Xiaojun Ren Group at UNC Charlotte

ErbB family receptor dimerization dynamics and dysregulation via long-term single-molecule imaging: Cell cell.com/cell/fulltext/…

“Spatial Organization of Epigenetic Information by Phase Separation” presented by Xiaojun (XJ) Ren, Ph.D. on Tuesday, April 21, 2026 – 11:00 am – 12:00 pm 1131 Bioinformatics Host: Jill Dowen Join us for our last seminar of the Spring semester.

It is so nice to see our Molecular Cell paper is out today! Thanks for my students and collaborators. Without you, this is impossible. Thanks for all reviewers! Your constructive comments make the paper much better!!!

New article about our research: science.charlotte.edu/2026/02/23/unc…

@TrumanLab @NatureComms @UNCCBiology @unccharlotte Congrats! Nice work!

Super excited to share our latest work on the Hsp70 chaperone code "Mechanosensor-mediated Hsp70 phosphorylation orchestrates the landscape of the heat shock response" out now in @NatureComms :nature.com/articles/s4146…. @UNCCBiology @unccharlotte #hsp70

Transcriptome-wide mRNP condensation precedes stress granule formation and excludes new mRNAs dlvr.it/TPffCB

Multiscale structure of chromatin condensates explains phase separation and material properties | Science science.org/doi/10.1126/sc…

Happy to see this coming out at JCB!

@dan_gard @ChancellorGaber @unccharlotte @UNCCBiology @TrumanLab Congrats

I'm absolutely thrilled to share that I've received a Notice of Award for my $3.7 million R01 grant!

@cxiong30 Thanks!

@XR_Lab This is amazing Dr. Ren! So glad to see this amazing instrument. Wishing all the best to you and your lab!

Excited to have this powerful single-molecule microscopy installed. Exciting discoveries will come soon……

@TrumanLab @UNCCBiology @unccharlotte Congrats

Grateful to have been awarded the first UNC Charlotte Klein College of Science award for Research and Scholarship (KNOBEL) 🔥🔥🔥 @UNCCBiology @unccharlotte

We are pleased to announce the Inaugural 2025 Carolina Symposium on Genome Integrity and Chromatin Regulation on June 11, 2025 @unccharlotte Free registration, abstract for talk/poster: biology.charlotte.edu/announcing-the…

Cryo-EM reveals mechanisms of natural RNA multivalency | Science science.org/doi/10.1126/sc…

Imaging single endogenous RNA in live cells comes true!

Really excited to unveil sandbox.bio, an interactive playground for learning bioinformatics command-line tools like bedtools, bowtie2, and samtools (and more to come!) 🧑‍💻 🧬 Thanks to @aaronquinlan, @BenLangmead, and @mike_schatz for feedback and tutorial ideas.

My lab is looking for a postdoctoral fellow. Exciting opportunities for LLPS, single-molecule imaging, genomic approaches, and genetic engineering. Pls RT

@bsabari @NatRevMCB @Heankel_ Congrats! It was a nice read.

I am excited to share our review, published online today @NatRevMCB. Pilong Li, Gaofeng Pei, @Heankel_, and I review the current literature on the regulation of transcription by condensates, large length-scale assemblies of complexes (Figure 1). nature.com/articles/s4158…

Threonine-rich carboxyl-terminal extension drives aggregation of stalled polypeptides: Molecular Cell cell.com/molecular-cell…

@evajge @ShanYanLab Will do! What’s your office number? I would love to visit your lab and have chat with you.

@XR_Lab @ShanYanLab It’s been many years since I’ve worked on PRC2, but if you’re ever around the chemistry department, stop by and say hi!

As a new faculty member at UNC Charlotte, I am excited to present my first seminar here. ⁦@ShanYanLab⁩ Thanks for the picture!