
Daniel Mark
5.6K posts

Daniel Mark
@DanMarkMD
Physician, cardiologist, cardiac intensivist, Duke University faculty, clinical researcher, EiC American Heart Journal
Durham, NC Katılım Temmuz 2013
2.1K Takip Edilen3K Takipçiler
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“Doctors are not a flock of free-range chickens wandering about offices and hospitals and making up best practices, one clinician at the time,” writes Robert Califf. trib.al/SFpBrTR
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DCRI's Monique Starks is leading this first-of-its-kind study exploring how drones can quickly deliver AEDs to 911 callers faster than emergency services can arrive, improving response times and saving lives.
The Chronicle@DukeChronicle
School of Medicine faculty are using drones to deliver defibrillators to certain cardiac arrest patients. Here’s how they can help you save a life: dukechronicle.com/article/duke-u…
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Initial testing choice between coronary CTA and stress testing for suspected CAD showed no difference in all-cause or cardiovascular mortality among patients with stable symptoms. ja.ma/3Ne8Bk3

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Visual Arts in Contemporary Cardiology:
A review of our article in December’s American Heart Journal ... medicaldialogues.in/cardiology-ctv…

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HOT OFF THE PRESS!
A new Think Tank report outlines the ideal makeup, core skills, and workflow essentials for high-performing CS teams — plus the barriers holding programs back and the opportunities to strengthen clinical pathways nationwide.
Building more reliable, responsive CS teams = better outcomes. ❤️🩹 Read it today: bit.ly/3KlYYia
#CardiogenicShock #CardioTwitter #QualityCare
@BalimSenmanMD @JasonKatzMD @jameshorowitzmd @AnnGageMD @ElliottMillerMD

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Initial testing choice between coronary CTA and stress testing for suspected CAD showed no difference in all-cause or cardiovascular mortality among patients with stable symptoms. ja.ma/47fvIlE

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Jordan Ellenberg on why he went into mathematics rather than statistics.
"I tried. I tried to learn some statistics actually when I was younger and it’s a beautiful subject. But at the time I think I found the shakiness of the philosophical underpinnings were too scary for me. I felt a little nauseated all the time. Math is much more comfortable. You know where you stand. You know what’s proved and what’s not. It doesn’t have the quite same ethical and moral dimension that statistics has."
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✅✅ A reminder by Dr. Rahaf Ajaj:
She wasn’t on the Stanford list… but she made it to the Nobel stage. 🏅
Mary E. Brunkow, one of this year’s Nobel Prize winners in Medicine, has only 34 published papers and an H-index of 21.
She never appeared in Stanford’s ranking of the world’s top 2% of scientists.
She didn’t chase citations, metrics, or the spotlight.
Yet, she became part of a discovery that changed how humanity understands the immune system.
Today, while many are busy chasing numbers, titles, and rankings —
she reminds us what truly matters in science: the question.
🔹 She wasn’t running after the lists.
🔹 She was running after the truth.
Because in the end, it’s not about how many papers you publish…
It’s about how deeply your idea can reshape the world.
Focus on your idea, not your ranking.


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Happy to share our new editorial for the @BJSM_BMJ on the interpretation of statistical estimates and P-values!
doi.org/10.1136/bjspor…
@Mohamma70696197 @StevenStovitz @Lester_Domes

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#ICYMI: Health Status by Revascularization in ISCHEMIA #AHAJournals @DanMarkMD @GreggWStone @W66588221White @webmd11
@SripalBangalore @chetanhuded
Circulation@CircAHA
In ISCHEMIA trial, invasive management with either PCI or CABG led to better long-term QoL than conservative management ahajournals.org/doi/full/10.11…
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"I've done it!" On 16 September 1977, Andreas Grüntzig made history: he carried out the first #angioplasty, and changed the lives of millions of patients forever.
Standing on the shoulders of the giants that came before him, his vision and determination drove an entire new field of cardiology: Interventional Cardiology
Listen to this description of his incredible journey by Jean Marco, who knew him and was also a pioneer in the field. Jean Marco carried out his first angioplasty in 1979 and was inspired by Gruntzig's example to launch a LIVE demonstration Course in 1982.
This ultimately paved the way for the first PCR Course in 1989, founded with Jean Fajadet in Toulouse, and gave birth to PCR as we know it today.
From the legs to the coronaries: How Andreas Grüntzig reached his dream 📺 🎧 pcronline.com/About-PCR/hist…
(interviewed by @kiadeb87 )
More about the history of PCR here 🔗 pcronline.com/About-PCR/Who-…
#interventionalcardiology #medicalhistory #interventionalcardiologist #cathlab

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Trajectories of Angina After Initial Invasive vs Conservative Strategy for Chronic Coronary Disease: @JACCJournals
🥸"A greater proportion of conservatively managed patients experienced unfavorable angina,..., compared with those treated invasively.": @djc795
👇👇👇

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🚨 New paper out in JACC!
We examined angina trajectories in the ISCHEMIA trial—how patients’ symptoms evolved over 2 years after an initial invasive vs conservative strategy.
jacc.org/doi/10.1016/j.…
👉I’ll summarize the key findings in this thread.
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Truth starts with accurate words. 'Emulate' means to copy. Target trial emulation does not copy RCT design other than defining the inception cohort. It does not copy randomization, blinding, prospective data collection, specifying adjustment variables before collecting data ..
NonsparseOncologist@5_utr
“Emulating” RCTs is disastrous language applied to an infeasible situation - how does one emulate blinding? randomization? The old observational data is dressed up as the new “emulated RCT” Marketing terminology and salesmanship is all this is imho @RWJE_BA
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The countdown is on! DANFLU-2 will be presented at #ESCCongress on Saturday!
332,438 adults ≥65 years 👵👴
High-dose vs standard-dose influenza vaccine 💉
Severe outcomes: hospitalizations and deaths 🏥☠️
Design paper: bit.ly/47P65ZE
Look out for simpubs! 👀

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Fact and fiction in statistics larspsyll.wordpress.com/2025/08/20/fac… via @LarsSyll
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Those teaching basic or general concepts for applied statistics may be interested in the new post at arxiv.org/abs/2508.10168
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• A minority of post-MI patients with LVEF≤35% ever need their primary prevention ICD.
• Pharmacotherapy has advanced since previous trials for primary prevention ICD
•Our PROFID trial will reassess the role of primary prevention ICD post-MI.
sciencedirect.com/science/articl…
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