Grade centre

Grade newsletter December 2024 is out linkedin.com/posts/grade-wo…

Will have important impact on overall rating of certainty for value, utility outcome importance studies!

🚦Essentials for #evidencesynthesis #HTA #guidelines in @bmj_latest ROBVALU: a risk of bias tool for studies of people’s values, utilities or importance of health outcomes bmj.com/content/385/bm… @lmbuagbaw @hppardoh @PabloACoello @AStevens_PhD @UweSiebert9 @FengtasticXie

@grade_wg members - please check our GRADE Teams channel for communication about our upcoming meeting on May 1 & 2, 2024. Those who want to become members or want to know more direct message us please. See many of you soon.

@pahowho Ludovic Reveiz on the evidence funnel in guideline implementation @who_euro #strengtheningcapacitytodevelopguidelines

HEI's @twpiggott and @schunemann_mac played a key role in the World Health Organization's landmark decision to add three #multiplesclerosis drugs to its Essential Medicines List. Read more here: rb.gy/my5me.

Here is our launch of the @WHO_Europe manual for guideline adaptation based on @GRADE_WG adaptation methods. To be credible guidelines need to adhere to standards summarized in the book ⬇️ @ZacMunn @marge_reinap @Elie__Akl @MKlugar @gin_member

Next highlight: GRADE Adolopment guidance for approval @MKlugar @Elie__Akl @SultanShazi @schunemann_mac @GuyattGH @Reem_A_Mustafa @EBMUrology

#GRADESplit2023 Beth Radke from EPA assessing #riskofbias across studies, eg in #systematicreviews, in exposure studies ⁦@GRADE_WG⁩ - helpful to@understand the impact of confounding and other bias issues.

📢📢Join our team and make a difference! Your input can help shape guidelines for post-COVID-19 condition (long COVID). To learn more, visit: macgrade.mcmaster.ca/pccguidelines/ #LongCOVID #PostCOVIDGuidelines #Canada #CanadianHealthcare

In preparation for a lecture on #evidencebased healthcare #ebhc I came across my old markings of the original Bradford Hill 9️⃣ viewpoints on causation. What a smart and world-changing paper that still is. If you haven’t read it, see what he said about statistical significance:

Users must understand guideline recommendations-new rigorous trial shows the #RecMap enhances understanding & usability of @WHO #tuberculosis guidelines journals.plos.org/globalpubliche… who.tuberculosis.recmap.org @tamaralotfi88 @twpiggott @DocDominik @zchagla @PLOSGPH @HEI_mcmaster

GRADE stands with #Cochrane @CochraneUrology @Cochrane_US @CochraneUK @CochraneCentre @JClinEpi @schunemann_mac @mwlangendam @EBMUrology sciencedirect.com/science/articl…

The next critical piece to add to the puzzle 🧩 of getting our #guideline recs to help with self-directed health decisions. Of what value are “public health” recommendations if the PUBLIC doesn’t understand them? @RanaCharide @tamaralotfi88 @GRADE_McMaster @martinoffringa +++

Already desperately needed: Updated framework of living guidelines: acpjournals.org/doi/epdf/10.73… @AnnalsofIM @WHO @Elie__Akl @joanne_kh @hpardoh @ArnavAgarwalMD +++ following @gin_member @McMasterU checklist for #guidelines

Mark you calendars🗓: The next virtual GRADE meeting is on November 10 & 11 2022, details will follow - focus is now on the final preparations for the in-person meeting in Krakow Poland on July 12 and 13.

@gin_member conference - submit you abstracts by April 18 🗓 - we have a number of exciting sessions lining up in beautiful #Toronto - deadline for submission 🔜 g-i-n.net/conference_202… @GRADE_WG @cochranecollab @JBIEBHC @HTAiOrg @GovCanHealth @CampbellReviews

Background to the @GRADE_WG summary of findings tables for evidence about #values #outcomes #preferences #utilities @RealYuanZhang @PabloACoello @hpardoh @RMorganPhD here: sciencedirect.com/science/articl… ☟

Our theory of everything about the ecosystem of health decision-making: from fragmentation to synergy - enjoy the read in @TheLancetPH aegis of @WHO @WHO_Europe with @lorenzomoja @twpiggott @Elie__Akl @CharlieNeck @PabloACoello @ielluz @SazZuleika @RealYuanZhang @Peter_tugwell ++

This is the central figure of how #primary studies #systematicreviews #HTA #essentialmedicines #evidenceinformedpolicy #qualityassurance #coveragedecisions are connected building on @GRADE_WG #EtD but there is more to come - available here: thelancet.com/journals/lanpu…