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Thrilled to share our new paper in @NatureHumBehav!
nature.com/articles/s4156…
We show that combining biological 🧬 and psychosocial 📋 data offers a much stronger, more reliable path to predicting pain and diagnosis. 🧵
English
Matt Fillingim
52 posts
Matt Fillingim
@FillingimMatt
PhD neuroscientist | Biomedical data scientist Pain, biomarkers, and large-scale human data
Montréal, Québec Katılım Aralık 2011
237 Takip Edilen123 Takipçiler
Matt Fillingim retweetledi
New paper w/ @_LeeJaeJoong_ in Nat Neurosci!🧠 We developed personalized fMRI predictive models tracking ongoing spontaneous pain in chronic pain patients, trained on 6+ mo. of densely sampled data. A true team effort. Deeply grateful to our participants! doi.org/10.1038/s41593…
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Matt Fillingim retweetledi
Yes, been saying/doing this for years .. publish when you have a complete story that is fully vetted, and preprint along the journey
I constantly get comments “this could’ve been 4-5 papers”; like no, you weren’t gonna read all that. Here is the whole picture in front of you
Oded Rechavi@OdedRechavi
The way to accelerate science is to SLOW it down. Fewer papers please! We’re drowning in meaningless text. One GREAT paper per lab per decade is more than enough. q.e.d 👇
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Matt Fillingim retweetledi
Matt Fillingim retweetledi
Benchmarking methods for mapping functional connectivity in the brain | doi.org/10.1038/s41592…
What is the best FC metric?
led by @liuzhenqi0303 in @naturemethods ⤵️
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Matt Fillingim retweetledi
Beautiful paper on #biomarkers, #neuromarkers, and psychosocial predictors of chronic pain and associated #chronicdiseases. A tour de force. @FillingimMatt @evp82
nature.com/articles/s4156…
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Matt Fillingim retweetledi
Matt Fillingim retweetledi
🔥Most important paper of 2025🔥
👉Injury/disease don't reliably predict pain
👉Biomarkers alone can't explain pain
👉PSYCHOSOCIAL factors reliably predict chronic pain
👉Painful conditions can be predicted from the SYNERGY btwn bio + psychosocial factors
tinyurl.com/jiksh
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Excited to share our new publication! See the thread and article below 👇
Matt Fillingim@FillingimMatt
Thrilled to share our new paper in @NatureHumBehav! nature.com/articles/s4156… We show that combining biological 🧬 and psychosocial 📋 data offers a much stronger, more reliable path to predicting pain and diagnosis. 🧵
English
Matt Fillingim retweetledi
Matt Fillingim retweetledi
Matt Fillingim retweetledi
Great paper demonstrating how taking into account the social context of your participants can improve your understanding and accuracy of your biomarkers. An essential read! congrats @FillingimMatt on a great paper!
Matt Fillingim@FillingimMatt
Thrilled to share our new paper in @NatureHumBehav! nature.com/articles/s4156… We show that combining biological 🧬 and psychosocial 📋 data offers a much stronger, more reliable path to predicting pain and diagnosis. 🧵
English
Matt Fillingim retweetledi
Matt Fillingim retweetledi
Our new @NatureHumBehav paper shows why we need a holistic pain biomarker framework. ML on blood tests, brain/bone imaging & genetics predicts clinical diagnoses but falls short on subjective pain. Adding psychosocial (mood, sleep, stress) boosts both. shorturl.at/vxxeO
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@NatureHumBehav Grateful to see this work featured—huge thanks to the Nature Human Behaviour team and to my co-authors. We hope this study encourages broader integration of biological and psychosocial data in pain research and clinical care.
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Matt Fillingim retweetledi
Fillingim et al. show that biological and psychosocial factors jointly predict chronic pain associated conditions
nature.com/articles/s4156…
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Huge thanks to our incredible team and collaborators.
Read the full paper here: nature.com/articles/s4156…
Grateful to @NatureHumBehav for publishing this work.
#ChronicPain #PrecisionMedicine #Biomarkers #Psychosocial #MachineLearning
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Adding psychosocial context dramatically improved prediction accuracy across all pain phenotypes.
🧬 + 📋 = 🔍
This synergy paints a richer picture of pain vulnerability and brings us closer to personalized pain care.
English
Thrilled to share our new paper in @NatureHumBehav!
nature.com/articles/s4156…
We show that combining biological 🧬 and psychosocial 📋 data offers a much stronger, more reliable path to predicting pain and diagnosis. 🧵
English