Grigory Tagiltsev

This is a short video description of our recent work. Elastically loaded clathrin lattices relax to increased curvature after AFM nanodissection. @ScheuringLab @ScienceAdvances advances.sciencemag.org/content/7/33/e…

This is a molecular dynamics visualization of TGF-β receptor 1, created in @Blender using #MolecularNodes. TGF-β pathway regulates many cellular processes including cancer formation. 1+ month of dedicated work from system prep to final render. #sciart #b3d #md #cancerdrugs

Check out our new paper in @NatureComms! We report a much improved structure of the TRPV3 pentamer, analyzing its high permeability capabilities and its mechanistic ability to reversibly transition to and from the canonical tetrameric state. @ScheuringLab nature.com/articles/s4146…

Over 20 years ago, Zuker et al. discovered the mammalian sweet taste receptors Now, an exciting collaboration between our labs @ColumbiaBiochem reveals the #cryoEM structure of the human sweet receptor-key to sweet taste perception-online @CellCellPress! sciencedirect.com/science/articl…

Mature #HIV-1 contains >2000 copies of “spacer peptide 2”, but we didn’t know why. We now see that SP2 binds the matrix protein and triggers the change into its mature arrangement. Summary video from @MargotRiggi :

@Colom_D Thank you, Adai 🙂

@GrigoryTag Very nice! Congrats!!!

Was excited to determine the in situ clathrin structure for this project! That’s my first EM-structure upload to EMDB. Can I tell my mom I am a structural biologist now? 😄 #cryoET

@PlentyOf_Room Thank you:)

@GrigoryTag Those are some very pretty structures! Congratulations

Finally out!!! 🎉🎉🎉

Thrilled to announce that in January I will be opening my own lab at the Friedrich Miescher Laboratory/@MPI_Bio of the Max Planck Society @maxplanckpress in lovely Tübingen, Germany!

New preprint from my awesome labmates! It was really cool to watch from the front seat how this story unfolds! Congrats James Stacey, @F4ustus, @BriggsGroup and co-authors! 🤩

🎉 NanoLocz is Celebrating Its 1st Birthday! 🎉 To mark this milestone, we’re hosting some User Meetings for new and experienced users (all are welcome). An open session to share tips, feedback, ask questions, or simply observe to see if it can help your own #AFM analysis.

We are looking for a #PhD student to study #MolecularMachines driving #membranetrafficking by #cryoEM #cryoET #temtomo. Image processing fans are particluarly welcome.

Using #Ftractin to visualize #actin in living cells? We determined the F-tractin-F-actin structure and showed that the probe is nearly identical to #Lifeact. Check out light microscopy by Athul Sivan @RolandSoldner and #cryoEM by @DmitryShatskiy and me biorxiv.org/content/10.110…

Happy to share that our preprint on the regulation of NPC (a)symmetry is online! #teamtomo #NPC #phdlife Wouldn't have been possible without the support of the amazing @Beck_Laboratory and great collaborators outside @svenklumpe, @MandyBoermel, @WilflingFlorian!

Sharing our latest paper! Congrats to @thon_oli, @iHeart_proteins and Zhihan Wang for their amazing work! PIP2 inhibits pore opening of the cyclic nucleotide-gated channel SthK disq.us/t/4qr57vg @WCMAnesthesia, @WeillCornell, @MBiophys_WCMSKI

Congrats to @biozentrum @snsf_ch Ambizione Group Leader @FlorentWaltz on this stunning study🤩 of respirasome structure & organization inside native cells! It's amazing how quickly in situ #cryoET is advancing. Read Florent's thread🧵 for the high-resolution details🔎🦠 #TeamTomo

😍😍😍

@AlisaIakupova my US visa had been in admin processing for 1.5 years already 😂, the first 5 processings took one month each

my 4th admin processing for a US visa, how many months will you give this time? last time it was 8 🤕

PostDoc Position Now Open! 🎞 Join our High-Speed AFM team in Leeds Application Deadline: 1st September 2024 Apply Online Here: jobs.leeds.ac.uk/EPSPA1117

Wow!! Congrats!!!