Ragada El-Damanawi

We are running a phase III, randomised control trial investigating the implementation of Metformin therapy to ease decline of kidney function in PKD If you are interested in participating in our trial as a research site, please contact us at IMPEDE.PKD@uea.ac.uk @NorwichCTU

Excited to be mentioned in the PKD Charity Newsletter #impedePKD

THREAD 🧵 There are three things in the photo that virtually nobody else sees but me.

🇺🇳 The United Nations has voted Francesca Albanese, the UN special rapporteur on the Occupied Palestinian territories as the Person of the Year..! Francesca has fought relentlessly for an end to the worst genocide in our modern history.

The more I reflect on what happened in Amsterdam the stranger it seems. A racist team who have a reputation for hate speech come to Amsterdam during a genocide and engage in acts of racism and violence against the local population. They are accompanied by Mossad agents. All this happens under the increased success of Islamophobic Geert Wilders and the PVV. The media, not just in the Netherlands but in Europe and North America publish what looks like an Israeli press release using incendiary language about pogroms and Kristelnacht. Politicians around the world immediately and uncritically embraced this rhetoric and say nothing of pro-genocidal chants. They media mislabel on the ground journalism by Dutch photographer @iAnnetnl to minimise Israeli violence. They ignore evidence from other Dutch journalists like @OmeBender. Channels like Sky News even re-edit packages to maximise the narrative of antisemitism and minimise examples of anti-Arab racism. Dutch parliamentarians then wield propaganda by the Israeli diaspora affairs as if it constitutes evidence. Many media outlets still haven't corrected the record about what happened, from the BBC to WSJ and Sky. It's disturbing and sinister, and shouldn't be allowed to slide.

The facial expressions are priceless ♥️ “I told you”

🎙️That’s what we had on the table for @FreelyFiltered recorded #nephjc #kidneywk 🤔Can you guess what the were the choices were? @sophia_kidney @kidney_boy @hswapnil @jordy_bc @captainchloride @Jwaitz

This is a worry. How can we make clinical academic training more attractive? @NIHRresearch

Wondering what RaDaR is? We’re the National Registry of Rare Kidney Diseases 🧬 - a powerful source of real-world data that can help improve understanding of rare kidney conditions & provide info for research & clinical trials. 📊🔬 Find out more ➡️ rarerenal.org

New in NEJM Evidence! Original Article by @_jeffreyha et al.: Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors in Kidney Disease eviden.cc/3z2CLzM @Badves @MinJun____ @hswapnil @DrDanMO @SuetoniaPalmer @DavidCWheeler2 @VladoPerkovic @georgeinstitute @UNSWMedicine

BREAKING : The UN accuses Israel of committing EXTERMINATION in Gaza. EXTERMINATION. Repeat it. Spread it. Let the world know. “Israel is responsible for extermination, murder, using starvation as a method of war..” —The UN Human Rights Council

#UCLTransplant24 booking is live - with more interactive sessions and several new topics. Great value. All welcome to share and learn. ucl.ac.uk/nephrology/ren…. @RenalUCL @ISNkidneycare @RenalSpRClub @Kidney_Research

eGFR slope analyses from SMART-C @brendonneuen - my favourite figure from this meta-analysis presented on the day FLOW caused waves at #ERA2024 - it looks like GLP1-RA must be upgraded to standard of care for albuminuric DKD with the other pillars 😃

Wow Minimal change disease RIP Roughly half (higher in kids?) = anti nephrin podocytopathy Multicentre study validating @AstridWeins et al findings at #ERA24 in @NEJM nejm.org/doi/full/10.10…

#SELECT Kidney Outcomes now out in @NatureMedicine with #ERA24! Sema 2.4mg ow ✅ 22% ⬇️ 5-point kidney composite outcome, driven by UACR reduction ✅ 0.75mL/min slowing in eGFR decline Kidney protection evident even in lower risk pts without DM or CKD! nature.com/articles/s4159…

#ERA24 Clinical pearls from CKJ @CKJsocial by speaker @KateIsabelle24 post by @G_ErtanDemirtas, social media team 1. First pearls, 🔎what about membranous nephropathy? The place of cyclical therapy for the treatment of membranous nephropathy in the era of rituximab doi.org/10.1093/ckj/sf… AND Anti-CD20 should be the first-line treatment in high-risk membranous nephropathy doi.org/10.1093/ckj/sf…

This slide by @SWadhwaniMD summarises it beautifully. The paradigm is shifting and time to slow down “Time to Cliff” IgA express. #ERA24

The third presentation in #ERA24 LBCTI is 🥁Randomized Phase 2 Trial of Felzartamab in Humoral Transplant Rejection ✍️By Katharina A. Mayer 📍Late antibody-mediated kidney transplant rejection (AMR) is the leading cause of transplant loss 📍Long-term outcomes after AMR diagnosis remain poor 📍No therapeutic strategies have demonstrated efficacy

Details of the SMART-C analysis of the effects of SGLT2i by baseline GLP-1RA are in press in The Lancet Diabetes & Endocrinology Full slide deck now available for download at SMART-C.net/resources #ERA24 @ERAkidney