Dr EJ

People who have razor-sharp minds in their 80s and 90s – known as “SuperAgers” – produce twice the number of young neurons as cognitively healthy adults and 2.5 times as many as people with Alzheimer’s disease, a new study found. cnn.it/4rFbYjk

New figures reveal how many healthy years men and women in every NI council area can expect belfasttelegraph.co.uk/news/new-figur… belfasttelegraph.co.uk/news/new-figur…

Small amounts of exercise are associated with a longer life. Walking is particularly effective.

New nationwide cohort study links social determinants of health and Life’s Essential 8 metrics with cardiovascular morbidity and mortality, highlighting the impact of both social and behavioral factors on heart health. 🔗 ow.ly/OKpH50XLCQC #HeartHealth #LifeEssentials8

"Higher intake of high-fat cheese and high-fat cream was associated with a lower risk of all-cause dementia." Results of a 25-year prospective study of ~27,000 participants. The purported benefit was not linked to APOE4 carriers or low-fat cheese intake neurology.org/doi/full/10.12…

Effects of Greek Yogurt Supplementation & Exercise on Markers of Bone Turnover & Inflammation in Older Adult Exercisers mdpi.com/2072-6643/17/2…

👨 Today we're launching our landmark Men's Health Strategy. This action plan will tackle the specific health challenges faced by men and boys. Men's health has been overlooked for too long. We're changing that by meeting men where they are. More: gov.uk/government/new…

Nutrition Society - Free University Group Membership for undergraduates - Act now! Open to all undergraduate nutrition students. To secure your place, ask an academic at your university to complete the quick registration form on your institution’s behalf. nutritionsociety.org/register-your-…

Where vitamins and minerals are stored in the body Vitamins and minerals use different storage strategies. Some are stockpiled in organs and tissues, while others are used immediately and must be replenished often. Storage pattern explains why some deficiencies appear quickly and why a few nutrients can accumulate to toxic levels if overconsumed. 1️⃣ Water-soluble vitamins (B-complex, vitamin C) Mostly circulate in blood and are not stored in large amounts. Excess is lost in urine, so steady intake matters. Vitamin B12 is the notable exception and is stored in the liver for years. 🟢 Example: a few weeks with little vitamin C can cause fatigue and gum irritation, while low B12 may not show up for months because liver stores buffer intake. 🟢 Example: intense sweating or diuretics can raise B-vitamin needs since these dissolve and leave with fluids. 2️⃣ Fat-soluble vitamins (A, D, E, K) Absorbed with dietary fat and stored in liver, adipose tissue, and to a lesser extent skin. Deficiency develops slowly, and excess intake can accumulate. 🟢 Example: vitamin D stored in liver and fat can help maintain status through winter when sunlight is low. 🟢 Example: chronic high vitamin A intake from supplements can build up in the liver and cause headaches or skin peeling. 3️⃣ Major minerals (calcium, magnesium, phosphorus, potassium, sodium, chloride, sulfur) Stored mainly in bone, muscle, and extracellular fluids. They maintain structure and electrical balance. 🟢 Example: about 99 percent of calcium is stored in bone; low dietary calcium draws from bone reserves over time, weakening bone density. 🟢 Example: magnesium is stored in bone and muscle; heavy sweating or stress can deplete it and trigger muscle cramps or irregular heartbeat. 🟢 Example: sodium and chloride are held in extracellular fluids; high salt intake increases extracellular volume and can raise blood pressure in salt-sensitive people. 4️⃣ Trace minerals (iron, zinc, copper, selenium, iodine, manganese, chromium, molybdenum, fluoride) Required in small amounts with specific storage sites. 🟢 Example: iron is stored as ferritin in liver, spleen, and bone marrow; low ferritin reduces red blood cell production and causes fatigue. 🟢 Example: iodine concentrates in the thyroid gland to make thyroid hormones; low iodine intake slows metabolism and can enlarge the thyroid. 🟢 Example: zinc is distributed in skin, pancreas, and brain; low zinc impairs wound healing and blunts taste and smell. 5️⃣ Choline and other water-soluble nutrients Choline is stored in the liver and incorporated into phospholipids and acetylcholine. 🟢 Example: inadequate choline raises risk for fatty liver and can affect memory because the body cannot synthesize enough to cover needs in many people. Water-soluble vitamins are used quickly and need regular intake. Fat-soluble vitamins and many minerals can be stored for longer periods, which delays deficiency but increases the risk of buildup with excessive supplementation. The liver, bone, muscle, fat, and thyroid serve as the body’s nutrient vaults, releasing or storing what the brain and tissues need in real time.

15th International Conference on One Carbon Metabolism, B Vitamins and Homocysteine. June 24-27, 2025, Nancy, France. For the past 3 decades, this multidisciplinary conference has covered the most advanced research of the topic in the fields of experimental and clinical medicine, biochemistry, metabolism, nutrition and public health. The program will be organized in sessions chaired around lectures given by eminent specialists in the subject and will devote particular attention to providing opportunities for young scientists and postgraduate students to present their research through invited conferences, short or flash oral communications and posters. The Friday round table will allow open discussions between experts and participants on the diagnosis and treatment of B vitamin deficiencies. Invited and selected papers from the conference will be published in the journal "Biochimie". Congress website: intconf1cmmvitb.event.univ-lorraine.fr/?lang=en

Vitamin D supplementation may reduce respiratory infections in children, mortality in older adults, and diabetes progression in prediabetics, with inconclusive evidence for other benefits. ja.ma/4n0yEZh

Bridging Research & Practice: Women’s Health and Wellbeing Webinar Recording 📅 29 May 2025 | 🎥 Recording & slides now available: tcd.ie/tcaid/research… Thank you to everyone who registered and joined us for this important discussion on the unique health and wellbeing needs of women with intellectual disabilities. We recognise that not everyone who registered could attend on the day — but that shouldn’t mean missing out on the insights shared. This webinar offered a vital platform to highlight both the unique challenges and real opportunities to improve care for women with intellectual disabilities. Topics included bone health, menopause, obesity and physical activity, mental health, loneliness, and the broader social determinants that shape health outcomes for women with intellectual disabilities. We’re grateful to all our speakers, contributors, and attendees who made the session so engaging. We’ve been heartened by the positive feedback — here’s what some participants had to say: 🗨️ “Really informative and relevant presentations — so encouraging to see this research being undertaken.” 🗨️ “Best 2 hours I’ve spent this week. Really insightful and educational.” 🗨️ “Thank you — excellent presentations, a great seminar.” 🗨️ “Fantastic webinar. So insightful, and such a huge amount of work displayed.” Watch the full session and access presentation slides here: 👉 tcd.ie/tcaid/research…

“The lack of clear-cut evidence for vitamin D supplementation as a staple of chemoprevention means that clinical guidelines must be nuanced.” This Editorial discusses the Endocrine Society's 2024 vitamin D supplementation guidelines and the accompanying clinical synopsis in JAMA. ja.ma/4mHzzxx

This podcast episode to bookmark & share,🔊 "Irish Medical Lives" hosted by Dr Chris Luke with guest,our own, Professor J.B. Walsh @jbwalsh @stjamesdublin #MISA @tcddublin ; his inspirational life story shared, hosted by Dr Chris Luke.😎 #Cork #DurhamUK #Ireland #GeriatricMedicine #HealthyAgeing #BoneHealth #SJHCommunity @irishgerontsoc @RoseAnnekenny1 @2013_Sylvius @DiarmuidOShea @RCPI_news @roinnslainte @CarrollJennifer @CcoHse @TrinityMed1 @TCDGerontology Link🔗 open.spotify.com/episode/1hPCqQ…

@atu_ie @atuhealthysligo @atusligo_ie @healsrc @ATU_ResearchIE @ThomasConnolly_ @pnolan99 @EamonJL @Aine_Roddy @KonradMulrennan @padraigmcg @richeal101 @Sureshpillai @SligoStats @haughey_aidan @coughlks

Pope Francis died on Easter Monday, April 21, 2025, at the age of 88 at his residence in the Vatican's Casa Santa Marta.

At 9:45 AM on Easter Monday, Cardinal Kevin Farrell, Camerlengo of the Apostolic Chamber, spoke these words at the Casa Santa Marta: "Dearest brothers and sisters, with deep sorrow I must announce the death of our Holy Father Francis. At 7:35 this morning, the Bishop of Rome, Francis, returned to the house of the Father. His entire life was dedicated to the service of the Lord and of His Church. He taught us to live the values of the Gospel with fidelity, courage, and universal love, especially in favor of the poorest and most marginalized. With immense gratitude for his example as a true disciple of the Lord Jesus, we commend the soul of Pope Francis to the infinite merciful love of the One and Triune God." vaticannews.va/en/pope/news/2…

It is harder for our bodies to absorb key nutrients from plant-based foods, so some vegans may be short on essential amino acids for healthy muscles and bones despite eating plenty of protein #Echobox=1745113400" target="_blank" rel="nofollow noopener">newscientist.com/article/247701…

Check out some of recent my comments on weight loss drugs featured in the British Medical Journal (impact factor >90!) #impact #research @atu_ie @atusligo_ie bmj.com/content/388/bm…