Michael Rockman, MD, PhD

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Michael Rockman, MD, PhD

Michael Rockman, MD, PhD

@DataExplorer21

Cardiology Fellow @uw_cvm 🫀@hERGologie lab 🔬Physician-scientist studying ion channels in arrhythmia 🤓

Madison, WI Katılım Ekim 2018
9.3K Takip Edilen8.5K Takipçiler
Michael Rockman, MD, PhD retweetledi
Paul Carr
Paul Carr@PaulCarr·
The World Cup final’s jersey matchup is perfect. Spain’s red vs Argentina’s blue-and-white. Good work, everyone! 🇪🇸🇦🇷
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Eric Topol
Eric Topol@EricTopol·
At least 10% of the population has a significantly elevated Lp(a) above 50 mg/dL (~125 nmol/L), which carries an increased risk of atherosclerotic cardiovascular disease. While we've known that for decades, we've never had a drug to treat it. There are 5 programs in advanced trials (Table below, 3 in phase 3, pivotal, CV outcomes as endpoint). We may see the results for the first drug (pelacarsen) soon, by end August, and FDA approval is expected in 2027. This likely represents a major advance for preventing heart disease, adding to the first oral PCSK9 blocker approved this week.
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Dr. Catharine Young
Dr. Catharine Young@DrCatharineY·
The science strongly supports ending the twice-yearly clock changes. Where the debate begins is which time should be permanent. Most sleep and circadian experts favor permanent standard time, not permanent daylight saving time, because morning light is the strongest cue for aligning our biological clocks. As @hubermanlab has noted, we often confuse what feels good (later sunsets) with what is biologically optimal (earlier morning light).
Breaking911@Breaking911

BREAKING: The House has passed legislation to make Daylight Saving Time permanent nationwide, ending the twice-a-year clock changes by a 308-117 vote. Backed by President Trump, the bill now heads to the Senate. If approved and signed into law, Americans would no longer have to change their clocks.

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Brad Gerstner
Brad Gerstner@altcap·
A tragic reminder - get your CAC scan - the mammogram for the heart. Cardiac arrest / heart disease is the #1 killer & largely preventable. $150 & 15 mins to save your life. In honor of Sen. Graham we should immediately cover w insurance & launch a natl ad campaign. 🤍 @DrOz
OSINTdefender@sentdefender

Senator Lindsey Graham (R-SC), appearing overall outwardly healthy, spoke to reporters yesterday in the Ukrainian capital of Kyiv, expressing support for the White House’s decision to impose tougher sanctions on Russia. Roughly 24 hours later, he was dead from sudden cardiac arrest at his home in Washington.

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Michael Rockman, MD, PhD retweetledi
Brandon Luu, MD
Brandon Luu, MD@BrandonLuuMD·
Sleep deprivation makes people less willing to help others. In this study, a single night without sleep reduced people’s desire to help, even friends. At the societal level, donation amounts dropped ~10% after the spring daylight saving time sleep loss.
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Monica Verduzco-Gutierrez, MD
Monica Verduzco-Gutierrez, MD@MVGutierrezMD·
As a PM&R brain injury doc, I cringe every time I see a soccer header.
 Not because it looks dramatic, 
but because even routine headers cause measurable brain injury. 🧠⚠️🧵1/
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AHA Science
AHA Science@AHAScience·
Published today, AHA/ACC/ESC/WHF Expert Consensus Document: Second Universal Definition of Heart Failure (HF) (2026) professional.heart.org/en/science-new… ✍🏼 @MinnowWalsh @KarenSliwa @amibanerjee1 @BiykemB @akshaydesaimd @DukeHFDoc @MKIttlesonMD @lamcardio @WilfriedMullens @NutritionHF 📷 Trajectories of HF. An individual’s HF journey starts left to right, and quality of life or exercise capacity and prognosis become poor as HF stage advances. Every stage carries certain risk of sudden death.
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nature
nature@Nature·
Nature research paper: Small-molecule modulation of β-arrestins go.nature.com/4baTqB4
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Michael Rockman, MD, PhD
Michael Rockman, MD, PhD@DataExplorer21·
"In a tough negotiation, a public debate or an investment pitch, for example, surround yourself with supportive co-workers. Rely on a colleague to give you a warm introduction when you speak at an event and ensure that a buddy greets you after." @Nature nature.com/articles/d4158…
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Lexie Mannix, MD
Lexie Mannix, MD@ALMannixMD·
The ED isn’t overwhelmed because it’s inefficient. It’s overwhelmed because it’s functioning exactly as the backup plan for a broken system.
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Ahmed Bennis MD 🫀
Ahmed Bennis MD 🫀@drbennisahmed·
URGENT ALERT: U.S. HF –related mortality is back on its pre-pandemic upward trajectory 📈 +1.9%/yr since the 2012 nadir This needs urgent prioritization: ✅ Enhanced prevention ✅ Early diagnosis ✅ Rapid optimization of GDMT ✅ Adherence and coordinated longitudinal care
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Eric Topol
Eric Topol@EricTopol·
We stress tested many frontier AI models for multimodal medical reasoning (including GPT-5, Claude 3.5, Gemini 2.5 Pro). They’re not ready. Faulty reasoning, use of inappropriate shortcuts, hallucinations. Published today @NatureMedicine nature.com/articles/s4159…
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Eric Topol
Eric Topol@EricTopol·
A very impressive discovery of a new ECG marker for sudden cardiac death validated in 3 different cohorts and linked to benefit of defibrillator, an outgrowth of human research ingenuity and AI deep learning nature.com/articles/s4158…
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Sara Moscatelli
Sara Moscatelli@saramoscatelli7·
New paper alert 📢 A fascinating new study from the Padua group examines 40 years of sudden cardiac death (SCD) in competitive athletes due to arrhythmogenic cardiomyopathy (ACM) and highlights how the phenotype of disease is changing over time.  Key takeaways: 🔹 ACM remains the leading cause of SCD in young competitive athletes, accounting for almost 29% of cases in this national referral centre experience.  🔹 The incidence of ACM-related SCD in athletes has decreased significantly over time, likely reflecting improved awareness, screening strategies, and implementation of diagnostic criteria.  🔹 A striking phenotypic shift towards left ventricular ACM (LV-ACM) was observed. After 2010, LV forms represented a much larger proportion of cases, while classic right ventricular forms became less common.   🔹 Traditional screening tools may miss these patients: •ECG abnormalities were present in only around half of cases. •Echocardiography was positive in very few athletes. •LV-ACM frequently showed normal or borderline ECG and echocardiographic findings.   🔹 Exercise-induced ventricular arrhythmias and low QRS voltages emerged as important warning signs that should prompt further investigation.  🔹 The study reinforces the growing role of contrast-enhanced cardiac magnetic resonance (CMR). In athletes with suspicious findings, CMR may identify myocardial fibrosis and late gadolinium enhancement even when echocardiography is normal.  💡 Clinical message: As ACM evolves from a predominantly right ventricular disease to a more frequently recognised left ventricular phenotype, reliance on ECG and echocardiography alone may be insufficient. A high index of suspicion and timely use of CMR are essential to improve early diagnosis and prevent sudden cardiac death.  #Cardiology #SportsCardiology #CMR #CardiacMRI #ArrhythmogenicCardiomyopathy #ACM #SuddenCardiacDeath #SportsMedicine #CardiovascularImaging #PediatricCardiology #InheritedCardiacConditions
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Bryan Carmody
Bryan Carmody@jbcarmody·
Big Signaling is the cure for Application Fever.
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