Deeban R, PhD

Our summary on each RCT to date on hypoglossal nerve stimulation and AHI in Sleep Apnoea. Good news: consistent AHI reductions, strong safety, durable 5-year outcomes, and favourable cost-effectiveness. The caveat: the RCT base is still thin. Small cohorts, responder-enriched designs, and short follow-ups that limit generalisability. For context, the GLP-1/GIP agonist tirzepatide (SURMOUNT-OSA) showed AHI (apnea-hypopnea index) reductions of -25 to -29 events/h across two phase 3 RCTs. The best HNS trials sit around -14 to -16. We need more trials, but the direction is promising. Published in @journal_CHEST Open access ↓ authors.elsevier.com/sd/article/S00… @KingsCollegeLon @GSTTnhs

@tehMoonwalkeR Looking forward - wasted 3 hours the other day on One Battle After Another, which was objectively terrible.

This is a masterpiece, i laughed and cried a lot, half of the cinema joined me. We need to support innovative movies again, less fan service, more actual effort

@MarioNawfal Beyond me that he's even driving his own vehicle during a world tour.

🇺🇸 The worst part of JT's DUI ordeal? When the cop doesn't know who Justin Timberlake is 😂 Source: CNN

@DailyMail 😂😂😂 war torn lol

I was in war-torn Dubai for the last two weeks, this is what I saw... trib.al/Ba29gCt

@not_jeffepstein ahahahah

Hello it’s Palm Beach Pete just another perfect day in South Florida, off to play some tennis!… I’m not Jeffrey Epstein.

@Chasetherabbit @RyanDetrick 😂

So many of these, but this one is a classic Chuck Norris joke. 🐅 #RIPChuckNorris

@MarieIsabellaB @LibertyCappy 😂😂😂

@LibertyCappy 🤣🤣

CHUCK NORRIS MEME THREAD TO END ALL MEME THREADS Let's honor one of the GOAT's by dropping your BEST Memes and Chuck Norris jokes! 👇👇👇

@gcfascist @not_jeffepstein 😂😂😂

@not_jeffepstein this is exactly what Jeffrey Epstein would say and do. I don't buy it

Hello this Palm Beach Pete just wanted to thank everybody for the support and good vibes… I’m not Jeffrey Epstein

@not_jeffepstein The witness protection program looked at this account and said we didn't approve this.

🕊️ Chuck Norris has died at 86. tmz.me/N3EVxQe

@cardoni @ExxAlerts 😂

@ExxAlerts “Palm Beach Pete” somehow sounds even worse than “Jeffrey Epstein”.

NEW: Man who went viral for looking like Jeffrey Epstein speaks out. "I'm not Jeffrey Epstein, I'm Palm Beach Pete."

@ExxAlerts That’s definitely Jeffrey

@perplexity_ai So cool

Perplexity Computer now connects to your health apps, wearable devices, lab results, and medical records. Build personalized tools and applications with your health data, or track everything in your health dashboard.

@DefiantLs 😂😂😂

Florida man speaks out: "I am not Jeffrey Epstein" "My video went viral because some dude randomly filmed me while I was driving"

@0xGSD Awareness is growing which is positive, because fixed exist with strong enough research. That’s part of what we’re working on in the lab.

@Deeban On the positive side, there is push back on this. It'd be worse if people were ignorant of the threat this poses

A year ago, we were being criticised on Spaces for saying AI safety was a real issue. "Just change the prompt." "App layer fixes it." "Use a better model." I have the receipts, total nonsense. Now Anthropic is suing the Pentagon over safety red lines, its CEO questions whether models may already be conscious, and 150+ AI leaders are marching in San Francisco tomorrow. That number will grow exponentially. This time last year, there were just a handful of us protesting. The problems are industry-specific, they're getting worse, and prompt changes or broad guardrails don't solve them. The solution runs far deeper than prompt engineering - and much more open, transparent research is needed. x.com/sentdefender/s…

@trussliz Truly horrific.

This is completely horrific. It shows the depths to which Britain has sunk.

@kokoski @DioneProtocol Congrats @kokoski Well deserved 👏

After dedicating my time towards @DioneProtocol since August 2022, I'm stepping back to focus on new ventures. I could write 10,000 words explaining why what we built at Dione is unreplicable by 99% of crypto founders. But I’ll just show you the receipts instead. BEFORE AI made coding accessible to the masses, here’s what we delivered. Study it. Because what I build next will make this look like a warm up. THE FOUNDATION: Fair-launched $DIONE on Ethereum in August 2022 (bear market bottom). Then we did what 99% of projects talk about but never do: We built our own Layer 1 blockchain. Complete migration. Testnet + Mainnet deployed. Odyssey L1 is live. THE INFRASTRUCTURE: ✅ Full L1 stack: Explorer, Portal, RPCs, Faucets, Network Monitors ✅ 3 wallet types: Mobile (WalletConnect, 2FA, biometrics), Browser, Staking Extension ✅ Dual bridges: Token + NFT (Ethereum ↔ Odyssey, fully functional) ✅ Staking V1: 345M+ $DIONE staked at peak. 1% monthly rewards. ✅ NFT ecosystem: 2,500+ Elysium 88 NFTs, yield farms, staking multipliers ✅ Vesting tracker, Odyssey Name Service, OdysseyGo SDK ✅ 15,000+ on-chain users ✅ 50,000+ CEX users ✅ All successfully audited by crypto’s #1 security firm, Hacken, with ZERO exploitations or issues. THE BREAKTHROUGH: ✅Orion Solar Validators - World’s first AI-powered solar-based remote validators. Proprietary green energy detection. DePIN infrastructure. Live in beta. THE ECOSYSTEM: ✅AmaraSwap: Perpetual DEX for carbon credits (exclusive to Odyssey mainnet) ✅Dione Portal ✅Dione Bridge ✅Ozma: AI co-pilot for crypto education (live) ✅Cre-8: Launch platform (testnet live) THE INTEGRATIONS: ✅ DEXTools ✅ Alchemy Pay ✅ PawChain ✅ Tangem ✅ Gate Io ✅ Mexc ✅ LBank ✅ Bitmart ✅ XT ✅ Biconomy ✅ CoinDCX ✅ Zebec ✅ CMC ✅ CG ✅ Ethereum wrapped token THE COMMUNITY: 📊 120,000+ on X (organic) 📊 200,000+ across Discord/Telegram (real people) 📊 Trended globally on X multiple times (millions of impressions) 📊 Fox 5 TV coverage 📊 Top 400 crypto ranking in 10 months 📊 Token2049 attendance 📊 Dione x BRETT x Zebec Yacht 📊 Consensus attendance 📊 Paris Blockchain Week attendance 📊 Binance AMA (13K+ viewers) Fair distribution from day one: - <5% team/supply control - No VC dilution - No dumps on holders - Fully decentralized HOW WE FUNDED ALL OF THIS: 2% trading tax. That’s it. Paid for: - Payroll (entire team) - Marketing (global campaigns, influencers, Meta ads with 15M impressions) - Development (50+ deliveries) - Operations (everything) ACCELERATIONS: ✅ Accelerated the growth of OVPP providing early stage funding, community growth, presale hosted, airdrop campaign hosted, social media support, development resource support, and strategic consultation. THE TRACK RECORD: ✅ 100% delivery rate maintained across 3.5 years ✅ 50+ deliverables shipped on schedule ✅ 15 major releases in single months ✅ Survived 2022 bear as one of the strongest ETH projects ✅ Migrated to L1 with 1:1 fairness (how many projects pulled this off?) ✅ Known as one of the strongest projects of all time on Ethereum THE REALITY: - Most projects promise the world and deliver nothing. - We delivered a full L1, DePIN hardware, 6 live products, 15K users, 320K community members, global integrations, and a sustainable business model. - All without taking a single dollar from VCs. WHERE WE ARE NOW: - The team remaining is strong. The infrastructure is built. The products are live. - Odyssey L1 is operational. The vision continues. - The team is actively working on handing off the Baton to the community to transition to a FULL Governance model on-chain WHERE I’M GOING: I’m stepping back to build what’s next, which may or may not be Web3 related. To the founders watching: This is the standard. To everyone who supported from day one: You know what we accomplished together. Grateful. To everyone watching what’s next: Stay tuned. BK.

ai emergence lab

@mickal @Tekeee 😂

@Tekeee x.com/mickal/status/…

Dubai real estate is cooked People are selling all their properties

@shanaka86 If you dislike Dubai for these reasons, have fun in Saudi lol

Dubai intercepted 96 percent of what Iran launched last night. Then it arrested people for filming the 4 percent that got through. The UAE’s air defense network is extraordinary. Patriot PAC-3 for short and medium range. THAAD at Mach 8 for high-altitude ballistic intercepts. Barak-8 for naval and land threats. AI-powered target classification sorting fibre-optic drones from ballistic warheads in milliseconds and assigning the correct interceptor tier before a human operator could identify the track. Since February 28, UAE systems have engaged 314 ballistic missiles and 1,672 drones. The interception rate across the campaign runs between 90 and 96 percent. That is world-class. That is lives saved. That is technology performing under conditions no peacetime simulation could replicate. And then the UAE arrested a 60-year-old British tourist for filming a missile strike and sending the video to his family. He deleted it. They charged him anyway. At least 21 foreigners have been charged under cybercrime laws for possessing, posting, or privately sharing photos and videos of the attacks. Survivors who sent proof-of-life images to their families have been detained. The minimum penalty: two years in prison, fines up to $54,000, and deportation. A country that intercepts 96 percent of incoming warheads is now telling the world that the 4 percent it cannot stop is too dangerous to photograph. The message to every tourist, every expat, every international investor considering Dubai is not “we are safe.” It is “we are safe, and if you document any evidence to the contrary, we will put you in prison.” That message is doing more damage to Dubai’s brand than the missiles. The same week, Reuters reported that the UAE is one of six Gulf states actively pressing Washington not to stop short but to fully neutralise Iran’s military capability. Abdulaziz Sager of the Gulf Research Center confirmed: Iran crossed every red line. The UAE wants the war to end with Iran permanently unable to threaten the strait. That pressure is understandable. Dubai has been struck repeatedly. Fuel tanks at the airport ignited. Flights suspended. Fertiglobe, one of the world’s largest nitrogen producers at 6.6 million tonnes annual capacity, sits on soil that is under persistent bombardment. But here is the strategic irony the UAE has not processed. Every missile that hits Dubai accelerates capital flight. Every arrest of a tourist accelerates it further. And the capital is not fleeing to London or Singapore. It is flowing to the country next door whose giga-projects have not been struck, whose airports have not closed, whose tourists have not been arrested, and whose $1.3 trillion Vision 2030 infrastructure is being built on a timeline that extends well beyond this war. Saudi Arabia signed a Strategic Mutual Defence Agreement with Pakistan in September 2025 that created a military depth Iran respected. Riyadh has absorbed far less direct targeting. NEOM, the Red Sea project, Diriyah Gate, the 2034 World Cup: all untouched. All funded. All under construction. Dubai intercepts the missiles. Dubai arrests the witnesses. Dubai demands the war escalate. And Saudi Arabia collects the capital, the perception of safety, and the long-term positioning that Dubai is burning through with every barrage and every prosecution. The air defenses work. The arrests do not. And the fertiliser trapped behind the permissioned strait at $683 per ton does not care about either. Full analysis: open.substack.com/pub/shanakaans…