Davison 🧠👈

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Davison 🧠👈

Davison 🧠👈

@DavisonVideo

Model, pundit and producer of online video; #Medicine and #Longevity boo. Funny but annoyed. https://t.co/sILNsWCUKH https://t.co/TvfI1F8YX1

Canada Katılım Eylül 2009
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Davison 🧠👈
Davison 🧠👈@DavisonVideo·
Another episode of me reading ai erotica generated by grok and then acting it out. I call it grokrotica! ☺️
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Dr. Jebra Faushay
Dr. Jebra Faushay@JebraFaushay·
Someone needs to tell Debbie Gibson that the cut-off age for wearing a onesie is two years old. (CharmaineAdams)
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Davison 🧠👈 retweetledi
L. Amber O'Hearn
L. Amber O'Hearn@KetoCarnivore·
"Preferred fuel" is a red herring here. It's a technical term meaning it has oxidative priority. Being "preferred" would not imply that the body tries to make sure it always has ketone bodies (KBs) under any macro context. But is it the best fuel? Is it at least as good as glucose? Yes, it's absolutely true that glucose is in a fundamental and cross-species way a basic fuel for brains in maintenance, while developing brains even in many other species, but especially in humans, normally require KBs. Hence their elevation in placenta, and late pregnancy transfer, and the ketogenic state of newborns, the ketogenic propensity of breastfeeding, and the role of adipose tissue in human babies. Hence their presence even overnight in many cases up through adulthood. Hence their ability to help repair neurodegeneration. KBs are important for neuroplasticity, and humans are unique in having a brain development trajectory that spans decades after birth. I don't understand how anyone could make a serious argument that it's "not clear whether our ancestors had experience with ketogenic diets", and then implicitly cite modern HGs as evidence. First of all, all modern subsistence strategies, from very high carb to very low, are solutions to the problem of (likely self induced) loss of megafauna. For the majority of the 2 million years of homo erectus and early modern humans, we lived primarily on fatty meat with little to no regular digestible carbohydrates. What choice would there be but to be in ketosis much of that time? It simply would not have been possible to support the human brain on the combination of available digestible carbohydrate and the limited gluconeogenic capacity we have due to our specific provenance. And this long exposure to this subsistence situation is reflected in many of our physiological adaptations—adaptations that reflect high reliance on a fat-based metabolism, many of which I've written about elsewhere. As to the specific modern HGs mentioned, it is nothing short of disingenuous to mention that Arctic genetic variants "suppress ketogenesis". As I've written about before, the genetic variant that somewhat *inhibits* ketogenesis was only possible because the traditional food environment was so high in HUFAs that it drastically increases ketogenesis, such that lower ketogenesis was possible while still being in significant ketosis. The adaptation had the advantage of actually allowing ketosis to persist on the face of higher protein intake. Critically, the same genetic change equally inhibits gluconeogenesis, so if you argue that these populations had no ketosis on their traditional diet then you must also imply they had no significant GNG. So how did they fuel their brains!? No. Traditional diet permitted plenty of ketosis. That myth has to die. As to Maasai, there is contention around their diet. I have personal friends who visited a few decades ago and insisted the diet was essentially plant free for everyone. I have not been there and there is not consensus and it's probably different now, so I will not insist a particular story about it. Nonetheless, I must reiterate that modern HGs are *not* a suitable proxy for our evolutionary past. Wild game today is not high enough in fat to support the modern human physiological architecture and so we do what we can to maximize fat yield from domesticated animals and supplement with digestible carbohydrate that we've learned to grow as well. This works. But none of this means that we can't survive and thrive perfectly well in long term ketosis when food sources allow. It is our heritage.
Chris Masterjohn@ChrisMasterjohn

If ketones were the “preferred fuel of the brain” then a mixed diet with any proportion of macros would maximize ketone delivery to the brain. The fact that you need to restrict carb to get ketones appreciably into the brain shows that the brain runs primarily on carbs whenever they are available and therefore prefers carbs. The facts that ketones are as effective as drugs at increasing GABA (we know this because properly executed ketogenic diets are as antiepileptic as drugs), that abnormally high concentrations act as highly effective anesthetics through direct actions on glycine and GABA receptors, and that they extend the efficiency of ATP utilization are all consistent with being in energy conservation mode. Ketones are a normal part of normal metabolism. Even on a mixed carbohydrate-inclusive diet you tend to make about 140 Cal worth of ketones per night. They elevate after an overnight fast, in a newborn infant, and in late pregnancy. But the normal, natural state of ketones rising to become the major fuel of the body is fasting. It is not clear whether our ancestors had much experience with ketogenic diets. Surely they had experience with fasting during famines or during intentional rituals. Surely they had variation in carbohydrate availability. But in extant hunter gatherers, plant foods increase according to their availability. At the equator, maximal choice is present and foods are about half plant half animal. In the far North, you have genetic adaptations that suppress ketogenesis despite having minimal plant availability. In groups like the Maasai, the widely popularized “milk and meat” diet was only for male teens during a highly regulated ritualized life stage where they traditionally also went on marches for wild honey and never ate meat without copious use of antimicrobial teas. But the actual broader diet has always involved extensive trade with neighboring tribes to include starches. Even milk provides plenty of carbohydrate. So their diet was probably usually not ketogenic, but maybe mildly ketogenic for male teens. The overwhelming difference with ketones is that they increase GABA signaling and extend ATP efficiency. The first lowers energy expenditure and the second conserves energy by making it used more efficiently. The first is like driving less and the second is like getting better gas mileage. These are the two features you expect during weight loss! This is highly consistent with ketones being primarily a signal of the extended fasting state. The invention of the ketogenic diet to treat epilepsy in 1921 was an ingenuous biohack that allowed this “slow down the nervous system” signaling to be complemented by a high calorie intake, signaling robust energy availability and thereby countering energy conservation and bringing up not only long-term sustainability but also the feeling of well being that comes with being well nourished.

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🇨🇦Ellegar Garbae 🏒
@NoFilterSkin Girl if you have a wine for the 1st time in 2 months and you are ugly 3 days later.. I hate to break it to you but it’s not the wine.
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No filter Skin
No filter Skin@NoFilterSkin·
Alcohol is the worse drug on the planet. I wish it never existed. We live in a generation of functioning alcoholics. Drinking multiple times a week. It’s sad. Alcohol literally makes you ugly.. I drank alcohol last weekend for the first time in 2months and i looked ugly for 3days after that. I felt ugly too btw.
Dammy Esquire.,@Dammi_Esq

Name the foods and drinks that can be hazardouss to our health but are consumed daily. Health education post.

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DaBearschik1981
DaBearschik1981@FischerChr96042·
@Ani_Cameo @CTVNews when I asked my doctor, what to take she told me to take vitamin D and calcium that’s it. And my bones and joints don’t hurt anymore.
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Ani
Ani@Ani_Cameo·
@CTVNews The disinformation is woman being prescribed Estrodial & HRT which increases risk of cancer among other side effects . Menopause sucks but with some natural supplements & correct diet it’s manageable .
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Davison 🧠👈
Davison 🧠👈@DavisonVideo·
@newstart_2024 This is the opinion of ONE white, male psychiatrist. It is NOT this stark nor is having higher emotional sensitivity a hindrance to all kinds of accomplishments.
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Camus
Camus@newstart_2024·
Dr. Daniel Amen just dropped a fascinating brain scan insight on Chris Williamson’s podcast. Women overall have healthier brains with stronger frontal lobes. But their emotional centers (limbic system) run hotter — leading to more rumination and a higher tendency toward depression. This one made me stop and think. That extra emotional wiring makes perfect sense for bonding and caretaking, yet it comes with real costs. No society has flipped the primary caretaker role, which says something deep about biology. Understanding these natural differences could help us approach mental health, relationships, and expectations with more compassion instead of pretending we’re all wired the same. Do you think we talk enough about these brain differences between men and women, or does it still feel too taboo?
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Davison 🧠👈
Davison 🧠👈@DavisonVideo·
This is false; you both have to like each other enough. Few people get that the majority of dissatisfying relationships are when there's a discrepancy between who likes the other more. I'm not gonna pretend that there aren't difficult seasons in long-term relationships but it's not that he has to like you more or she has to like you more, you both have to like each other enough.
Degen CPA@DrewVento

For relationships to work the girl has to like you more than you like her

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Crémieux
Crémieux@cremieuxrecueil·
Increasingly many studies are showing that GLP-1RAs seem to slow down cancer growth!
Crémieux tweet media
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Matthew Harrison △
@DavisonVideo @cremieuxrecueil Totally irrelevant unless you've got something specific to point to. All of the current side effects are short term and minor. As for the lung term side effects, they only keep discovering unintended protective properties.
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Davison 🧠👈
Davison 🧠👈@DavisonVideo·
@matt96h @cremieuxrecueil Few drugs are all good or all bad and most drugs have side effects. Both dosage and length of exposure determine deleterious effects.
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Matthew Harrison △
@cremieuxrecueil Wow, are these the "unknown long term side effects" I've heard everyone fear monger over? Truely horrifying stuff. These people are FOOLS.
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Davison 🧠👈
Davison 🧠👈@DavisonVideo·
@internetuserf12 Not only was it oppression in the case of Covid, it was unnecessary punishment for the unvaccinated. Ebola isn't the same virus.
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Mazi Chukwuemeka Aneke
@BBCNews Rising cases like this show how lifestyle and environmental exposure are quietly shaping long-term health trends.
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Davison 🧠👈
Davison 🧠👈@DavisonVideo·
@BBCNews This is inaccurate medical reporting because they have proven that melanoma is closer to a leukaemia than a traditional UV driven skin cancer like a basal cell carcinoma. Melanoma isn't caused UV light exposure and they've proven it: academic.oup.com/bjd/article/19…
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Davison 🧠👈
Davison 🧠👈@DavisonVideo·
@MonicaMAlmaguer You are out of your melon if you think the written word is more explicit than videos. Please!!! 😂😂😂
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Monica Almaguer
Monica Almaguer@MonicaMAlmaguer·
Is this porn? Because society can't simply point the finger at guys, without also calling out women who happen to consume erotic content through different means. Personally I think it's "worse"..it involves ACTIVELY creating the scene with her imagination. While men passively consume.
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jezz
jezz@JezziiB·
It's been awful watching some of my former guy friends become men who prey on younger women. Saying things like women in their 40s are angry & bitter so they "have" to date women 28-32, or younger, because they have less trauma. And I'm like: Dude, YOU are the trauma.
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