Huan Edmonds

185 posts

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Huan Edmonds

Huan Edmonds

@HuanEdmonds

Postdoc in the Zhang lab at @broadinstitute and @MIT. Previously @ElowitzLab at @Caltech. Used to go by Grace Chow. 🧬 I luv SynBio!

Cambridge, MA Katılım Mayıs 2015
398 Takip Edilen474 Takipçiler
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Huan Edmonds
Huan Edmonds@HuanEdmonds·
Can we use RNA to insert kilobases of DNA into the human genome, opening up a new way to engineer cells or treat disease? Excited to share our latest work turning a retrotransposon (a “jumping gene” with an RNA intermediate) from songbirds into a genome editing tool. 🧵 (1/7)
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Michael Baym
Michael Baym@baym·
Hot off the press! Our latest paper led by @fernpizza , understanding how plasmids evolve inside individual cells. These small pieces of self-replicating DNA live inside bacteria and can transfer antibiotic resistance genes, but they also compete with one another to replicate. 1/
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Max Wilkinson
Max Wilkinson@maxewilkinson·
The Wilkinson Lab is open for science! @MSKCancerCenter 🧬We'll be finding funky new RNA biology, mainly by looking at reverse transcriptases (i.e. the Best Enzymes In The World)🧬
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Katie Galloway
Katie Galloway@GallowayLabMIT·
🚨New paper alert!🚨 Cells integrate signals into decision-making. But how do levels of signaling influence cell-fate transitions? Is more always better? Or is there an “optimal” level for cell-fate programming? If we could tune signaling, could optimize production of neurons? Read on! (1/n)🧵
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Akanksha Thawani, PhD
Akanksha Thawani, PhD@AkankshaThawani·
🚨 Extremely excited to share that I’m joining @Columbia University as an Assistant Professor! The Thawani Lab will explore how the mobile genome works—how transposons shape us, our DNA and how they can be harnessed to build useful technologies. We’re hiring at all levels! If you're interested in transposons, genome biology, cryoEM, RNA, chromatin, or tool building—let’s talk! Particularly interested in enthusiastic technicians and postdoctoral fellows @ColumbiaBiochem #NewPI #RNANEWS
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Huan Edmonds
Huan Edmonds@HuanEdmonds·
@WangXiaoLab Thank you so much Xiao! And for the fun and helpful discussions along the way!
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Huan Edmonds
Huan Edmonds@HuanEdmonds·
Can we use RNA to insert kilobases of DNA into the human genome, opening up a new way to engineer cells or treat disease? Excited to share our latest work turning a retrotransposon (a “jumping gene” with an RNA intermediate) from songbirds into a genome editing tool. 🧵 (1/7)
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Huan Edmonds
Huan Edmonds@HuanEdmonds·
Full story here! doi.org/10.1038/s41467… We hope this expands the toolkit of retrotransposon-based gene editors. Also, don’t miss related work from others like @CollinsRNPLab, who have also illuminated how R2 can be used for mammalian genome engineering. (7/7)
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Huan Edmonds
Huan Edmonds@HuanEdmonds·
This project was a huge team effort. Shoutouts to: @maxewilkinson: structure + biochemistry + birb animation 🐦‍⬛🥚 @HongyuChenChem and @LDangliang: RNA chemistry @zhangf: incredible mentorship … and all the amazing authors that worked tirelessly to make this possible. (6/7)
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Kalli Kappel
Kalli Kappel@KalliKappel·
In the nucleus, many intrinsically disordered proteins (IDPs) form condensates. What IDP sequence features drive this behavior? We developed CondenSeq, a high-throughput method to measure nuclear condensate formation & applied it to ~14000 IDPs to find out rdcu.be/eq975
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Xin Jin, PhD
Xin Jin, PhD@xinjin·
Honored to be an HHMI FHS! Grateful to colleagues who push me to think deeply, and students whose curiosity & energy make the lab a joy. My grad advisor said in genetic screens, you don’t get what you want—you get what you deserve. Hope we are deserving! hhmi.org/programs/freem…
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Cell
Cell@CellCellPress·
In the latest issue! Reprogrammable RNA-targeting CRISPR systems evolved from RNA toxin-antitoxins dlvr.it/TK21Y8
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Huan Edmonds
Huan Edmonds@HuanEdmonds·
The amount of bizarre political advertisements on my feed is getting out of hand 😳 is it finally time to swap platforms? I am kedmonds.bsky.social, I’ll try to re-add people there too (this feels like getting a new phone in the 2000s).
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Kalli Kappel
Kalli Kappel@KalliKappel·
The Kappel Lab is opening soon at UCLA and we’re hiring Staff Scientists to help lead our wet-lab projects & to assist with lab management! We have open positions for candidates with a PhD & for recent college grads. Learn more and apply: forms.gle/76inzTL6FoTcRP… Please RT!
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Keşfet

@fernpizza @MSKCancerCenter @AkankshaThawani @Columbia @ColumbiaBiochem @Akash_Guru_ @gracekc @KalliKappel