Gengss44
3.6K posts
Scientists in China have achieved a major breakthrough in stem cell research by creating the world's first live-born chimeric monkey—a long-tailed macaque (Macaca fascicularis) exhibiting glowing green eyes and yellow fingertips under specific lighting, clear visual signs of its mixed genetic origins.
Scientists in China have achieved a major breakthrough in stem cell research by creating the world's first live-born chimeric monkey—a long-tailed macaque (Macaca fascicularis) exhibiting glowing green eyes and yellow fingertips under specific lighting, clear visual signs of its mixed genetic origins.
Unlike prior primate chimera attempts—where donor cell contribution was minimal (often <5%)—this newborn showed exceptionally high levels of chimerism. Post-birth analysis revealed donor-derived cells in 26 different tissue types, contributing between 21% and 92% (averaging ~67%) across organs, including substantial presence in the brain, heart, gonads, and placenta. This high integration rate shattered previous records and demonstrated that robust, widespread chimerism is feasible in non-human primates.
The monkey survived for 10 days before being euthanized due to respiratory failure and hypothermia, but the experiment succeeded as a proof-of-concept. It paves the way for more accurate animal models of complex human diseases (e.g., neurological disorders like Parkinson's or Alzheimer's), enabling precise gene editing in donor cells to mimic specific pathologies while studying disease progression and potential therapies in a living primate system.
The work raises ethical questions about chimeric research in primates—due to concerns over animal welfare, potential sentience implications, and the boundary between species—but advocates highlight its value as a bridge toward safer, more effective human treatments.
[Cao, J., Li, W., Li, J., et al. (2023). Live birth of chimeric monkey with high contribution from embryonic stem cells. Cell, 186(23), 4996–5010.e24.
DOI: 10.1016/j.cell.2023.10.005]
English
@puppet_sunsun Puppet sunsun MC 300k
Ca
ENhb4FtZR2o8mUnv9cY6ZuY4z1vSucHQazBataB2pump
Suomi
Gengss44 retweetledi
Gengss44 retweetledi
Gengss44 retweetledi
Gengss44 retweetledi
Gengss44 retweetledi
Gengss44 retweetledi
Gengss44 retweetledi
🔐 Just locked 48,000,000 $PYRO tokens with @Streamflow_Fi
It's on-chain. You can check the amount, time-period and recipients.
Check it out👇
app.streamflow.finance/contract/solan…
English
Gengss44 retweetledi
New MIT AI agent.
Someone just built a 12MB binary that gives AI agents full browser control.
It's called PinchTab. No Playwright. No Puppeteer. No bloated dependencies.
Plus he's kinda cute
Brady Long@thisguyknowsai
🚨BREAKING: Someone just built a 12MB binary that gives AI agents full browser control. It's called PinchTab. No Playwright. No Puppeteer. No bloated dependencies. Just a plain HTTP request and your agent clicks, types, and navigates like a human. → 13x cheaper than screenshots (uses accessibility tree instead) → Bypasses bot detection out of the box → Runs multiple Chrome instances in parallel with isolated profiles → Works with Python, TypeScript, Go, or any language that speaks HTTP → Installs in one command Most browser automation tools weigh 500MB+ and need Python environments, npm nightmares, and Docker just to say hello. PinchTab is 12MB. One binary. Zero dependencies. This is what the browser control layer for AI agents actually looks like. 100% Open Source. MIT License.
English
Gengss44 retweetledi
