Mark Histed

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Mark Histed

Mark Histed

@HistedLab

Neuroscientist. We aim to understd brain networks and brain wiring, using lasers & neuro AI. Prev: policy for @democracypolicy. Personal views. Not a lab acct.

Washington, DC Katılım Mayıs 2013
826 Takip Edilen2.7K Takipçiler
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Mark Histed
Mark Histed@HistedLab·
New preprint, on 'sequence filtering'. Led by @CianaDeveau, Z Zhou. We see this as a key step forw on how cortex works. All cortical areas have dense exc-exc recurrent connectivity. What do these connections do, esp in sensory ctx? Our data say: they do dynamics/time. 1/4
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Mark Histed
Mark Histed@HistedLab·
and if any one is wrong we can accept it. In contrast, some big clinical trials maximize rigor at high cost. A great science ecosystem has a mix of different approaches. #metascience
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Mark Histed
Mark Histed@HistedLab·
High-risk, high rigor, and low cost in science are tradeoffs: for any line of research we generally get to choose just two. For some emerging fields, we want to throw a lot of high-risk and low-cost darts …
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Mark Histed
Mark Histed@HistedLab·
So we choose a reasonable rigor std, do our best to peer review, & accept some errors, worked out by followup work. (There are many issues w/ glam journals, over-selling, favoring huge labs—etc. But this 'some are wrong' issue is just the nature of reality.) /end
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Mark Histed
Mark Histed@HistedLab·
This framework is well-worked out in theory—we must choose an error criterion ("wrong"), which comes w/ a cost in time/$. This isn't ex it (need a cost term), bt same idea, fm David Heeger's notes. Type 1/2 errors, sensitivity/specificity: same idea. cns.nyu.edu/~david/handout…
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Mark Histed
Mark Histed@HistedLab·
A good number of papers in Science and Nature are wrong... and that's not a bad thing. (What's something everyone in your field knows but people outside the field don't?) 1/
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Mark Histed
Mark Histed@HistedLab·
Going to start calling myself a Lincoln liberal.
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Mark Histed
Mark Histed@HistedLab·
On efficient orgs: “The antidote to a corrupted metric is usually direct contact w/ reality— interviews, frontline observations, case reviews, unscripted convos. Leaders who do this well build it into their routines structurally…” @pahlkadot Yes. Accords with my experience.
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Sheena Josselyn
Sheena Josselyn@sjo09·
Excited to share our latest in @CurrentBiology (they who publish the coolest papers!) Memories are encoded by sparse neuronal ensembles (engrams). But most evidence comes from "simple" associative learning tasks. What about more integrative memories like spatial navigation?
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Mark Histed
Mark Histed@HistedLab·
And everything that comes out needs heavy and careful checking from me with my human brain.
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Mark Histed
Mark Histed@HistedLab·
💯 The real high risk science is “Let 1,000 flowers bloom“ science, which spreads money around to many many different individuals to pursue their best ideas.
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Mark Histed
Mark Histed@HistedLab·
@samhaselby In. A coalition of scientists and historians should be formed to do this
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Mark Histed
Mark Histed@HistedLab·
I don’t thing discliplines should fight with each other, we all have different things to contribute and should pick each other up, and many advances come from people in different fields working together. That said this interpretation 👀
Dr Kareem Carr@kareem_carr

The findings suggest that Psychology research, despite it's bad reputation, is overall more robust than Economics, which is often put forward as the gold standard of social science research.

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