Hailey Edelstein

Delighted to share the final version of this paper out now! I led this project with @amparo_cosio during my PhD in @TheLeonardLab to investigate how we could program smart cell therapies to sense and respond to markers of disease—taking inspiration from natural human receptors!

A new study by @LurieCancer member Joshua Leonard, PhD, could ultimately enable the development of safer and more effective treatments for #cancer using ‘smart’ cell therapies." spr.ly/6019f2Yfv @TheLeonardLab @NUSynBio @NorthwesternEng @HaileyEdelstein @amparo_cosio

@BashorLab @TheLeonardLab @amparo_cosio @nchembio Thank you!!

@TheLeonardLab @HaileyEdelstein @amparo_cosio @nchembio Congrats on the fantastic work, Josh, Hailey, and others. An elegant design strategy that meaningfully advances mammalian sense and respond capabilities!

How can we combine the exquisite function of natural receptors with the programmability of synthetic biology? Check out this exciting new story led by @HaileyEdelstein and @amparo_cosio out today in @nchembio

Thank you to @NorthwesternEng for covering our paper! mccormick.northwestern.edu/news/articles/…

@BlaiseKimmel @amparo_cosio @TheLeonardLab Thank you Blaise!!

Delighted to share the final version of this paper out now! I led this project with @amparo_cosio during my PhD in @TheLeonardLab to investigate how we could program smart cell therapies to sense and respond to markers of disease—taking inspiration from natural human receptors!

Excited to share our work @NatureComms on biomembranes, lipid rafts, drug delivery, and extracellular vesicles (EVs). We used lipid-protein interactions to control protein trafficking and improve functional delivery of transcription factors > 50X! tinyurl.com/ycprfywe (1/8)

I’m thrilled to finally share this work from the Leonard lab and grateful for a fantastic team, especially my coauthor @amparo_cosio!

Red blood cells have some wildly cool capabilities – what if we could engineer them to work as living diagnostics? Check out this exciting first step (led by @TaylorDolberg & @taylor_gunnels): biorxiv.org/content/10.110…

VERY excited to welcome this paper out in @natBME where we introduce the GEMINI platform for engineering multifunctional extracellular vesicles as versatile, programmable, biological delivery vehicles nature.com/articles/s4155…

What a fun collaboration with @NehaPKamat & @UWproteindesign led by @jperuzz & @taylor_gunnels - dig in for some fascinating EV science and useful EV bioengineering tools that we are thrilled to share

Have you ever wondered how to improve loading of protein cargo into extracellular vesicles? Excited to share our latest work exploring how lipid-protein interactions may be leveraged to direct proteins into extracellular vesicles! tinyurl.com/45sdm55m 🧵 1/6

Hello darkness my old friend...Have you ever had your transgene or synthetic gene circuit silence? Check out this awesome collaborative review by many leaders in mammalian synbio. sciencedirect.com/science/articl…

We’re thrilled to be selected by @abbvie for their 2022 AIM award! Great work team! @TheLeonardLab @jdrosanelli @DevinStranford @HaileyEdelstein

I’m thrilled to introduce a story that has been many years in the making – the GEMINI platform for engineering multifunctional extracellular vesicles as versatile, programmable, biological delivery vehicles biorxiv.org/content/10.110…

Check out a fun new perspective on super-cool recent work by @ElowitzLab, Richard Murray and team in @GENBiotechJrnl (with @HaileyEdelstein and @_gauribora ) liebertpub.com/doi/10.1089/ge…

Happy to share that our study on engineering nanoscale decoys to fight COVID-19 is now published! A big thank you to the team for your hard work, advice, & mentorship! (@TheLeonardLab @NehaPKamat @DevinStranford @roxi_mitrut )

Very psyched to see this paper out in the world - it is the review we wish existed! Hope this is as much fun to read as it was to write with @LeonardoMorsut, @HaileyEdelstein, and @JanvieManhas with great input from Terry Sheppard from @nchembio

I’m so proud to see this review finally out! The synthetic receptor space is evolving quickly and capturing that development here was all around fun! Thanks to my co-authors for all of the brainstorms and teamwork. It’s been a blast! @JanvieManhas @TheLeonardLab @LeonardoMorsut

Happy to share our new review on the power of using process control concepts to understand and build genetic programs in mammalian cells by @dray_kate @HaileyEdelstein @kdreyer96 @NorthwesternEng @NUSynBio sciencedirect.com/science/articl…

@PatrickSDonahue @tera_levin Can’t forget the obligatory hand lotion for the cold Chicago winters! I think our lab has more than a dozen varieties across all our desks at this point 🥶

@tera_levin Omeprazole, triple antibiotic ointment, excedrin, military energy gum, definitely an extra pair of clothes or two, rebuild, whiskey. Did I miss anything @HaileyEdelstein ?

Pretty happy with how our lab emergency personal supplies drawer is coming together! Any other ideas for what would be useful? Suggestions welcome!