Divya Krishna Kumar

(1/8) Still wondering how low complexity intrinsically disordered regions (IDRs) guide transcription factors (TFs) to bind in genomes? Previous studies on sequence grammars; our new @MolCell paper takes the next step: de novo design of functional TF IDRs! cell.com/molecular-cell…

Exciting work! @MindelVladimir @SagieBr

New 📄 by @tamar_jana + @SagieBr We introduce MPBA, a novel method allowing parallel measurement of TF binding to thousands of designed DNA sequences within cells. We use it to answer a fundamental question - how prevalent is TF binding cooperativity. 1/9 tinyurl.com/2s4bbu65

I am super excited to share our new paper in @NAR_Open about all the complex ways of how IDRs regulate the binding patterns of Gln3!🥳🎉 Thank you everyone for such an amazing work together, especially @Divya_KKumar @FJonas15 @BarkaiLab

🔥New paper out in @NAR_Open! 🔥 Thrilled to have taken another step towards understanding the role of disordered regions in eukaryotic transcription factor binding specificity Enjoyed working with the very best @bhurieva @FJonas15 @NaamaBarkai

Check out our new paper: “Intrinsically disordered regions of the Msn2 transcription factor encode multiple functions using interwoven sequence grammars” published @NAR_Open. The work of @MindelVladimir and @SagieBr. academic.oup.com/nar/advance-ar…

Amazing work by @OffirLupo @BarkaiLab now online in @CellSystemsCP 🔥

Read the newest chapter of the histone timer⏲️arc in our @NAR_Open paper investigating 🧐 the role of different histone chaperones and remodelers using the . Special thanks to Gilad, it was again great working with you👨‍🔬 and the other members of the @BarkaiLab👩‍👧‍👦. (🧵)

New @NAR paper by @FJonas15 & Gilad defining main activities of histone chaperones & chromatin remodelers in nucleosome exchange 🐣 Do they mainly incorporate nucleosomes displaced by transcription? Increase exchange in promoters to enable TF binding? doi.org/10.1093/nar/gk…

@chongloi_g @FJonas15 @BarkaiNaama Thank you Grace!

@Divya_KKumar @FJonas15 @BarkaiNaama Congratulations Divya!!!!

🤩Our paper is online! We elucidate the role of IDR rich DBD external regions in directing promoter selection. I had great fun, and learned a great deal working with the best team @FJonas15 and @BarkaiNaama

🥳🎉We are delighted to share our new paper that deciphers the complementary strategies by DNA binding domains (DBDs) and IDRs in directing transcription factor (TF) target specificity. 🎉🥳 cell.com/molecular-cell… @Divya_KKumar @FJonas15 @BarkaiNaama

Online Now: Complementary strategies for directing in vivo transcription factor binding through DNA binding domains and intrinsically disordered regions dlvr.it/Sn9dXZ

🤩Our paper is online! We elucidate the role of IDR rich DBD external regions in directing promoter selection. I had great fun, and learned a great deal working with the best team @FJonas15 and @BarkaiNaama

Proud to present our 🎉new paper🎉deciphering the IIDR grammar of transcription factor target specificity: doi.org/10.1093/nar/gk…. Special shout out to my fellow code breakers 🕵️ @BennyKrupkin and MiriCarmi and the rest of the @BarkaiLab - follow 🧵 for highlights

Excited to share our newest preprint by @TamarGera @FJonas15 & Roye More: Evolution of binding preferences among whole-genome duplicated transcription factors biorxiv.org/content/10.110… Ever wondered how the transcriptional network evolves? Read more to find out! (1/7)

Our new paper, led by Gilad Yaakov and @FJonas15 just came out! @NatureBiotech ⏱We used molecular timers to measure histone exchange genome-wide. 1/5 nature.com/articles/s4158…

Thanks to support from @CapgeminiIndia @HFSP we have several positions to work on developing new methods/tests and ask challenging questions in infectious diseases. Please RT ! ! nanobiology.nanobiophotonics.org/home/open-posi…

We, as citizens of India, are 'Independent' every day but many of us don't understand it's true meaning. Unfortunately for many it's 'just' a holiday or a person's birthday to remember once in 365 days.

Excited to share my latest work together with @tamar_jana published today @MolecularCell. We focused on how transcription factors that bind similar motifs in-vitro localize to distinct promoter sets in-vivo. @BarkaiLab @WeizmannScience (1/7) cell.com/molecular-cell…