Guillaume Ramstein

Are you a wet lab biologist ready to shape the future of AI in genomics? CSHL is hiring a PhD-level Research Associate to join a collaborative team of genomic scientists and AI researchers. Help build the next generation of AI models for genomics! plz RT jobrxiv.org/job/cold-sprin…

🌟 Excited to announce AMPLIFY, our latest protein language model that challenges the scaling trend! While current models like ESM2 15B rely on billions of parameters, AMPLIFY achieves superior performance with only 350M parameters. 1/7

Excited that CREME (Cis-Regulatory Element Model Explanations) is published in @NatureGenet! Work led by @ToneyanSh! tl;dr CREME interprets rules of gene regulation learned by genomic deep learning models using carefully designed in silico perturbations. rdcu.be/dT3kq

PlantCaduceus - Cross-species modeling of plant genomes Led by Jingjing Zhai and Aaron Gokaslan, with the Kuleshov lab, we’re having our “ChatGPT moment” with DNA Large Models. PlantCaduceus predicts functional DNA sequences with single base resolution across flowering plants.

📢 We have an available #PhDposition in #AgriculturalEcology and #MachineLearning: An Underground #VideoTracking System to Characterise Novel #EarthwormPlant Interactions🌱🪱 Deadline 31 August 2024 Read more and apply here: phd.tech.au.dk/for-applicants… @qgeissmann

📣 Come join us for a 3-day intensive course in Data Analytics and Digital Tools Applied to Livestock Production 6-8 November 📣 Instructor: @gjmrosa. 📣 Read more and sign up here: bit.ly/4etV297 #DataAnalytics #DigitalTools #Livestock @GebreGrum @GoutamSahana

fastDFE: Fast and Flexible Inference of the Distribution of Fitness Effects buff.ly/3VGBRlk #science #evolution #biology #genome

Join us for our next Kipoi Seminar with Thomas Pierrot @thomas_pierrot @instadeepai! 👉The Nucleotide Transformer initiative: building and evaluating robust foundation models for genomics 📆Wed May 8, 5:30pm CET 🧬tum-conf.zoom.us/meeting/regist…

Two new chapters from my open-access textbook in human population genetics are now online: - Population structure: I. Ancestry estimation - Population structure: II. More about admixture web.stanford.edu/group/pritchar…

We have received lots of interest in AlphaMissense, the @GoogleDeepmind model predicting the probability of a missense variant being pathogenic, since its release in September. Today we are updating the license terms for AlphaMissense predictions to also allow for commercial use.

If you have a Ph.D. in population genetics, computational biology, or bioinformatics and an interest in human health, you should come to Denmark for your postdoc and help us understand the role sex chromosomes play in autism. international.au.dk/about/profile/…

🌱🚨 Exciting news! We're launching a company to develop next-gen crop breeding tools, speeding up seed-to-seed generation time. Seeking experts in plant biotechnology, AI/ML, and agricultural biotech commercialization. Links in comments 🚨 🌱

PLEASE RT 🌞 QGG's #SummerUniversity courses are online, and you can find an overview here: qgg.au.dk/en/education/s… Deadline for application is 15 March 2024 🌞 @dougthespeed @GoutamSahana @GuillRamstein @lljanss

I've written up a "crash course" on population genetics parameters useful for thinking about recent selection, heritability, and group differences (as part of a longer write-up on these concepts). #h.8wg4yyfhqbt6" target="_blank" rel="nofollow noopener">gusevlab.org/projects/hsq/#… I'll summarize the key points here 🧵:

Check out and read about our new #partnership with @Wikifarmer_com recrop-cost.com/NewsAndActivit… @HotPlant1 @costprog

Congratulations to all the collaborators, and thanks very much for all your efforts and supports! Looking forward to more fantastic outcomes from the FarmGTEx in the coming year.⁦@QGG_AU⁩ ⁦@NatureGenet⁩ nature.com/articles/s4158…

New from Lippman Lab and recent PhD grad Dani Ciren on bioRxiv: “A striking paradox is that genes with conserved protein sequence, function and expression pattern over deep time often exhibit extremely divergent cis-regulatory sequences.” More inside… biorxiv.org/content/10.110…

#savethedate for our first annual meeting in beautiful Murcia, Spain @costprogramme #recrop22157 #recrop #meeting #phd #phdchat #phdtalk

Save the date 📆: The 2025 @GordonConf on Quantitative Genetics and Genomics is scheduled for Feb 16-21, 2025 in Lucca, Italy (pics from 2019!) 🤩 Josephine Pemberton and I co-chairing, tentative theme: Quantgen in time and space 🕛🌿 Associated GRS: Feb 15-16 ✨ More soon!

A few thoughts on the recent set of papers torture testing genomic deep learning for predicting individual-level gene expression [ pubmed.ncbi.nlm.nih.gov/38036790/ , pubmed.ncbi.nlm.nih.gov/38036778/ , pubmed.ncbi.nlm.nih.gov/38036789/ ]. First a brief summary 🧵: twitter.com/SashaGusevPost…