Derek Cocker

Great to see this article out by @NovatisPatricas, highlighting that in East Africa, a One Health approach is crucial to addressing AMR 🧫💊🦠 doi.org/10.1016/j.lanm… @LSTMnews @sangerinstitute @LivUni @nfeasey1 #AMR

❗️Huge opportunity with our friends at the @FlemingCentre They're recruiting a Google DeepMind Academic Fellow to bring cutting-edge #AI to their efforts in addressing #AMR. 3-year post-doc | £54-64k | apply by 7 Sept 2025 👉 imperial.ac.uk/jobs/search-jo…

It does not have to be fancy to be effective! We have been studying patients with brain infections such as encephalitis and meningitis for decades. We have developed novel diagnostic tests, and worked on new treatments, but sometimes it’s the relatively simple things that can have the greatest impact. Our brilliant research Fellow @b5ingh has led an amazing programme over the past five years looking at the early management of brain infections, and trying to understand where it goes wrong, so that we could develop a package of interventions to improve things. And it’s actually worked! With hospital stakeholders, policy makers, and patient and public representatives, we co-designed a multifaceted clinical and laboratory intervention, informed by an evaluation of routine practice. The intervention, tailored for each setting, included a diagnostic and management algorithm, a lumbar puncture pack, a testing panel, and staff training. The study took place in hospitals across India, Malawi, and Brazil. We found the percentage of patients getting the correct diagnosis increased, they got on the right treatment quicker and there were improvements in functional outcome measures. Importantly, because we involved policy makers right from the start, and only used interventions which they said they could afford to maintain if they proved effective, these are sustainable interventions which are now being used every day. And what’s really exciting is that the intervention is already feeding into national practice guidelines and WHO meningitis and encephalitis initiatives, to be scaled up globally. Here’s a little video which tells you a bit more: youtube.com/watch?v=6d2-x_… And here is the paper just published in the Lancet for those who want to read more. thelancet.com/journals/lance…

Beautiful venue & fantastic workshops on intersectional research in Monkey Valley for the annual @wellcometrust @CAMO_Net1 research meeting 🇿🇦 🇬🇧 🇧🇷 🇮🇳 🇵🇰 🇺🇬 🇲🇼 🇹🇱 @chbonaconsa76 @SouthAfricanASP @Sanjeevsinghjpr @IDIMakerere @UCTHealthSci @RahAhmad @tjmidega @Uchea_C

🆕 By 2050, antimicrobial resistance (#AMR) could cause 1.91m direct deaths & 8.22m associated deaths globally. A Series in @LancetDigitalH explores the latest advancements & challenges in digital health approaches to address AMR: hubs.li/Q02YTdJG0 #WorldAMRAwarenessWeek

NEW Series paper: Using digital health technologies to optimise antimicrobial use globally. @TmRawson Read it here: buff.ly/3AIDwPq

Using digital health technologies to optimise antimicrobial use globally With @CAMO_Net1 and @HPRUamr As part of @LancetDigitalH series Addressing Antimicrobial Resistance with Digital Approaches sciencedirect.com/science/articl… @ImperialInfect @FlemingCentre

An innovative #norovirus vaccine #ClinicalTrial will open across the UK over the next 2 weeks. Despite being one of the most common and infectious causes of diarrhoea & vomiting, there aren't yet any licensed vaccines anywhere in the world 💉 Read more ➡️ nihr.ac.uk/news/uks-first…

In a joint collaboration supported by the Fleming Initiative, a Collection and call for papers has been launched by @NatureComms, @NatureMicrobiol, @NatureMedicine, @CommsMedicine, and @SciReports ⤵️ nature.com/immersive/anti…

Professor Alison Holmes has been appointed as the inaugural Director of the Fleming Initiative. Read the announcement from Professor Hugh Brady, President of @imperialcollege ⤵️ imperial.ac.uk/news/257174/pr…

Good to join others speaking at the launch of @bmj_latest Research Priorities for Future Shocks collection. Highlighted the importance of research to public health responses &how research can prepare us to rapidly respond to emerging public health threats @NIHRresearch @HealthFdn

UK Secondary Care colleagues - the ACDP Viral Haemorrhagic Fever (Contact HCID) guidance has been updated and is now available online, including an updated VHF risk assessment algorithm: gov.uk/government/pub…

Alongside this, genomic analysis from East Africa shows no barriers for ESBL producing E. coli transmission or independent antimicrobial resistance gene flow across ecological compartments. biorxiv.org/content/10.110… @NovatisPatricas @LSTMnews @LivUni @sangerinstitute

Great piece just published by DRUM consortia @NatureComms Focus on (a) emerging data showing that AMR is a One Health problem in LMICs (b) the role of WASH, and need for transdisciplinary and intersectoral collaboration rdcu.be/dWx5g @LSTMnews @LivUni @nfeasey1 #AMR

Check out our work in @BMJ_latest highlighting how innovations and research can be intergrated to protect healthcare and patient pathways from HCAIs and AMR bmj.com/cgi/content/fu… #AMR @HPRUamr @UKHSA

Innovative whole system approaches to integrate research and technologies in patient pathways can target antibiotic use, minimise healthcare associated infections, and adapt to novel pathogens, write @DerekCocker_ et al bmj.com/content/387/BM…

WHO, @UNEP, @FAO and @WOAH applaud countries for committing to ramp up global, regional and national efforts to address #AntimicrobialResistance through a One Health approach. This means recognizing the health of people, animals, plants and the wider environment, are closely linked and interdependent. Read more: bit.ly/4efypF1 UN Photo/Mark Garten

🏥Healthcare as a driver, reservoir and amplifier of antimicrobial resistance published in @NatureRevMicro rdcu.be/dONJM @DerekCocker_ @jesusrodman @RahAhmad @SupraChemina @CAMO_Net1 ⬇️Opportunities for interventions ⬇️

Healthcare as a driver, reservoir and amplifier of antimicrobial resistance: opportunities for interventions rdcu.be/dOVkK Holmes & co. examine how healthcare drives, harbors, and amplifies AMR, and explore solutions to mitigate healthcare-associated AMR.

Thanks go out to all co-authors @GBirgand @SupraChemina @jesusrodman @RahAhmad @kjambo Anna Levin @AHolmesID, alongside the support from colleagues across @CAMO_Net1 @MLW_Programme @HPRUamr

Check out our work in @NatureRevMicro highlighting: (i)how healthcare acts as a driver, reservoir and amplifier of AMR 🌍 🧫 🏥 & (ii) opportunities and innovations to both mitigate healthcare-associated AMR and promote healthcare resilience 💉 💊 rdcu.be/dONJM #AMR