van Oosten-Hawle lab
738 posts
van Oosten-Hawle lab
@HawleLab
Twitter feed of the van Oosten-Hawle lab Assistant Professor @unccharlotte
Charlotte, NC Katılım Eylül 2017
549 Takip Edilen682 Takipçiler
We are so happy to announce we have received the NOA for an R01 project studying molecular mechanisms of degeneration and cognitive decline involving HSF1 in Huntington's disease. We are recruiting!!!
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Congratulations to Katie for winning the best oral presentation prize for her research talk! 🏆👏 #moreproudPImoments 😊Excellent representation from @UNCCBiology
van Oosten-Hawle lab@HawleLab
Valeria @ValeriaUva1 and Katie @katiegkessler from the lab are excited to showcase our latest research today at the Graduate Research Symposium @unccharlotte 🧬🔬 #proudPI
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Valeria @ValeriaUva1 and Katie @katiegkessler from the lab are excited to showcase our latest research today at the Graduate Research Symposium @unccharlotte 🧬🔬 #proudPI
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Had a fabulous time celebrating our new R1 status and the students and faculty researchers who made it possible! 💚🤙🎊 @unccharlotte
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Grad-student Tatiana Moreno in the lab wrote a comprehensive review about autophagy in human aging models! Go check it out!
Congratulations, Tatiana
Cyndi Chua@ChuaCyndi2020
🧬🔍 Monitoring Autophagy in Human Aging: Key Cell Models and Insights! @cellrepairlab & @kumsta explore key cell models and insights into monitoring autophagy in human aging. 📖 Read more: imrpress.com/journal/FBL/30… #Autophagy #AgingResearch #CellBiology #Longevity
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The 2025 Gordon Research Conference and Gordon Research Seminar on Stress Proteins in Growth, Development and Disease
will be held July 5 -11 at Sunday River in Maine. Submit your poster and short talk abstracts for both conferences by June 8! grc.org/stress-protein…
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Congrats to our team and collaborators for getting this story together and published in @CRC_AACR!
Cancer Research Communications@CRC_AACR
Recently published: MYC and #HSF1 Cooperate to Drive Sensitivity to #PLK1 Inhibitor Volasertib in High Grade Serous #OvarianCancer, by Imade Williams et al. doi.org/10.1158/2767-9… @carpenter_lab @JoeRDelaney1 @kennyneph @IUMedSchool @IUCancerCenter #HGSOC #openaccess
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Thrilled to announce Dr. Mehdi Mollapour @MedMol as our new CSSI President (2025–2026) and Dr. Adrienne Edkins @Bio_BRU as President-Elect (2027–2028)! Huge thanks to Dr. Lea Sistonen @sistonheat for her dedicated service as Immediate Past President. bit.ly/4gCGEfB
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From all of us at Cell Stress Society International, warm wishes for a healthy and peaceful holiday season! May we find renewal and resilience, just like the cells we study, as we head into the new year. Here’s to continued growth, discoveries, and brighter days ahead!
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Cheers to another great year in the @MedMol @bourboulialab @TheMarq1 lab group @UrologyUpstate! Happy holidays all! ❄️ ❄️
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Snapshot from this year’s holiday lunch! Feeling so grateful for my incredible team and everything we’ve achieved so far. Wishing everyone a wonderful holiday season! 🎉✨
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📢 Dr Bourboulia
Secreted Hsp90 (eHsp90) has ATPase activity but does it engage with ATP in the extracellular environment?
eHsp90 and MMPs in tumor invasion involves balance of TIMP2/AHA1 binding, impacting ECM
PTMs impact eHSP90 secretion
Src impacts Hsp90AA/AB phosphorylation
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Have you checked out our latest @NatureComms article? Learn about how #phosphorylation can impact the conformation of the ubiquitous protein #HSP90 thus opening therapeutic avenues & drugging the undruggable #epichaperome #CancerResearch #PrecisionMedicine nature.com/articles/s4146…
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As a new faculty member at UNC Charlotte, I am excited to present my first seminar here. @ShanYanLab Thanks for the picture!
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Thanks @buchnerlab_tum for organizing such an amazing meeting! Sorry for missing it. So many familiar faces @Bio_BRU @lab_colombo C. Prodromou @bourboulialab @HawleLab @TheMarq1 B. Blagg @BiophysK @KravatsLab @AgardLab M. Mayer.
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Excited to see our work highlighted by @NatureComms! Discover how #HSP90 #phosphorylation fuels #epichaperome formation, revealing new insights into #cancer aggressiveness and #pluripotency. Collaboration with @UofNH @unipv @MSK_DeptOfMed
Nature Communications@NatureComms
Researchers from @chiosislabmskcc; @MSKCancerCenter and their collaborators show how HSP90 phosphorylation drives epichaperome formation, linking this process to cancer and pluripotency. nature.com/articles/s4146…
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Thanks to my group @SarahJean258 @JenniferHeritz @BeckySagerMDPhD & collaborators @TheMarq1 @bourboulialab - FC-FRET helped us quantitatively visualize Protein Phosphatase-5 conformation changes in cells @Hsp90Machine- sciencedirect.com/science/articl…
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Nobel Laureate and HMS Professor Gary Ruvkun shared lighthearted tales about his start, a science revolution, and the power of worms.
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Did you ever wonder about olfaction and anosmia in animals.
Why do worms love some odors and avoid some.
Here is us chasing C elegans in the wild and their microbiome. Dig in if you have time ( you may find Leucine and an olfactory GPCR within).
elifesciences.org/reviewed-prepr…
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