Franc

Someone asked about tricks for meeting eminent people. I said the best plan is just to do really good work. Then you'll tend to meet them organically. In the worst case you'll see one whenever you look in the mirror.

Now that everyone is an expert on curing pancreatic cancer in mice, not rats - I want to add some context that goes beyond the headline. You will want to read this. Cancer is cured in mice all the time. Thousands of times. ~90% of those “cures” fail in humans. Why? Because mice are: Genetically simpler. Treated earlier. Short-lived. Not humans. Mice are a filter - not a finish line. Yes, this study matters. It comes from the Spanish National Cancer Research Centre. Yes, it’s pancreatic cancer - one of the deadliest there is. Yes, full tumor regression is impressive. But here’s what it actually means: “This approach is now good enough to risk years, trials, and millions of euros on.” Not: “Cancer is solved.” What happens next? More animal work. Toxicology. Phase I (safety). Phase II (maybe works). Phase III (beats standard care?). Maybe 8-10 years if everything goes right. The real damage isn’t failed drugs. It’s failed expectations. Every “cured cancer in mice” headline trains the public to believe: Cures are being hidden. Progress should be fast. Scientists are lying when reality hits. That’s how trust erodes. Bottom line: This is how real cancer progress looks. Messy. Slow. Risky. Incremental. Not miracles. Not conspiracies. Just science - doing the hard work.

@slotcoffee Slotcoffee

Prize just went up to $4,000. Grok says word has not been chosen yet.

It wasn’t my best year and not quite what I expected, but I still made it through. I’m deeply grateful for the gift of friends and family. Next year will definitely be better.

@drip_haus Gm

gm, you have 72hrs to say it back.

I noticed a lag between my Solstice dashboard flares and that of Exponent. I decided to sell YT-USX a few days ago and my Solstice dashboard flares hasn't been updated till now. Why the discrepancy @solsticefi ?

@Crypto_Zh0u @solsticefi Interested

BREAKING SOLSTICE ALPHA: As one of the more active creators on @solsticefi, I'm given access to share the $SLX pre-sale community priority list to my community only 👀 Currently the pre-sale committed amount already surpasses $69m ➣ I can share the link but via DM only Please make sure you follow me & comment "Interested in $SLX" below 👇🏻

@ElinaMia34 Congratulations 🎉🎉

@cascade_xyz Bring it on.

The first 24/7 neo-brokerage. Trade perpetual markets for crypto, equities, and private assets. Move USD in and out, all from one unified account. 48 hours to secure an early invite. cascade.xyz/join

@arjunnchand Massive congratulations to you guys

we’ve raised $29M series A extension, funded by Multicoin and CoinFund! huge thanks to everyone who chooses to back us for the long term! crypto is the technology of this era. the world is coming onchain. and LI.F​I is building the universal market for all digital assets. still day 1 🤝

Hi everyone, My name is Ufuk. My life changed in an instant after a diving accident that left me 97 percent disabled and paralyzed from the neck down. I cannot use my hands, and I am still in the hospital, fighting through constant infections, pain, and long stays in intensive care. Over the years, the weight of this journey has grown heavier, and even my mother, my biggest source of support, can no longer carry this burden alone. Several treatments and surgeries that I urgently need are still out of reach, and the emotional and physical challenges have become overwhelming. Still, I am fighting, holding on, and hoping for a chance to receive better care. This NFT was created to support my medical needs. Every contribution brings real hope and helps me continue this difficult journey. For “One Mint, One Hope,” I am sharing the @opensea mint link below. 👇 Thank you all. 🫶 opensea.io/collection/lim…

I didn't know that the Fusaka upgrade would make transactions cheap on Ethereum, wow. The chain is healing

@LitecoinVM Just when I thought that innovations are dead 🤧

LitVM supercharges $LTC with a wide range of yield opportunities. You'll soon be able to put your Litecoin to work and grow your stack 🔥 Find out more in the article linked in the post below.

@kaledora Congratulations 🎉🎉

Today, I'm thrilled to announce that we've raised an additional $24 million in new capital, including a $20 million Series A co-led by General Catalyst and Jump Crypto, along with Wintermute Ventures, Coinbase Ventures, Crucible Capital, and an incredible set of angels. They will be key to actualizing our vision: democratizing access to the highest quality and most liquid global asset markets in the world. We started Ostium with the vision of upending the legacy CFD market, an idea that Marco and I first conceptualized trading on offshore brokers in a hacker house. These platforms happily let users like us take risky positions, but when those same positions moved against them, they’d swiftly exercise discretion over pricing, liquidations, and withdrawals. It took sending countless emails pushing brokers to honor their own terms to realize the system was broken. From day one, our goal has been to fuse two core values into a single product: (1) the transparency and self-custody of crypto, and (2) the fair pricing and deep liquidity of traditional markets. Those two north stars have shaped every architectural decision we’ve made since. Scaling Liquidity To scale that model without compromise, Ostium is expanding its liquidity partnerships. The protocol will now be able to support dramatic increases in liquidity, open interest, and asset coverage, allowing us to expand into the most liquid markets in the world. This growth is supported by a core set of liquidity partners able to hedge flows across a diverse range of traditional assets while integrating directly with crypto rails. Today, Ostium’s main hedging partner services the protocol by managing the bulk of these flows, hedging exposures when they exceed certain thresholds, and ensuring open interest doesn’t skew too heavily in a particular direction. That hedging capacity will be expanded materially with new liquidity integrations. There's also a new, comprehensive dashboard detailing the live and historical hedging positions on the protocol, allowing anyone to track the residual exposure OLP is taking on at any time. Check it out at ostiscan(.)xyz. In the coming months, the Ostium protocol will evolve from a single-quote RFQ system into a competitive quoting environment, wherein makers will compete directly at the protocol level to quote and hedge large orders. Their participation will be gated and their economic alignment with the protocol ensured via an inbuilt native staking mechanism and slashing system. Why We Chose This Architecture Our architectural choices follow directly from this vision. Building a fully onchain execution engine inherently delivers transparency and self-custody. But crypto rails today often make fair pricing and deep liquidity harder, especially for longer-tail traditional assets. The result is that while many traders may think they are trading a multi-trillion dollar market like the gold market, they wind up in fact betting on an illiquid derivative thereof, subject to the often unreliable liquidity dynamics of the crypto markets. As a result, we opted to build a single-quote RFQ model, not an orderbook exchange. Ostium quotes directly from a specialized oracle, enabling the protocol to price assets at the underlying market's price (or very close to it) and offer the closest thing onchain to the execution depth that a trader would get in the real markets. Points Program Updates In line with this expansion, two changes to the points program to double down on our core focus: 1. CFD trader onboarding boost If you’re a traditional CFD trader and want to Break Up With Your Broker to trade onchain, you’ll be eligible to receive a 2x boost on all points earned for the first 30 days from signup with Ostium. If this is you (or any of your friends), please fill out the form on Ostium’s landing page and forward broker affiliation to breakup@ostium.io. (Note: not available in U.S. / for U.S. traders) 2. TradFi boost From now on, we will be increasing points program scores on all traditional assets - stocks, indices, FX, & commodities. This is the first and only trading venue in DeFi today with over 95% of open interest in traditional markets, and we will be doubling down on our core focus. Finally: if you want to work with a brilliant team, we're hiring the very best across a variety of positions. We look for exceptional and spiky people. If this is you, join us. (https://jobs.ashbyhq(.)com/ostium)

@OxNipsey Animoca

Which of these VCs are walking red flags especially with trash TGE execution? Yzi labs Hack VC Animoca labs Delphi Ventures Pantera Capital Mirana Venturea Hashkey Capital

Again why will you want to build a smart contract on Bitcoin chain when Satoshi didn't build it for such?

Who is the dev withholding this new meta? Please launch it, CT is at its breaking point

Everybody is just catching cruise. The market is boring, ZEC is retracing, monad is dumping, Zayn is quoting laws, Infinex is being fudded.

@Crypto_Zh0u @solsticefi Thanks for bringing this tool to my timeline 🙂

Liquidity Pools of @solsticefi: 30th Nov: ➣Exponent: USX: $16.9M eUSX: $12.6M ➣Kamino: eUSX Supply: $8.3M USX Supply: $12.4M Borrowed: $11.4M ➣Orca: USDC/USX: $12.7M USX/eUSX: $5.1M ➣Raydium: USX/USDC: $6.3M USX/eUSX: $4.2M Total LP: $78.5M

@Crypto_Zh0u @katexbt Yeah. I don't even think that Jumper will TGE

@katexbt Tbh jumper has many partnerships or rewards that benefit those with certain levels

Duration of the longest points programs still active: 1. MarginFi - 919 days 2. Photon - 647 days 3. RainFi - 628 days 4. Ambient DEX - 1212 days 5. OpenSea - 1819 days 6. DFlow - 585 days 7. The Vault - 611 days 8. FantasyTop - 851 days 9. Jumper - 693 days It's over.