Ethan Rowin

58 posts

Ethan Rowin

Ethan Rowin

@EthanRowin

Co-Director Hypertrophic Cardiomyopathy Center, Lahey Hospital and Medical Center; Own tweets not reflective of employer or industry; LFGM

Katılım Kasım 2022
94 Takip Edilen155 Takipçiler
Ethan Rowin retweetledi
Gautam Gadey
Gautam Gadey@GGadey·
Lahey Hospital and Medical Center is currently looking to hire a structural fellow for the 2026-2027 academic year. Join a collegial and busy team with large volumes that is always coming up with creative solutions! If you would like to apply, please message me.
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Amro Aglan
Amro Aglan@AmroAglanMD·
Honored to join @JAHA_AHA Early Career Editorial Board starting January 2026. Grateful for the opportunity to learn the editorial process and contribute to high-quality cardiovascular and arrhythmia research. #CardioTwitter #EPeeps
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Ahmad Masri
Ahmad Masri@MasriAhmadMD·
We presented long-term data from #FOREST #HCM on the incidence and impact of atrial fibrillation in patients treated with aficamten in the Cardiomyopathy LBCT session Led by @EthanRowin #ESC2025 #CardioTwitter
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Ethan Rowin
Ethan Rowin@EthanRowin·
@MasriAhmadMD Agree re trade offs and also surprised with a 6month duration btwn echos for pts with EF55-60%, especially since in MAVA-LTE ~6% of patients had either EF<50 or acute HF btwn wks 48 and 156. So potential for more adverse outcomes with this change. Will see with time.
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Ahmad Masri
Ahmad Masri@MasriAhmadMD·
New mavacamten FDA label update Most relevant parts: 1) Initiation strategy remains the same 2) Maintenance phase echo requirement dropped to once every 6 months instead of once every 3 months This will help with patient and staff burden during the maintenance phase. I would have considered LVEF>60% rather than 55% given the variability and the trade-offs. We plan to continue to study the real-world use of mavacamten and safety outcomes with these changes. Such changes will limit the clinicians' ability to get more frequent echos if concerned about a particular patient since most payers will follow the REMS and decline additional echos. Initiation phase remains rigid without flexibility in echo scheduling, and the downtitration requirements did not change either. Overall really positive changes that our patients will like but there will be trade offs. #CardioTwitter
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Ahmed Sayed
Ahmed Sayed@ASayedMD·
How have HCM mortality rates changed before and after COVID ❓ 1⃣ Prior to COVID, mortality rates declined by ~ half📉 2⃣ After COVID, mortality rates increased by ~30%, partially undoing some of the prior reductions in HCM mortality.📈 Open access📜: ahajournals.org/doi/full/10.11…
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Amro Aglan
Amro Aglan@AmroAglanMD·
Really valuable and novel data presented by Dr. @EthanRowin — Does LV apical aneurysm size matter for SCD risk in #HCM? 🏥 Multicenter data says yes! #ACC25 #CardioTwitter
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Saad Ur Rahman
Saad Ur Rahman@SaadUrRahman55·
“Excited to share our latest editorial published in @CircAHA - Our study highlights T1 mapping as a novel marker for heart failure progression in hypertrophic cardiomyopathy (HCM). @EthanRowin @JAHA_AHA @AHAScience
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Ahmad Masri
Ahmad Masri@MasriAhmadMD·
Mavacamten in #nonobstructive #HCM design and baseline characteristics paper is out (ODYSSEY trial) ! Biggest unmet need in HCM is nonobstructive HCM. We look forward to the results. Impressive baseline characteristics with significant burden of disease Sample size caught my eye. The study planned to enroll 420 patients, yet the paper shows 580 patients were randomized. The paper does not provide rationale (if I missed it please point it out). This makes ODYSSEY the largest study conducted in #HCM Other interesting aspects: unclear how titration is being approached, and this is the first time we see a global study of mavacamten with 1 mg being used. Results expected this year jacc.org/doi/epdf/10.10…
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Ethan Rowin
Ethan Rowin@EthanRowin·
@MasriAhmadMD Congrats! Impressive results. The AFib data is remarkably low and very reassuring. Do you have publicly available info on timing of the few EF drops?
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Ahmad Masri
Ahmad Masri@MasriAhmadMD·
While these SRT eligibility cut offs are arbitrary - patients do ask the question: what are the chances that this medication can work and allow me to avoid surgery/procedure? These data can help mange such a conversation once aficamten becomes commercially available
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Ahmad Masri
Ahmad Masri@MasriAhmadMD·
We presented new data from #FOREST #HCM which is an ongoing 5 year long term extension trial of aficamten. This analysis is restricted to 280 pts with #oHCM Primary endpoint at week 12 Titration period in the first 6 weeks given its half life Follow along #CardioTwitter
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