Dimitris Typas

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Dimitris Typas

Dimitris Typas

@DimitrisTypas

Senior Editor @NatureSMB. Views and opinions are personal.

Katılım Mayıs 2012
341 Takip Edilen490 Takipçiler
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Jakob Nilsson
Jakob Nilsson@NilssonLabCph·
Happy to see our work on defining a dependency map of short linear motifs out. We use base editing screens to install more than 80000 mutations into SLiMs in more than 4000 proteins to determine their contribution to cell fitness. nature.com/articles/s4159…
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Cris Mayor-Ruiz
Cris Mayor-Ruiz@CrisMayorRuiz·
🔥 Chem(bio) friends, this one is big!! IRB Barcelona is opening a Group Leader position in Chemical Biology! 💜 If your research plan and vision are at the interface of synthetic chemistry, chemical biology, and biomedicine, please check the call! 👉recruitment.irbbarcelona.org/jobs/7334978-g…
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Dimitris Typas
Dimitris Typas@DimitrisTypas·
A well-worth-your-time Comment by Dr. Edith Heard, of @TheCrick, and Dr. Gitte Neubauer, one of the founders of Cellzome, now at GSK, is out @NatureSMB . They provide valuable insight into what makes a successful partnership between academia and industry. nature.com/articles/s4159…
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Dimitris Typas
Dimitris Typas@DimitrisTypas·
Tempted to add (more) METAL gifs, but we @NatureSMB are indeed glad to feature METALoci and the conceptual advance imparted by the study in our pages.
Irene Mota@IreneMota

How is sex determined? How is it encoded in the #3Dgenome? Happy to share my PhD work. Sex-determining 3D regulatory hubs identified w METALoci, a new genome spatial auto-correlation approach With @jrotwitguez Capel Lab @mamartirenom @Dariloops Thread 👇biorxiv.org/cgi/content/sh…

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Dimitris Typas
Dimitris Typas@DimitrisTypas·
Late to the party, but I wanted to highlight a recent @NatureSMB paper by the Hajkova and Vaquerizas labs, which notably advances our understanding of how chromatin organisation regulates gametogenesis. Very enjoyable and insightful work! nature.com/articles/s4159…
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Dimitris Typas
Dimitris Typas@DimitrisTypas·
Our September @NatureSMB issue is out! nature.com/articles/s4159… We feature very interesting papers on ubiquitylation and degradation. Really excited to continue to serve the proteostasis and PTMs communities and publish conceptually insightful work.
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NatureStructMolBiol
NatureStructMolBiol@NatureSMB·
New online! Q&A with Yael David and Charles Rice on using chromatin biology to understand hepatitis bit.ly/4nYQqwI
NatureStructMolBiol tweet media
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BökeLab
BökeLab@LabBoke·
Proud to share what we hope will be a reference study on human oocyte proteostasis. Young-donor eggs show globally reduced organelle activity vs. somatic cells, with an even steeper drop as they mature. 👇 for @zaffagg3 's detailed explanation embopress.org/doi/full/10.10…
Gabriele Zaffagnini@zaffagg3

📣 Paper alert!! Excited to share the 2nd research paper from my time in the @LabBoke at @CRGenomica, out today in the @embojournal! We asked: "how do human oocytes regulate proteostatic organelles under physiological conditions?" We collaborated with @DexeusMujer and employed #healthy human oocytes freshly donated for heterologous IVF 1/

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Dimitris Typas
Dimitris Typas@DimitrisTypas·
Scientists travel to work. Some continue to travel during their career, some set roots to an adopted country, some return. @NatureSMB will publish 5 pieces on those that returned. The first discusses Dr. Gomes Dias' return to Brazil. Touching+inspiring. nature.com/articles/s4159…
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Dimitris Typas
Dimitris Typas@DimitrisTypas·
Out @NatureSMB a Review on origin licensing with the most comprehensive (and coolest!) movies on how pre-RC assembly works. Decades of structural and biochemical work are beautifully illustrated. Kudos to @janetiwasa, John Diffley and Bruce Stillman. nature.com/articles/s4159…
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Dimitris Typas
Dimitris Typas@DimitrisTypas·
On the way to #cshlubiq; the speakers and posters sound top-notch. If you have any questions about @NatureSMB or just want to chat science, please feel free to say hi.
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Dimitris Typas
Dimitris Typas@DimitrisTypas·
A bit late to promote this excellent work reporting the development of BRISC molecular glues (BLUEs) nature.com/articles/s4159…. This paper is the first in a series of insightful ubiquitylation-related manuscripts with disease-related relevance @NatureSMB will publish
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Roger Greenberg
Roger Greenberg@RogerRogergr·
Please see our discovery of first-in-class BRISC deubiquitylating enzyme inhibitors rdcu.be/edRwF. A great journey with Elton Zeqiraj, Francesca Chandler, Joe Salvino. High-throughput screens, cryo-EM structure and ontarget activity to reduce inflammatory signals.
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Keşfet

@TheCrick @NatureSMB @Anders_S_Hansen @MITdeptofBE @LabBoke @RiceLaboratory @MSKCancerCenter @zaffagg3