Deputy Under Secretary of Commerce for Intellectual Property and Acting Deputy Director of the U.S. Patent and Trademark Office (@uspto), join us to help induct these phenomenal innovators. The newest class of NAI Fellows includes 170 exceptional inventors from 39 U.S. states and 12 countries. Hailing from 135 research universities, governmental and non-profit research institutions worldwide, collectively they hold over 5,000 patents and their work advancing science and technology for the betterment of humanity spans disciplines. Thank you once again to #NAIMemberInstitution @kennesawstate for presenting the Fellows Induction Ceremony at #NAI2025! It is an honor for us to welcome the newest class of NAI Fellows into the Academy. Congratulations to our new Fellows! #Invention #Innovation #NAI2025 #Leaders #Visionaries #AdvancingInnovation

@veiseho @AcadofInventors @cgtraverso @khademh @RiceUniversity @RiceLaunchPad Great friends indeed and so much fun to be inducted and celebrate with you all! @SamuelAchilefu too!

Honored to be inducted into the ⁦⁦@AcadofInventors⁩ today! Especially fun to celebrate with good friends and fellow inductees ⁦@DJSiegwart⁩ ⁦@cgtraverso⁩ ⁦@khademh⁩! ⁦@RiceUniversity⁩ ⁦@RiceLaunchPad⁩!

It was an honor to be inducted into the National Academy of Inventors (NAI) ⁦⁦@AcadofInventors⁩ tonight!

Minigolf Monday Recap! We had a really great time at minigolf with the whole lab crew this Monday! ⛳️🙌 #LabLife

Congratulations to Dr. Minjeong Kim and all additional coauthors!

Our lab’s latest publication in @NatureBiotech led by Minjeong Kim and @DJSiegwart. Read the full story here: nature.com/articles/s4158…

Amogh Vaidya, Graduate Student Researcher in the @GDE_UTSW Lab, successfully defended his dissertation "Development of Organ-specific Lipid Nanoparticles for Delivery of Nucleic Acid Therapeutics" on Friday, May 30. Congratulations, Dr. Vaidya!

Science at #UTSW goes deep – down to the nucleic level. Research led by @DJSiegwart has unlocked synthetic lipid nanoparticles as delivery vehicles for genetic medicines. Explore more in the latest edition of #DiscoveryAtUTSW. bit.ly/43AO6Ej