Alex Hurben

@RBoggess14 Glad you enjoyed our paper!

Very cool! Methylglyoxal (MG) is a toxic byproduct of glycolysis and a current hot topic of research. Addition of MG to a cell has issues with MG transport through the cell membrane. This paper shows a novel photocaged MG that can enter cells. #CSUICM2022 pubs.rsc.org/en/content/art…

@WakeDukeChem Thank you Leigh, these words are honestly too kind!

Glad there is room for papers like this to be published. pubs.acs.org/doi/10.1021/ac… I hope there will be some follow up on the original ACS Med. Chem. Lett. paper on the supposed probe. Some other references on metal impurities linked below, if useful.

@fabermdphd @Noman_abdullah @TLan_OChemLover Absolutely!

This would have been perfect for our pandemic #medchem journal club @Noman_abdullah @HurbenAlex @TLan_OChemLover Lysine-Targeting Reversible Covalent Inhibitors with Long Residence Time pubs.acs.org/doi/10.1021/ja…

@StephanHacker2 @trety001 @tretyakova_lab @ChemCommun Thanks Stephan!

Interesting paper by the group of @trety001 @tretyakova_lab with first author @HurbenAlex in @ChemCommun. They developed photocaged methyl glyoxal probes to study protein glycation with spatiotemporal control in cells.

@fabermdphd @tretyakova_lab @UMN_MedChem Thanks!!

@HurbenAlex @tretyakova_lab @UMN_MedChem Congrats! So happy this is finally out

Excited to share our new chembio tool! Photocaged dicarbonyl probe provides spatiotemporal control over protein glycation - now published in Chemical Communications pubs.rsc.org/en/content/art… @tretyakova_lab @UMN_MedChem

BenchMarks In this issue of Cell: The Rise of Molecular Glues,The Rise of Molecular Glues zpr.io/HVB92

We are proud to welcome @DuerfeldtLabs to @UMN_MedChem. Read more about this new faculty member and the important research contributions of his group. pharmacy.umn.edu/news-and-event…

Excellent review by @chembiokevin @SWM_Crossley @christhechang on Activity-Based Sensing! Lots of great inspiration for studying the dynamics of cellular metabolites though chemoselective imaging agents and expanding beyond to activity based therapeutics! doi.org/10.1002/anie.2…

It is #CBITG Symposium today. I look forward to kicking things off with a webinar on how to build a long-lasting and satisfying career in science. Wish I was at @UMNChemistry, but sending everyone virtual greetings!!! ow.ly/v0jF30qDlAG

Excited to speak at the Minnesota CBITG symposium tomorrow, Wed, May 20. cbitg.chem.umn.edu/symposium-2020… You can still register for the Webinar: umn.zoom.us/webinar/regist…

I am looking forward to participating in 2020 #CBITG Symposium, organized by fantastic #ChemicalBiology graduate students at @UMNChemistry. Wish we were able to do this in person, but virtual is the new real! ow.ly/aI9F30qDlye