Jonathan D. Grinstein

629 posts

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Jonathan D. Grinstein

Jonathan D. Grinstein

@GrinsteinJ

Scientist turned storyteller. North American Editor @inside_pm. for story leads: [email protected]

San Diego, CA Katılım Mayıs 2016
161 Takip Edilen584 Takipçiler
Legacy (Fan)
Legacy (Fan)@LegacySiu·
Can you guess the player? Very Hard
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Legacy (Fan)
Legacy (Fan)@LegacySiu·
World cup 2010 Edition Guess the player who won the golden Boot 99% of fans will fail Very Difficult 🥷
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Rodger Sherman
Rodger Sherman@rodger·
Shrey spelling 32 words in 90 seconds to win the Spelling Bee is the new greatest athletic accomplishment of 2026. I don’t even know how he said the letters that fast. Got a “Holy Mackerel” out of @minakimes
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Kevin Davies
Kevin Davies@KevinADavies·
Time flies... last month was the 10th anniversary of the first base editing report, published in @Nature, led by Alexis Komor in the lab of @davidrliu. A worthy excuse then to re-post this fun 60-minute interview with Alexis and @NicoleGaudelli on the origins of base editing.
Kevin Davies@KevinADavies

Thrilled to release the latest episode of #Guidepost--starring Alexis Komor & Nicole Gaudelli--on the remarkable origins of Base Editing. Unquestionably the best episode so far! @CRISPRjournal @BeamTx @synthego Spotify: open.spotify.com/episode/5wihQJ… Soundcloud: soundcloud.com/guidepost/ep-1…

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Simon Barnett
Simon Barnett@SimonDBarnett·
Respectfully disagree with this in totality. Aging is a systemic, global assault on the body. It's caused by internal deterioration and accelerated by accumulated environmental insults. Aging is the body's progressive failure to maintain its low-entropy state, a losing war against disorder. Evolution did not select for us to have indefinite maintenance machinery. We do not have (nor are we close) to a full answer to this phenomenon. The closest things we do have resemble public health programs and disease prevention measures (i.e. screening). And to be clear, I am a big believer in targeted longevity medicines, of which obesity drugs are an exemplar. But genomic medicine specifically may be one of the least well-fit remedies for aging. We cannot edit our way out of multi-tissue deterioration. Just eat your veggies.
MTS@MTSlive

We asked @maxmarchione: what happens after we solve obesity? "We still have all of the things that cause aging."  "We haven't really been able to slow aging. Aging is very systemic." "Even if you take the Bryan Johnson approach to aging, you maybe only add an extra 10 years to life, which is not an awful amount." "I think the kind of 10-year plus primary therapeutic modality is likely going to be genomic medicine." "If you can modify the genome, you can actually modify how DNA encodes for RNA, which produces proteins and peptides. So you can actually change the proteins and peptides your body produces by modifying DNA."

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Pearl Freier
Pearl Freier@PearlF·
I remember reading about an HHS employee in 2020, Caputo, who was trying to suppress CDC reports & data. That was similar to some of the stuff that seems to be happening all the time now. At one point he was on camera claiming he saw shadows & that he knew "they were after him." He went on medical leave after that politico.com/news/2020/09/1…
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Jonathan D. Grinstein
Jonathan D. Grinstein@GrinsteinJ·
@PearlF @Inside_PM Great insight! I imagine what I addressed is just the tip of the iceberg and that there's a vast history to be examine to pin down what has driven decision-making of these institutions...instead of just assumptions based on administration (of which I'm guilty).
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Pearl Freier
Pearl Freier@PearlF·
The FDA under Hahn had its problems but it seemed like Hahn was more ethical than Makary & he seemed to take advice from Eric Topol on not rushing through an EUA on the vaccines months earlier even though the WH pushed for that. And Azar was HHS Secretary & not RFK jr. The CDC seemed to be in worse shape at the time than the FDA was that year
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NEDU𓀀
NEDU𓀀@NEDUszn8·
Without mentioning DAVID BECKHAM and EDINSON CAVANI Guess a player that has played for both Manchester United and PSG LEVEL: VERY DIFFICULT 🤯
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Legacy (Fan)
Legacy (Fan)@LegacySiu·
Guess the player? 👀 Very Hard
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MȺɆŁ🗽
MȺɆŁ🗽@UTDMael·
Guess the player💨💨 Absolutely nobody can get this❗️ Level=pro
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Legacy (Fan)
Legacy (Fan)@LegacySiu·
Name an Italian that has played for Manchester United You can’t
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Legacy (Fan)
Legacy (Fan)@LegacySiu·
Guess the player VERY HARD
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Legacy (Fan)
Legacy (Fan)@LegacySiu·
Guess the national team VERY HARD
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Legacy (Fan)
Legacy (Fan)@LegacySiu·
Guess the player Very Hard
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