Didonna Lab

A lab coordinator position is available at ECU Brody School of Medicine to manage the flow cytometry and cell imaging core facilities. If you have hands-on experience in these techniques and you are interested in the position apply here: ecu.peopleadmin.com/postings/89378

Multiple molecular mimics in Epstein Barr Nuclear Antigen-1, and the pathogenesis of multiple sclerosis pnas.org/doi/full/10.10…

Meet our 2026 Brody Brothers Endowment Research Grant recipients! These are primary investigators of deadly cancers, cellular metabolism, parasite-host dynamics and more. Thank you, Brody Family, for your _ongoing_ generous support of these researchers at @ECU.

Great teamwork for the traditional departmental door decoration contest that resulted in our first second place🎄

Some archaea—an ancient group of microorganisms—have an entirely novel genetic code, according to a new study in Science. Their genetic code reassigns a DNA “stop” signal to incorporate the rare amino acid pyrrolysine into their proteins. The findings expand our understanding of how alternative genetic codes evolve and hint at new molecular tools for biotechnology applications. scim.ag/49xnYx3

Thrilled to see our paper published in @FEBSJournal — We used a novel conditional knockout line to dissect the function of ataxin-1 in the B cell compartment @ECUBrodySOM febs.onlinelibrary.wiley.com/doi/10.1111/fe…

BREAKING NEWS: @Roche have announced their BTK inhibitor, #fenebrutinib, has achieved successful trial results in both relapsing-remitting & primary progressive #MultipleSclerosis. #MS [1/2] Read more: roche.com/investors/upda…

Thrilled for Rachael's first official persentation of her project on MS!

Excited to be part of the Neuroscience Symposium for the Eastern Carolina Chapter of the SfN. Here, John presenting his work on centaurin A1 in MS.

Thrilled to celebrate😀, Dr. Jill A. Hollenbach @jillahjillah recipient of the 2025 Bernard Amos Distinguished Scientist Award at #ASHI51! 🏅for her pioneering work in HLA & Immunogenetics. So proud to learn from the best. 🧬✨ #ASHI2025 #HLA #Immunogenetics

BREAKING NEWS The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”

It has been a great honor to visit the lab directed by Dr. Deborah Kronenberg-Versteeg at DZNE in Tübingen. Her amazing students conduct pioneering research on neurodegeneration and are truly passionate about science. I look forward to future collaborations!

DNA was isolated for the first time by Friedrich Miescher in Tübingen in 1869

Rainy Tübingen 🌧

I am glad to have contributed to this study describing the effects of SARS-CoV-2 infection on brain functioning @ECUBrodySOM @ECUResearch #tab2" target="_blank" rel="nofollow noopener">microbiologyresearch.org/content/journa…

A new #ScienceReview takes a look at the contribution of neuroinflammation during the course of a range of neurologic disorders, including #MultipleSclerosis, stroke, #AlzheimersDisease, and #ParkinsonsDisease. Read more: scim.ag/3GdAvt4

In @scisignal, researchers identify a molecular hub in neuronal dendrites that shapes the plasticity of synapses and find that the loss of these dendritic scaffolds might play a role in mouse models of Alzheimer's disease. scim.ag/4kawdAV

Thrilled to see the study funded by the Wooten Family Initiative finally published in The FASEB Journal. We show for the first time the involvement of CentA1 in autoimmune demyelination @FASEBorg @ECUBrodySOM @Bunner_Bean @ErzsikePhD faseb.onlinelibrary.wiley.com/doi/full/10.10…

Thrilled to talk about our imaging projects in the lab for the Microscopy Day @EastC

Great discussion group about healthy aging for the STEM@Starlight series @E