Dani

#Whey Protein Ingestion Stimulates #Glucagon Secretion and Raises Blood #Glucose Levels in Adults With #T1D diabetesjournals.org/diabetes/artic…

“As exercise intensity increases, ATP demand rises sharply and glycolytic flux accelerates. At some point, mitochondria cannot oxidize pyruvate fast enough to match the rate at which it is being produced. The system requires a solution. That solution is the reduction of pyruvate to lactate, which regenerates NAD⁺ and allows glycolysis to continue. Lactate production is not a failure of the system. It is its solution to a fundamental redox constraint, the mechanism that sustains ATP production when glycolytic flux exceeds mitochondrial processing capacity. In addition, lactate carries with it a proton from the cytosol, contributing to a temporary buffering of intracellular acidity”. @inigosanmillan/note/p-193581258?r=2nunp3&utm_medium=ios&utm_source=notes-share-action" target="_blank" rel="nofollow noopener">substack.com/@inigosanmilla…

Clinic for Athletes With Type 1 Diabetes: Evaluation of a Structured Clinical Care Model for... - goo.gl/scholar/hnHKtP #ScholarAlerts

This nationwide study demonstrated that among adults with type 1 diabetes, continuous glucose monitoring users had lower rates of both acute and chronic diabetes-related complications and mortality than non-users #CGM #T1D link.springer.com/article/10.100… 🔓

🚨New Substack Article: VO₂max vs Lactate VO₂max represents cardiorespiratory adaptations and measures oxygen delivery. Lactate reflects cellular and mitochondrial adaptations key for metabolic health. Over the past decades, elite sport moved beyond VO₂max and focused on metabolism. That shift changed how we interpret physiology, how we train and how we define performance Longevity and metabolic health are now arriving at the same crossroads. Because improving how we deliver oxygen is only part of the equation. Understanding how our cells use it is what ultimately determines metabolic health 👇 inigosanmillan.substack.com/p/vomax-vs-lac…

SON ARGENTINAS. Lo defendemos siempre y en todos lados. Al mandarme a Francia, @JMilei me dio un mandato claro: potenciar la relación bilateral y defender nuestros intereses. Cualquier argentino de bien hubiese hecho lo mismo.

In this real-world study, teplizumab treatment improved HbA1c, OGTT and CGM measurements within the first year of therapy. The preproinsulin targeting T cell receptors decreased after the treatment, which correlated with C-peptide AUC link.springer.com/article/10.100… 🔓#T1D

#muscles appear to love #daylight! Helps #improve #glucose control and whole-body substrate metabolism in #T2D: Cell Metabolism cell.com/cell-metabolis…

@MCRiddell1 Not considering some CGM reads above (Zone A), some within (Zone P) and some below (Zone B) true physiological glucose exposure? Want to find out which Zone your CGM reads? theglucoseneverlies.com/faq-cgm-regula…

We are looking for #T1D (in the United States only) who might be interested in #exercise education specifically for those with #T1D.

Lots of #Hypoglycemia during free‐living physical activity in adults with #T1D using #AID: Results from the RAPPID study - 2025 - Diabetes, Obesity and Metabolism - dom-pubs.onlinelibrary.wiley.com/doi/full/10.11…

New in the January Issue: Staging #prediabetes and type 2 #diabetes: the time to start is now thelancet.com/journals/landi… #T2D

⚽️Science is on the pitch!🔥 Glycemic differences between active and reserve players of the @UEFA Champions-League: ⏱️During the match: ⬆️ Glycemic levels ⬆️Time above range ⬇️ Time in range 👉Even healthy athletes show mild hyperglycemia. 🔗doi.org/10.1177/193229… Great job!💪

Level 3 #hypoglycaemia remains common in #diabetes!. @AlexR_L and team demonstrate Real‐world incidence and risk factors of level 3 (severe) hypo: dom-pubs.onlinelibrary.wiley.com/doi/10.1111/do…

20 years ago, measuring fat and carbohydrate oxidation rates in the lab with elite athletes, I began recommending 80–100 g/h of carbohydrate intake during endurance events. At the time, this was considered impossible according to the existing scientific consensus and I faced strong criticism for it as it was a crazy concept… 15 years ago, I started implementing up to 125 g/h, this time without saying much. Now, two decades later, new research confirms that athletes can indeed oxidize around 120 g/h which I was already observing in the lab and applying to endurance athletes many years ago. It’s fascinating to see how science evolves. Sometimes what’s called “impossible” simply needs time to be understood… journals.physiology.org/doi/abs/10.115…

Exercise Intensity Terminology is a bit of a mess 😵‍💫 Our attempt to try & summarise some of the different approaches, and make some recommendations going forward, has finally been published in both MSSE: bit.ly/4nT7Pq5 & JSaMS: bit.ly/46U7ptq.

Got #T1D A 20-minute walk can do what insulin alone sometimes can’t - Get you back into range Rapidly! “20 by 2mmol/L” or "20 by 40 mg/dL" Walking is ideal, but any enjoyable movement counts Avoid if glucose if ketones present Study: onlinelibrary.wiley.com/doi/10.1111/dm… Resources theglucoseneverlies.com/20-by-2/ Thanks @MCRiddell1 @5Dess Zoey Li Robin Gal Peter Calhoun @WilmotEmma @parthaskar @drpratikc @nickjonas @JamesNortonBlog @Irun4T1D @d_albrittain @AKoutnik

Lactate is NOT the responsible for acidosis. Its production is intimately intertwined with mitochondrial function. Proper lactate clearance capacity ➡️ proper mitochondrial function➡️ metabolic health. 🧵👇

Impact of an Insulin Bolus Calculator on Glycemic Control in Relation to Exercise—A Crossover... - goo.gl/scholar/gwy9HS #ScholarAlerts

🧵 Exercise significantly improves sleep in insomnia Useful for some of us 😜 🏆 Most effective: 1. Yoga:↑ total sleep time 2. Tai Chi:↑ sleep quality & ↓ night wakening 3. Walking/jogging:↓ insomnia severity ✅ Safe, scalable & non-pharmacological ebm.bmj.com/content/early/…